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Ras and Rab Interactor 1 (RIN1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1383840

MBS1383840 is a recombinant protein targeting Rin1. Also known as Recombinant Mouse Ras and Rab interactor 1 (Rin1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1630 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ras and Rab interactor 1 (Rin1), Recombinant Protein
Full Product Name
Recombinant Mouse Ras and Rab interactor 1 (Rin1)
Product Gene Name
Rin1 recombinant protein
Product Synonym Gene Name
Rin1
Sequence
MEDPGETGAH PLGATNLNFV PGHQQKEKPS TDPLYDTPDT RGVQAGGSQQ PARTVSLRER LLITRPVWLQ LRANAAAALH VLRTEPPGTF LVRKSNTRQC QALCVRLPEA SGPSFVSSHY IEESTGGVSL EGSELMFQDL VQLICGYCRT RAIHQAATHK ELEAISHLGM EFWSSSLNTK DQQRPSEAPP IPRLKARSPQ ELDQGTGAAL CFFNPLFPGD LGPTKREKFK RSFKVRVSTE TSSPLSPPAV PPPPVPVLPG TSSSQTERLP PRQLLQRESS VGYRVPGSAA SPCLPPLPSL QEVDCCSPSS SEEEGSSGSP TTSPRLSRPR HRRPLLRSMS SAFCSLLAPE RQVGRAATML MQNRYTAVGQ LVQDLLTQVR AGPEPRELQG IRQALSRARA MLSAELGPEK LLPPERLELV LEKSLHRSVL KPLRPILAAR LRRRLSADGS LGRLAEGFRL ARTQGPGAFG SHLTLSSPVE TEQVRQKLLQ LLRAYSPSAQ VKWLLQACKL LYTALKSQAG ENAGADEFLP LLSLVLAQCD LPDLLLEAEY MSELLEPTLL TGEGGYYLTS LSASLALLSG LSQARALPLS PAQELQRSLA LWEQRRLPAT HSFQHLLRVA YQDPSTGCTS KTLAVPPGSS IATLSQLCAT KFRVTQPDAF GLFLYKDQGY HRLPPEALAH RLPATGYLIY RRAERPETQG AVAEKAKTGS KGPEAGAWEE ETGGLNREGK PRIAVDQEGK DQARGGHIGP EEQKAEGSQA LEE
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
83,014 Da
Sequence Positions
1-763, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q921Q7
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Rin1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Rin1. It may not necessarily be applicable to this product.

NCBI GI #
21703974
NCBI GeneID
225870
NCBI Accession #
NP_663470.1
UniProt Primary Accession #
Q921Q7
UniProt Related Accession #
Q921Q7
GenBank Nucleotide #
NM_145495.2
NCBI Official Full Name
ras and Rab interactor 1
NCBI Official Synonym Full Names
Ras and Rab interactor 1
NCBI Official Symbol
Rin1
UniProt Protein Name
Ras and Rab interactor 1
UniProt Synonym Protein Names
Ras interaction/interference protein 1
Protein Family
Ras and Rab interactor
UniProt Gene Name
Rin1
NCBI Protein Information
ras and Rab interactor 1

UniProt Comments for Rin1

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis ().
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Research Articles on Rin1

1. BCR-ABL1 kinase activity is regulated by RIN1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Rin1 recombinant protein

 Reference Product  PubMed Publications
 Egfr recombinant protein  >7 publications with Rin1 and Egfr
 Abl1 recombinant protein  >2 publications with Rin1 and Abl1
 Epha4 recombinant protein  >1 publications with Rin1 and Epha4

Pathways associated with Rin1 recombinant protein

 Products by Pathway  Pathway Diagram
 XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies  XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram

Diseases associated with Rin1 recombinant protein

 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >3 publications with Rin1 and Lung Neoplasms
 Disease Models, Animal Antibodies  >3 publications with Rin1 and Disease Models, Animal
 Breast Neoplasms Antibodies  >3 publications with Rin1 and Breast Neoplasms
 Brain Diseases Antibodies  >2 publications with Rin1 and Brain Diseases
 Neoplasms, Experimental Antibodies  >2 publications with Rin1 and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >2 publications with Rin1 and Nervous System Diseases
 Poisoning Antibodies  >1 publications with Rin1 and Poisoning
 Uterine Cervical Neoplasms Antibodies  >1 publications with Rin1 and Uterine Cervical Neoplasms
 Neurotoxicity Syndromes Antibodies  >1 publications with Rin1 and Neurotoxicity Syndromes
 Carcinoma, Hepatocellular Antibodies  >1 publications with Rin1 and Carcinoma, Hepatocellular

Organs/Tissues associated with Rin1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with Rin1 and Brain
 Blood Antibodies  >3 publications with Rin1 and Blood
 Lung Antibodies  >3 publications with Rin1 and Lung
 Bone Marrow Antibodies  >2 publications with Rin1 and Bone Marrow
 Bone Antibodies  >2 publications with Rin1 and Bone
 Thymus Antibodies  >1 publications with Rin1 and Thymus
 Mammary Gland Antibodies  >1 publications with Rin1 and Mammary Gland
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