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Mrna Export Factor (RAE1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1386456

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. This protein is a… More details

$1090 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
mRNA export factor (Rae1), Recombinant Protein
Full Product Name
Recombinant Mouse mRNA export factor (Rae1)
Product Gene Name
Rae1 recombinant protein
Product Synonym Gene Name
Rae1
Sequence
MSLFGSTSGF GTGGTSMFGS TTTDNHNPMK DIEVTSSPDD SIGCLSFSPP TLPGNFLIAG SWANDVRCWE VQDSGQTIPK AQQMHTGPVL DVCWSDDGSK VFTASCDKTA KMWDLNSNQA IQIAQHDAPV KTIHWIKAPN YSCVMTGSWD KTLKFWDTRS SNPMMVLQLP ERCYCADVIY PMAVVATAER GLIVYQLENQ PSEFRRIESP LKHQHRCVAI FKDKQNKPTG FALGSIEGRV AIHYINPPNP AKDNFTFKCH RSNGTNTSAP QDIYAVNGIA FHPVHGTLAT VGSDGRFSFW DKDARTKLKT SEQLDQPIAA CCFNHNGNIF AYASSYDWSK GHEFYNPQKK NYIFLRNAAE ELKPRNKK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
40,965 Da
Sequence Positions
1-368, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8C570
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Rae1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rae1 purchase

MBS1386456 is a recombinant protein targeting Rae1. Also known as Recombinant Mouse mRNA export factor (Rae1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Rae1. It may not necessarily be applicable to this product.

NCBI GI #
28201956
NCBI GeneID
66679
NCBI Accession #
NP_780321.1
UniProt Primary Accession #
Q8C570
UniProt Secondary Accession #
Q3UKD4
UniProt Related Accession #
Q8C570
GenBank Nucleotide #
NM_175112.5
NCBI Official Full Name
mRNA export factor
NCBI Official Synonym Full Names
ribonucleic acid export 1
NCBI Official Symbol
Rae1
NCBI Official Synonym Symbols
MNRP; MNRP41; D2Ertd342e; 3230401I12Rik
UniProt Protein Name
mRNA export factor
UniProt Synonym Protein Names
Rae1 protein homolog; mRNA-associated protein mrnp 41
Protein Family
Poly(A)+ RNA export protein
UniProt Gene Name
Rae1
UniProt Synonym Gene Names
Mrnp41
NCBI Protein Information
mRNA export factor

UniProt Comments for Rae1

Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.

Research Articles on Rae1

1. The authors observed that the mouse cytomegalovirus encoded protein m18 is necessary and sufficient to drive expression of the RAE-1 family of NKG2D ligands. RAE-1 is transcriptionally repressed by histone deacetylase inhibitor 3 (HDAC3) in healthy cells, and m18 relieves this repression by directly interacting with Casein Kinase II and preventing it from activating HDAC3.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Rae1 recombinant protein

 Reference Product  PubMed Publications
 Nup98 recombinant protein  >26 publications with Rae1 and Nup98
 Nxf1 recombinant protein  >5 publications with Rae1 and Nxf1
 Nup153 recombinant protein  >3 publications with Rae1 and Nup153
 Nup88 recombinant protein  >2 publications with Rae1 and Nup88
 Nup62 recombinant protein  >1 publications with Rae1 and Nup62

Pathways associated with Rae1 recombinant protein

 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Glucose Transport Pathway antibodies  Glucose Transport Pathway Diagram
 Hexose Transport Pathway antibodies  Hexose Transport Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram

Diseases associated with Rae1 recombinant protein

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >11 publications with Rae1 and Disease Models, Animal
 Inflammation Antibodies  >9 publications with Rae1 and Inflammation
 Neoplasms, Experimental Antibodies  >7 publications with Rae1 and Neoplasms, Experimental
 Liver Diseases Antibodies  >6 publications with Rae1 and Liver Diseases
 Necrosis Antibodies  >5 publications with Rae1 and Necrosis
 Kidney Diseases Antibodies  >3 publications with Rae1 and Kidney Diseases
 Liver Cirrhosis Antibodies  >2 publications with Rae1 and Liver Cirrhosis
 Prostatic Neoplasms Antibodies  >2 publications with Rae1 and Prostatic Neoplasms
 Prostatic Diseases Antibodies  >2 publications with Rae1 and Prostatic Diseases
 Drug-Induced Liver Injury Antibodies  >2 publications with Rae1 and Drug-Induced Liver Injury

Organs/Tissues associated with Rae1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >47 publications with Rae1 and Blood
 Liver Antibodies  >9 publications with Rae1 and Liver
 Spleen Antibodies  >6 publications with Rae1 and Spleen
 Brain Antibodies  >6 publications with Rae1 and Brain
 Kidney Antibodies  >5 publications with Rae1 and Kidney
 Skin Antibodies  >3 publications with Rae1 and Skin
 Muscle Antibodies  >3 publications with Rae1 and Muscle
 Pancreas Antibodies  >3 publications with Rae1 and Pancreas
 Lung Antibodies  >3 publications with Rae1 and Lung
 Intestine Antibodies  >2 publications with Rae1 and Intestine
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