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26s Proteasome Non-Atpase Regulatory Subunit 11 (PSMD11) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140209

Introduction: The 26S proteasome is a multicatalytic proteinase complex with a well ordered structure composed of two complexes- a 20S core and a 19S regulator. PSMD11 is a non-ATPase subunit of the 19S regulator. The 20S core is composed of four rings of 28… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
26S proteasome non-ATPase regulatory subunit 11 (PSMD11), Monoclonal Antibody
Full Product Name
Mouse Anti Human 26S proteasome non-ATPase regulatory subunit 11
Product Gene Name
anti-PSMD11 antibody
Product Synonym Names
PSMD11 Antibody; 26S proteasome non-ATPase regulatory subunit 11, Mouse Anti Human; 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit p44.5; PSMD11; S9; Rpn6; p44.5; MGC3844
Clonality
Monoclonal
Isotype
IgG1 heavy chain and kappa light chain
Clone Number
PAT1F4AT
Host
Mouse
Form/Format
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Purity/Purification
PSMD11 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
Molecular Weight
47,437 Da
Immunogen
Anti-human PSMD11 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PSMD11 amino acids 1-422 purified from E Coli.

Product Categories/Family for anti-PSMD11 antibody

Monoclonal Antibodies; Anti-Human Enzymes; Monoclonal Antibodies; Anti Human Enzyme
Applications Tested/Suitable for anti-PSMD11 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-PSMD11 antibody
PSMD11 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:250 ~ 1000. Recommended starting dilution is 1:250.

Other Notes

Small volumes of anti-PSMD11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSMD11 purchase

MBS140209 is an antibody targeting PSMD11. Also known as Mouse Anti Human 26S proteasome non-ATPase regulatory subunit 11. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PSMD11. It may not necessarily be applicable to this product.

NCBI GI #
33585718
NCBI GeneID
69077
NCBI Accession #
AAH55457.1
UniProt Related Accession #
Q8BG32
NCBI Official Full Name
Psmd11 protein, partial
NCBI Official Synonym Full Names
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
NCBI Official Symbol
Psmd11
NCBI Official Synonym Symbols
S9; P44.5; C78232; 1700089D09Rik; 1810019E17Rik; 2610024G20Rik; 2810055C24Rik
UniProt Protein Name
26S proteasome non-ATPase regulatory subunit 11
UniProt Synonym Protein Names
26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5
Protein Family
26S proteasome non-ATPase regulatory
UniProt Gene Name
Psmd11
UniProt Entry Name
PSD11_MOUSE
NCBI Protein Information
26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5

UniProt Comments for PSMD11

PSMD11: Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity. Belongs to the proteasome subunit S9 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Proteasome complex; Protease

Cellular Component: proteasome complex; membrane; proteasome regulatory particle; nucleus

Molecular Function: protein binding

Biological Process: ubiquitin-dependent protein catabolic process; stem cell differentiation; proteasome assembly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PSMD11 antibody

 Products by Pathway  Pathway Diagram
 AMER1 Mutants Destabilize The Destruction Complex Pathway antibodies  AMER1 Mutants Destabilize The Destruction Complex Pathway Diagram
 APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway antibodies  APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway Diagram
 APC Truncation Mutants Have Impaired AXIN Binding Pathway antibodies  APC Truncation Mutants Have Impaired AXIN Binding Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies  APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
 APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway antibodies  APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway Diagram
 AUF1 (hnRNP D0) Destabilizes MRNA Pathway antibodies  AUF1 (hnRNP D0) Destabilizes MRNA Pathway Diagram
 AXIN Missense Mutants Destabilize The Destruction Complex Pathway antibodies  AXIN Missense Mutants Destabilize The Destruction Complex Pathway Diagram

Diseases associated with anti-PSMD11 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with PSMD11 and Nervous System Diseases

Organs/Tissues associated with anti-PSMD11 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with PSMD11 and Muscle
 Ovary Antibodies  >1 publications with PSMD11 and Ovary
 Spinal Cord Antibodies  >1 publications with PSMD11 and Spinal Cord
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