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Granulocyte Colony Stimulating Factor Biotinylated (GCSF) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140157

Introduction: GCSF is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different isoforms have been found for this… More details

$455 / 0.5 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Granulocyte Colony Stimulating Factor Biotinylated (GCSF), Monoclonal Antibody
Full Product Name
Mouse Anti Human Granulocyte Colony Stimulating Factor Biotinylated
Product Gene Name
anti-GCSF antibody
Product Synonym Names
G CSF Antibody, Biotin; Granulocyte Colony Stimulating Factor, Mouse Anti-Human, Biotin; CSF-3; MGI-1G; GM-CSF beta; Pluripoietin; Filgrastim; Lenograstim; G-CSF; MGC45931; GCSF; GCSF Biotin
Clonality
Monoclonal
Isotype
IgG
Clone Number
NYRhGCSF
Host
Mouse
Purity/Purification
Protein A.
Concentration
1 mg/ml in PBS (after reconstitution). (lot specific)
Preparation and Storage
In lyophilized form, for long periods, store at 4 degree C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
Antibody is shipped lyophilized at ambient temperature.
Molecular Weight
18,434 Da
OMIM
138970
Reconstitution
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Immunogen
r.Human G-CSF.

Product Categories/Family for anti-GCSF antibody

Anti-Human CYTOKINES; Monoclonal Antibodies; Anti Human Cytokine
Applications Tested/Suitable for anti-GCSF antibody
ELISA (EIA), Western Blot (WB), Intra-cellular staining
Application Notes for anti-GCSF antibody
Direct ELISA, Western Blot, Intra-cellular staining.
For intra-cellular staining use 10 ul per 1,000,000 cells.

Other Notes

Small volumes of anti-GCSF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GCSF purchase

MBS140157 is an antibody targeting GCSF. Also known as Mouse Anti Human Granulocyte Colony Stimulating Factor Biotinylated. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GCSF. It may not necessarily be applicable to this product.

NCBI GI #
27437049
NCBI GeneID
1440
NCBI Accession #
NP_757373.1
UniProt Secondary Accession #
A8MXR7
UniProt Related Accession #
P09919
GenBank Nucleotide #
NM_172219.2
NCBI Official Full Name
granulocyte colony-stimulating factor isoform b
NCBI Official Synonym Full Names
colony stimulating factor 3 (granulocyte)
NCBI Official Symbol
CSF3
NCBI Official Synonym Symbols
GCSF; CSF3OS; C17orf33
UniProt Protein Name
Granulocyte colony-stimulating factor
UniProt Synonym Protein Names
Pluripoietin; INN: Filgrastim; INN: Lenograstim
UniProt Gene Name
CSF3
UniProt Synonym Gene Names
C17orf33; GCSF; G-CSF
UniProt Entry Name
CSF3_HUMAN
NCBI Protein Information
granulocyte colony-stimulating factor; filgrastim; granulocyte-colony stimulating factor; lenograstim; pluripoietin

NCBI Summary for GCSF

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]

UniProt Comments for GCSF

G-CSF: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Cell cycle regulation; Cytokine; Secreted

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular space

Molecular Function: enzyme binding; growth factor activity; cytokine activity; granulocyte colony-stimulating factor receptor binding

Biological Process: granulocyte differentiation; positive regulation of myeloid cell differentiation; positive regulation of protein binding; multicellular organismal development; cytokine and chemokine mediated signaling pathway; positive regulation of peptidyl-serine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of actin filament polymerization; positive regulation of cell proliferation; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter; immune response
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Research Articles on GCSF

1. G-CSF constrains cancer to grow and progress by, respectively, supporting the survival of sympathetic nerve fibers in 6-hydroxydopamine-sympathectomized mice.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GCSF antibody

 Reference Product  PubMed Publications
 CSF3R antibody  >14 publications with GCSF and CSF3R
 MMP9 antibody  >7 publications with GCSF and MMP9
 IL10 antibody  >6 publications with GCSF and IL10
 CXCL12 antibody  >4 publications with GCSF and CXCL12
 ERBB2 antibody  >2 publications with GCSF and ERBB2
 STAT3 antibody  >2 publications with GCSF and STAT3
 SELL antibody  >1 publications with GCSF and SELL
 CXCR4 antibody  >1 publications with GCSF and CXCR4

Pathways associated with anti-GCSF antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram

Diseases associated with anti-GCSF antibody

 Disease Name  Pubmed Publications
 Disease Susceptibility Antibodies  >6 publications with GCSF and Disease Susceptibility
 Nervous System Diseases Antibodies  >5 publications with GCSF and Nervous System Diseases
 Breast Neoplasms Antibodies  >3 publications with GCSF and Breast Neoplasms
 Neutropenia Antibodies  >3 publications with GCSF and Neutropenia
 Leukopenia Antibodies  >2 publications with GCSF and Leukopenia
 Anemia Antibodies  >2 publications with GCSF and Anemia
 Neoplasm Metastasis Antibodies  >2 publications with GCSF and Neoplasm Metastasis
 Leukemia, Myeloid, Acute Antibodies  >2 publications with GCSF and Leukemia, Myeloid, Acute
 Peripheral Nervous System Diseases Antibodies  >1 publications with GCSF and Peripheral Nervous System Diseases
 Pulmonary Fibrosis Antibodies  >1 publications with GCSF and Pulmonary Fibrosis

Organs/Tissues associated with anti-GCSF antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >7 publications with GCSF and Skin
 Muscle Antibodies  >5 publications with GCSF and Muscle
 Lung Antibodies  >5 publications with GCSF and Lung
 Brain Antibodies  >3 publications with GCSF and Brain
 Liver Antibodies  >2 publications with GCSF and Liver
 Uterus Antibodies  >2 publications with GCSF and Uterus
 Uncharacterized Tissue Antibodies  >1 publications with GCSF and Uncharacterized Tissue
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