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Methionine Adenosyltransferase II Alpha (MAT2A) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140284

Introduction: MAT2A is an important enzyme in cellular metabolism and catalyzes the formation of S-adenosylmethionine (SAMe) from L-methionine and ATP. MAT2A is expressed in extrahepatic tissues. In liver, MAT2A expression associates with growth,… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Methionine Adenosyltransferase II Alpha (MAT2A), Monoclonal Antibody
Full Product Name
Mouse Anti Human Methionine Adenosyltransferase II Alpha
Product Gene Name
Product Synonym Names
MAT2A Antibody; Methionine Adenosyltransferase II Alpha, Mouse Anti Human; MATA2; MATII; SAMS2; MAT-2A; S-adenosylmethionine synthetase isoform type-2; AdoMet synthetase 2; Methionine adenosyltransferase 2; Methionine adenosyltransferase II; MAT2A; AMS2
Clonality
Monoclonal
Isotype
IgG2b heavy chain and kappa light chain
Clone Number
PAT3A2AT
Host
Mouse
Species Reactivity
Human
Form/Format
Sterile filtered colorless solution.
Purity/Purification
MAT2A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Concentration
1mg/ml containing PBS, pH-7.4, & 0.02% Sodium Azide and 10% glycerol. (lot specific)
Preparation and Storage
Short Term: 4°C
Long Term: -20°C
Molecular Weight
32,965 Da
OMIM
601468
Immunogen
Anti-human MAT2A mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human MAT2A amino acids 1-395 purified from E. coli.
Applications Tested/Suitable for anti-MAT2A antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-MAT2A antibody
MAT2A antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Other Notes

Small volumes of anti-MAT2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAT2A purchase

MBS140284 is an antibody targeting MAT2A. Also known as Mouse Anti Human Methionine Adenosyltransferase II Alpha. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MAT2A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
S-adenosylmethionine synthase isoform type-2
NCBI Official Synonym Full Names
methionine adenosyltransferase II, alpha
NCBI Official Symbol
MAT2A
NCBI Official Synonym Symbols
MATA2; MATII; SAMS2
UniProt Protein Name
S-adenosylmethionine synthase isoform type-2
UniProt Synonym Protein Names
Methionine adenosyltransferase 2; MAT 2; Methionine adenosyltransferase II; MAT-II
UniProt Gene Name
MAT2A
UniProt Synonym Gene Names
AMS2; MATA2; AdoMet synthase 2; MAT 2; MAT-II
UniProt Entry Name
METK2_HUMAN
NCBI Protein Information
S-adenosylmethionine synthase isoform type-2; MAT 2; MAT-II; adoMet synthase 2; adoMet synthetase 2; methionine adenosyltransferase 2

NCBI Summary for MAT2A

The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]

UniProt Comments for MAT2A

MAT2A: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. Belongs to the AdoMet synthase family.

Protein type: Transferase; EC 2.5.1.6; Other Amino Acids Metabolism - selenoamino acid; Amino Acid Metabolism - cysteine and methionine

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: methionine adenosyltransferase complex; cytosol

Molecular Function: protein binding; methionine adenosyltransferase activity; metal ion binding; ATP binding

Biological Process: methylation; xenobiotic metabolic process; S-adenosylmethionine biosynthetic process; one-carbon compound metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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