• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13 (ADAMTS13) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1385749

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a… More details

$405 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
A disintegrin and metalloproteinase with thrombospondin motifs 13 (Adamts13), Recombinant Protein
Full Product Name
Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 13 (Adamts13) , partial
Product Gene Name
Adamts13 recombinant protein
Product Synonym Gene Name
Adamts13
Sequence
WTPLVGLCSI SCGRGLKELY FLCMDSVLKM PVQEELCGLA SKPPSRWEVC RARPCPARWE TQVLAPCPVT CGGGRVPLSV RCVQLDRGHP ISVPHSKCSP VPKPGSFEDC SPEPCPARWK VLSLGPCSAS CGLGTATQMV ACMQLDQGHD NEVNETFCKA LVRPQASVPC LIADCAFRWH ISAWTECSVS CGDGIQRRHD TCLGPQAQVP VPANFCQHLP KPMTVRGCWA GPCA
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
32.7 kDa
Sequence Positions
904-1137aa; partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q769J6
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Adamts13 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Adamts13 purchase

MBS1385749 is a recombinant protein targeting Adamts13. Also known as Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 13 (Adamts13) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Adamts13. It may not necessarily be applicable to this product.

NCBI GI #
47604978
NCBI GeneID
279028
NCBI Accession #
NP_001001322.1
UniProt Primary Accession #
Q769J6
UniProt Secondary Accession #
Q76LW1; A2ALB4
UniProt Related Accession #
Q769J6
GenBank Nucleotide #
NM_001001322.2
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform 1 preproprotein
NCBI Official Synonym Full Names
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
NCBI Official Symbol
Adamts13
NCBI Official Synonym Symbols
Gm710; vWF-CP; ADAM-TS13; ADAMTS-13
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 13
UniProt Synonym Protein Names
von Willebrand factor-cleaving protease; vWF-CP; vWF-cleaving protease
Protein Family
A disintegrin and metalloproteinase with thrombospondin motifs
UniProt Gene Name
Adamts13
UniProt Synonym Gene Names
Gm710; ADAM-TS 13; ADAM-TS13; ADAMTS-13; vWF-CP; vWF-cleaving protease
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 13

NCBI Summary for Adamts13

This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. In certain mouse strains (C57BL/6, for example) an intracisternal A-type particle (IAP) retrotransposon sequence is located in the intron 23 that causes an alternate splicing event resulting in a shorter transcript variants encoding shorter isoforms. The encoded preproprotein undergoes proteolytic processing to generate an active enzyme that cleaves von Willebrand factor (VWF) in circulating blood. [provided by RefSeq, Jul 2016]
Show more

UniProt Comments for Adamts13

Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation.

Research Articles on Adamts13

1. Adamts13 deficiency in obese mice promotes hepatic microthrombosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Adamts13 recombinant protein

 Reference Product  PubMed Publications
 Vwf recombinant protein  >597 publications with Adamts13 and Vwf
 Tsr2 recombinant protein  >3 publications with Adamts13 and Tsr2
 Furin recombinant protein  >3 publications with Adamts13 and Furin
 Pofut2 recombinant protein  >1 publications with Adamts13 and Pofut2

Pathways associated with Adamts13 recombinant protein

 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-glycosylation Of TSR Domain-containing Proteins Pathway antibodies  O-glycosylation Of TSR Domain-containing Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram

Diseases associated with Adamts13 recombinant protein

 Disease Name  Pubmed Publications
 Purpura, Thrombotic Thrombocytopenic Antibodies  >940 publications with Adamts13 and Purpura, Thrombotic Thrombocytopenic
 Thrombotic Microangiopathies Antibodies  >865 publications with Adamts13 and Thrombotic Microangiopathies
 Kidney Diseases Antibodies  >228 publications with Adamts13 and Kidney Diseases
 Purpura, Thrombocytopenic, Idiopathic Antibodies  >161 publications with Adamts13 and Purpura, Thrombocytopenic, Idiopathic
 Inflammation Antibodies  >75 publications with Adamts13 and Inflammation
 Fever Antibodies  >66 publications with Adamts13 and Fever
 Liver Diseases Antibodies  >44 publications with Adamts13 and Liver Diseases
 Disease Models, Animal Antibodies  >33 publications with Adamts13 and Disease Models, Animal
 Necrosis Antibodies  >23 publications with Adamts13 and Necrosis
 Liver Failure Antibodies  >21 publications with Adamts13 and Liver Failure

Organs/Tissues associated with Adamts13 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >637 publications with Adamts13 and Blood
 Liver Antibodies  >70 publications with Adamts13 and Liver
 Kidney Antibodies  >68 publications with Adamts13 and Kidney
 Brain Antibodies  >33 publications with Adamts13 and Brain
 Connective Tissue Antibodies  >9 publications with Adamts13 and Connective Tissue
 Ovary Antibodies  >4 publications with Adamts13 and Ovary
 Intestine Antibodies  >3 publications with Adamts13 and Intestine
 Nerve Antibodies  >2 publications with Adamts13 and Nerve
 Placenta Antibodies  >1 publications with Adamts13 and Placenta
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000