• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Proteasomal Ubiquitin Receptor ADRM1 (ADRM1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1401437

This protein is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript… More details

$1145 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Proteasomal ubiquitin receptor ADRM1 (Adrm1), Recombinant Protein
Full Product Name
Recombinant Mouse Proteasomal ubiquitin receptor ADRM1 (Adrm1)
Product Gene Name
Adrm1 recombinant protein
Product Synonym Gene Name
Adrm1
Sequence
TTSGALFPSL VPGSRGSSTK YLVEFRAGKM SLKGTTVTPD KRKGLVYIQQ TDDSLIHFCW KDRTSGTVED DLIIFPDDCE FKRVPQCPSG RVYVLKFKAG SKRLFFWMQE PKTDQDEEHC RKVNECLNNP PMPGSLGASG SSGHELSALG GEGGLQSLLG NMSHSQLMQL IGPAGLGGLG GLGALTGPGL ASLLGSSGPP ASSSSSSSRS QSAAVTPSSS TSSARATPAP SAPAAASATS PSPAPSSGNG TSTAASPTQP IQLSDLQSIL ATMNVPAGPG GSQQVDLASV LTPEIMAPIL ANADVQERLL PYLPSGESLP QTADEIQNTL TSPQFQQALG MFSAALASGQ LGPLMCQFGL PAEAVEAANK GDVEAFAKAM QNNAKSDPKE GDTKDKKDEE EDMSLD
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
42,060 Da
Sequence Positions
2-407, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9JKV1
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Adrm1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Adrm1 purchase

MBS1401437 is a recombinant protein targeting Adrm1. Also known as Recombinant Mouse Proteasomal ubiquitin receptor ADRM1 (Adrm1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Adrm1. It may not necessarily be applicable to this product.

NCBI GI #
31981027
NCBI GeneID
56436
NCBI Accession #
NP_062796.2
UniProt Primary Accession #
Q9JKV1
UniProt Secondary Accession #
Q3UKZ8; Q8BPH8; Q922A7
UniProt Related Accession #
Q9JKV1
GenBank Nucleotide #
NM_019822.3
NCBI Official Full Name
proteasomal ubiquitin receptor ADRM1
NCBI Official Synonym Full Names
adhesion regulating molecule 1
NCBI Official Symbol
Adrm1
NCBI Official Synonym Symbols
Arm1; ARM-1; Gp110; Rpn13; AA408205; AU043535; 1110063P18Rik; 2510006J17Rik
UniProt Protein Name
Proteasomal ubiquitin receptor ADRM1
UniProt Synonym Protein Names
110 kDa cell membrane glycoprotein; Gp110; Adhesion-regulating molecule 1; ARM-1; Rpn13 homolog
UniProt Gene Name
Adrm1
UniProt Synonym Gene Names
Gp110; Gp110; ARM-1
NCBI Protein Information
proteasomal ubiquitin receptor ADRM1

UniProt Comments for Adrm1

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and thus activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.
Show more

Research Articles on Adrm1

1. Data show that either Rpn13 knock down or RA190 treatment reduced the capacity of myeloid-derived-suppressor cells (MDSCs) to suppress T cell proliferation in vitro.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Adrm1 recombinant protein

 Products by Pathway  Pathway Diagram
 Targeted Protein Degradation Pathway antibodies  Targeted Protein Degradation Pathway Diagram

Diseases associated with Adrm1 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >9 publications with Adrm1 and Neoplasms
 Neoplasm Metastasis Antibodies  >3 publications with Adrm1 and Neoplasm Metastasis
 Ovarian Neoplasms Antibodies  >2 publications with Adrm1 and Ovarian Neoplasms
 Adenocarcinoma Antibodies  >2 publications with Adrm1 and Adenocarcinoma
 Kidney Neoplasms Antibodies  >2 publications with Adrm1 and Kidney Neoplasms
 Carcinoma, Squamous Cell Antibodies  >2 publications with Adrm1 and Carcinoma, Squamous Cell
 Breast Neoplasms Antibodies  >2 publications with Adrm1 and Breast Neoplasms
 Ataxia Antibodies  >1 publications with Adrm1 and Ataxia
 Skin Diseases Antibodies  >1 publications with Adrm1 and Skin Diseases
 Nervous System Diseases Antibodies  >1 publications with Adrm1 and Nervous System Diseases

Organs/Tissues associated with Adrm1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >2 publications with Adrm1 and Kidney
 Bone Antibodies  >2 publications with Adrm1 and Bone
 Ovary Antibodies  >2 publications with Adrm1 and Ovary
 Pancreas Antibodies  >1 publications with Adrm1 and Pancreas
 Lymph Node Antibodies  >1 publications with Adrm1 and Lymph Node
 Liver Antibodies  >1 publications with Adrm1 and Liver
 Lung Antibodies  >1 publications with Adrm1 and Lung
 Skin Antibodies  >1 publications with Adrm1 and Skin
 Blood Antibodies  >1 publications with Adrm1 and Blood
 Brain Antibodies  >1 publications with Adrm1 and Brain
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000