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Melanoma-Associated Antigen D2 (MAGED2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1391389

This gene is a member of the MAGED gene family. While the MAGEA and MAGEB genes are silent in normal tissues with the exception of testis and placenta, the MAGED genes are expressed ubiquitously. The MAGED genes are clustered on chromosome Xp11. This gene is… More details

$1410 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Melanoma-associated antigen D2 (MAGED2), Recombinant Protein
Full Product Name
Recombinant Human Melanoma-associated antigen D2 (MAGED2)
Product Synonym Gene Name
MAGED2
Sequence
SDTSESGAGL TRFQAEASEK DSSSMMQTLL TVTQNVEVPE TPKASKALEV SEDVKVSKAS GVSKATEVSK TPEAREAPAT QASSTTQLTD TQVLAAENKS LAADTKKQNA DPQAVTMPAT ETKKVSHVAD TKVNTKAQET EAAPSQAPAD EPEPESAAAQ SQENQDTRPK VKAKKARKVK HLDGEEDGSS DQSQASGTTG GRRVSKALMA SMARRASRGP IAFWARRASR TRLAAWARRA LLSLRSPKAR RGKARRRAAK LQSSQEPEAP PPRDVALLQG RANDLVKYLL AKDQTKIPIK RSDMLKDIIK EYTDVYPEII ERAGYSLEKV FGIQLKEIDK NDHLYILLST LEPTDAGILG TTKDSPKLGL LMVLLSIIFM NGNRSSEAVI WEVLRKLGLR PGIHHSLFGD VKKLITDEFV KQKYLDYARV PNSNPPEYEF FWGLRSYYET SKMKVLKFAC KVQKKDPKEW AAQYREAMEA DLKAAAEAAA EAKARAEIRA RMGIGLGSEN AAGPCNWDEA DIGPWAKARI QAGAEAKAKA QESGSASTGA STSTNNSASA SASTSGGFSA GASLTATLTF GLFAGLGGAG ASTSGSSGAC GFSYK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
63,167 Da
Sequence Positions
2-606, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
300470
3D Structure
ModBase 3D Structure for Q9UNF1
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MAGED2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAGED2 purchase

MBS1391389 is a recombinant protein targeting MAGED2. Also known as Recombinant Human Melanoma-associated antigen D2 (MAGED2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for MAGED2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
melanoma-associated antigen D2
NCBI Official Synonym Full Names
MAGE family member D2
NCBI Official Symbol
MAGED2
NCBI Official Synonym Symbols
11B6; BCG1; BCG-1; HCA10; BARTS5; MAGE-D2
UniProt Protein Name
Melanoma-associated antigen D2
UniProt Synonym Protein Names
11B6; Breast cancer-associated gene 1 protein; BCG-1; Hepatocellular carcinoma-associated protein JCL-1; MAGE-D2 antigen
UniProt Gene Name
MAGED2
UniProt Synonym Gene Names
BCG1; BCG-1
NCBI Protein Information
melanoma-associated antigen D2

NCBI Summary for MAGED2

This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID). Mutations in this gene cause a form of transient antenatal Bartter's syndrome. This gene may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by this gene is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
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UniProt Comments for MAGED2

Regulates the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MAGED2 recombinant protein

 Reference Product  PubMed Publications
 MAGED1 recombinant protein  >1 publications with MAGED2 and MAGED1
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