• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Transcription Factor CP2-Like Protein 1 (TCFCP2L1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1394739

MBS1394739 is a recombinant protein targeting Tcfcp2l1. Also known as Recombinant Mouse Transcription factor CP2-like protein 1 (Tcfcp2l1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1260 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Transcription factor CP2-like protein 1 (Tcfcp2l1), Recombinant Protein
Full Product Name
Recombinant Mouse Transcription factor CP2-like protein 1 (Tcfcp2l1)
Product Gene Name
Tcfcp2l1 recombinant protein
Product Synonym Gene Name
Tcfcp2l1
Sequence
MLFWHTQPEH YNQHNSGSYL RDVLALPIFK QEEPQLSPEN GARLPPLQYV LCAATSPAVK LHEETLTYLN QGQSYEIRLL ENRKLGDFQD LNTKYVKSII RVVFHDRRLQ YTEYQQLEGW RWSRPGDRIL DIDIPLSVGI LDPRASPTQL NAVEFLWDPS KRASAFIQVH CISTEFTPRK HGGEKGVPFR VQIDTFKQNE SGDYSEHLHS ASCQIKVFKP KGADRKQKTD REKMEKRTAQ EKEKYQPSYE TTILTECSPW PDVPYQANNT PSPSYNGSPN SFGLREGNSS PNHPVEPLPL GSDHLLPSAS IQDAQQWLHR NRFSQFCWLF ASFSGADLLK MSRDDLVQVC GPADGIRLFN AIKGRNVRPK MTIYVCQELE QNQLPLPQKQ DDSGDNSLCV YHAIFLEELT TLELTEKIAS LYSIPPQHIH RVYRQGPAGI HVVVSNEMVQ NFQDESCFIL STLKAESNDG YHIILKCGL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
54,737 Da
Sequence Positions
1-479, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q3UNW5
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Tcfcp2l1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Tcfcp2l1. It may not necessarily be applicable to this product.

NCBI GI #
134053939
NCBI GeneID
81879
NCBI Accession #
NP_076244.2
UniProt Primary Accession #
Q3UNW5
UniProt Secondary Accession #
Q14AW3; Q99PF2
UniProt Related Accession #
Q3UNW5
GenBank Nucleotide #
NM_023755.2
NCBI Official Full Name
transcription factor CP2-like protein 1
NCBI Official Synonym Full Names
transcription factor CP2-like 1
NCBI Official Symbol
Tfcp2l1
NCBI Official Synonym Symbols
Cp2l1; LBP-9; Crtr-1; AA575098; Tcfcp2l1; 1810030F05Rik; 4932442M07Rik; D930018N21Rik
UniProt Protein Name
Transcription factor CP2-like protein 1
UniProt Synonym Protein Names
CP2-related transcriptional repressor 1; CRTR-1
UniProt Gene Name
Tfcp2l1
UniProt Synonym Gene Names
Crtr1; Tcfcp2l1; CRTR-1
NCBI Protein Information
transcription factor CP2-like protein 1

UniProt Comments for Tcfcp2l1

Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs) (PubMed:23942233, PubMed:26321140). With Klf2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/Stat3 and Wnt/beta-catenin signaling (PubMed:23942238, PubMed:23942233, PubMed:26321140). Required for normal duct development in the salivary gland and kidney (PubMed:17079272). Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (PubMed:28577314). Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, Oxgr1, Ca12, Slc4a1, Aqp6 and IC-specific transcription factor Foxi1 (PubMed:28577314). Regulates also the expression of Jag1 and subsequent notch signaling in the collecting duct (PubMed:28577314). Jag1 initiates notch signaling in PCs but inhibits notch signaling in ICs (PubMed:28577314). Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (PubMed:11073954). Modulates the placental expression of CYP11A1 ().
Show more

Research Articles on Tcfcp2l1

1. TFCP2L1 depends on its N-terminus and CP2-like domain to maintain the undifferentiated state of mouse embryonic stem cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Tcfcp2l1 recombinant protein

 Products by Pathway  Pathway Diagram
 PluriNetWork Pathway antibodies  PluriNetWork Pathway Diagram

Diseases associated with Tcfcp2l1 recombinant protein

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >2 publications with Tcfcp2l1 and Breast Neoplasms
 Mammary Neoplasms, Animal Antibodies  >1 publications with Tcfcp2l1 and Mammary Neoplasms, Animal
 Disease Models, Animal Antibodies  >1 publications with Tcfcp2l1 and Disease Models, Animal
 Kidney Diseases Antibodies  >1 publications with Tcfcp2l1 and Kidney Diseases
 Adenocarcinoma Antibodies  >1 publications with Tcfcp2l1 and Adenocarcinoma

Organs/Tissues associated with Tcfcp2l1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >5 publications with Tcfcp2l1 and Kidney
 Embryonic Tissue Antibodies  >4 publications with Tcfcp2l1 and Embryonic Tissue
 Thyroid Antibodies  >2 publications with Tcfcp2l1 and Thyroid
 Salivary Gland Antibodies  >1 publications with Tcfcp2l1 and Salivary Gland
 Lung Antibodies  >1 publications with Tcfcp2l1 and Lung
 Liver Antibodies  >1 publications with Tcfcp2l1 and Liver
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000