• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Polypeptide N-Acetylgalactosaminyltransferase 1 (GALNT1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1382564

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc… More details

$1840 / 0.5 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1), Recombinant Protein
Full Product Name
Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1), partial
Product Gene Name
GALNT1 recombinant protein
Product Synonym Gene Name
GALNT1
Sequence
MRKFAYCKVV LATSLIWVLL DMFLLLYFSE CNKCDEKKER GLPAGDVLEP VQKPHEGPGE MGKPVVIPKE DQEKMKEMFK INQFNLMASE MIALNRSLPD VRLEGCKTKV YPDNLPTTSV VIVFHNEAWS TLLRTVHSVI NRSPRHMIEE IVLVDDASER DFLKRPLESY VKKLKVPVHV IRMEQRSGLI RARLKGAAVS KGQVITFLDA HCECTVGWLE PLLARIKHDR RTVVCPIIDV ISDDTFEYMA GSDMTYGGFN WKLNFRWYPV PQREMDRRKG DRTLPVRTPT MAGGLFSIDR DYFQEIGTYD AGMDIWGGEN LEISFRIWQC GGTLEIVTCS HVGHVFRKAT PYTFPGGTGQ IINKNNRRLA EVWMDEFKNF FYIISPGVTK VDYGDISSRV GLRHKLQCKP FSWYLENIYP DSQIPRHYFS LGEIRNVETN QCLDNMARKE NEKVGIFNCH GMGGNQVFSY TANKEIRTDD LCLDVSKLNG PVTMLKCHHL KGNQLWEYDP VKLTLQHVNS NQCLDKATEE DSQVPSIRDC NGSRSQQWLL RNVTLPEIF
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
12,046 Da
Sequence Positions
1-559
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
602273
3D Structure
ModBase 3D Structure for Q10472
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GALNT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GALNT1 purchase

MBS1382564 is a recombinant protein targeting GALNT1. Also known as Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for GALNT1. It may not necessarily be applicable to this product.

NCBI GI #
13124891
NCBI GeneID
2589
NCBI Accession #
NP_065207.2
UniProt Primary Accession #
Q10472
UniProt Secondary Accession #
Q86TJ7; Q9UM86
UniProt Related Accession #
Q10472
GenBank Nucleotide #
NM_020474.3
NCBI Official Full Name
polypeptide N-acetylgalactosaminyltransferase 1
NCBI Official Synonym Full Names
polypeptide N-acetylgalactosaminyltransferase 1
NCBI Official Symbol
GALNT1
NCBI Official Synonym Symbols
GALNAC-T1
UniProt Protein Name
Polypeptide N-acetylgalactosaminyltransferase 1
UniProt Synonym Protein Names
Polypeptide GalNAc transferase 1; GalNAc-T1; pp-GaNTase 1
Protein Family
Polypeptide N-acetylgalactosaminyltransferase
UniProt Gene Name
GALNT1
UniProt Synonym Gene Names
GalNAc-T1; pp-GaNTase 1
NCBI Protein Information
polypeptide N-acetylgalactosaminyltransferase 1

NCBI Summary for GALNT1

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for GALNT1

Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7.

Research Articles on GALNT1

1. We have elucidated a novel miR-30-GALNT1/2 axis whose dysregulation increases the proportion of inactive proBNP secreted by the heart and impairs the compensatory actions of BNP during the progression of heart failure.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GALNT1 recombinant protein

 Reference Product  PubMed Publications
 MUC1 recombinant protein  >1 publications with GALNT1 and MUC1

Pathways associated with GALNT1 recombinant protein

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Mucin Type O-Glycan Biosynthesis Pathway antibodies  Mucin Type O-Glycan Biosynthesis Pathway Diagram
 Mucin Type O-Glycan Biosynthesis Pathway antibodies  Mucin Type O-Glycan Biosynthesis Pathway Diagram
 O-glycan Biosynthesis, Mucin Type Core Pathway antibodies  O-glycan Biosynthesis, Mucin Type Core Pathway Diagram
 O-glycan Biosynthesis, Mucin Type Core Pathway antibodies  O-glycan Biosynthesis, Mucin Type Core Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 O-linked Glycosylation Of Mucins Pathway antibodies  O-linked Glycosylation Of Mucins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Mucin Core 1 And Core 2 O-glycosylation Pathway antibodies  Mucin Core 1 And Core 2 O-glycosylation Pathway Diagram

Diseases associated with GALNT1 recombinant protein

 Disease Name  Pubmed Publications
 Ovarian Neoplasms Antibodies  >2 publications with GALNT1 and Ovarian Neoplasms
 Ovarian Diseases Antibodies  >2 publications with GALNT1 and Ovarian Diseases
 Inflammation Antibodies  >1 publications with GALNT1 and Inflammation

Organs/Tissues associated with GALNT1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bladder Antibodies  >3 publications with GALNT1 and Bladder
 Ovary Antibodies  >1 publications with GALNT1 and Ovary
 Blood Antibodies  >1 publications with GALNT1 and Blood
 Eye Antibodies  >1 publications with GALNT1 and Eye
 Bone Antibodies  >1 publications with GALNT1 and Bone
 Skin Antibodies  >1 publications with GALNT1 and Skin
 Muscle Antibodies  >1 publications with GALNT1 and Muscle
 Prostate Antibodies  >1 publications with GALNT1 and Prostate
 Uterus Antibodies  >1 publications with GALNT1 and Uterus
 Placenta Antibodies  >1 publications with GALNT1 and Placenta
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000