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WAS/WASL-Interacting Protein Family Member 1 (WIPF1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1391113

This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive… More details

$1285 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WAS/WASL-interacting protein family member 1 (Wipf1), Recombinant Protein
Full Product Name
Recombinant Rat WAS/WASL-interacting protein family member 1 (Wipf1)
Product Gene Name
Wipf1 recombinant protein
Product Synonym Gene Name
Wipf1
Sequence
MPVPPPPAPP PPPTFALANT EKPSLNKTEQ AGRNALLSDI SKGKKLKKTV TNDRSAPILD KPKGAGGGYG GGSGGGGGGG SSGGGGNFGG GGPPGLGGLF QAGMPKLRST ANRDNDSGGS RPPILPPGGR ATSAKPFSSP SGPGRFPAPS PGHRSGPPEP PRNRMPPPRP DVGSKPDSLP PPVPNTPRPI PSSLHNRGSP AGLGAPRPPF PGNRGAAFGA GSVRQNLSSS SSPFPRPPLP PTPSRALDDK PPPPPPPVGN RPSMHREAVP PPPSQNSKPP VPSTPRPGAG SQAPPPPPPS RPGPPPLPPT SSDEIPRLPQ RNLSLTSPTP PLPSPGRSGP LPPPPTERPP PPVRDPPGRS GPLPPPPPIN RNGSTARALP ATPQLPSRSG MDSPRSGPRP PLPPDRPGAG APPPPPPSTS VRNGFQDSSC EDEWESRFYF HPISDLPPPE PYVPTTKTYP SKVARSESRS GSNRRERGAP PLPPIPR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
49,751 Da
Sequence Positions
1-487, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q6IN36
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Wipf1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Wipf1 purchase

MBS1391113 is a recombinant protein targeting Wipf1. Also known as Recombinant Rat WAS/WASL-interacting protein family member 1 (Wipf1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Wipf1. It may not necessarily be applicable to this product.

NCBI GI #
48675858
NCBI GeneID
117538
NCBI Accession #
NP_476540.2
UniProt Primary Accession #
Q6IN36
UniProt Secondary Accession #
Q8VDA4
UniProt Related Accession #
Q6IN36
GenBank Nucleotide #
NM_057192.2
NCBI Official Full Name
WAS/WASL-interacting protein family member 1
NCBI Official Synonym Full Names
WAS/WASL interacting protein family, member 1
NCBI Official Symbol
Wipf1
NCBI Official Synonym Symbols
Wip; Waspip
UniProt Protein Name
WAS/WASL-interacting protein family member 1
UniProt Synonym Protein Names
Wiskott-Aldrich syndrome protein-interacting protein; WASP-interacting protein
Protein Family
WAS/WASL-interacting protein family
UniProt Gene Name
Wipf1
UniProt Synonym Gene Names
Waspip; Wip; WASP-interacting protein
NCBI Protein Information
WAS/WASL-interacting protein family member 1

NCBI Summary for Wipf1

binds the rat Wiskott-Aldrich syndrome protein homolog; may mediate mobilization of actin from stress fibers to form new actin filaments [RGD, Feb 2006]

UniProt Comments for Wipf1

Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. Plays a role in the formation of cell ruffles (). May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation.
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Research Articles on Wipf1

1. WASP-interacting protein recognition motifs are required for a functional interaction with N-WASP

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Wipf1 recombinant protein

 Products by Pathway  Pathway Diagram
 T Cell Receptor Signaling Pathway antibodies  T Cell Receptor Signaling Pathway Diagram

Diseases associated with Wipf1 recombinant protein

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with Wipf1 and Breast Neoplasms
 Brain Diseases Antibodies  >2 publications with Wipf1 and Brain Diseases
 Heart Defects, Congenital Antibodies  >1 publications with Wipf1 and Heart Defects, Congenital
 Seizures Antibodies  >1 publications with Wipf1 and Seizures
 Congenital Abnormalities Antibodies  >1 publications with Wipf1 and Congenital Abnormalities
 Inflammation Antibodies  >1 publications with Wipf1 and Inflammation

Organs/Tissues associated with Wipf1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with Wipf1 and Brain
 Embryonic Tissue Antibodies  >1 publications with Wipf1 and Embryonic Tissue
 Spleen Antibodies  >1 publications with Wipf1 and Spleen
 Lung Antibodies  >1 publications with Wipf1 and Lung
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