Human CRMP1 Recombinant Protein – Cat# MBS1403925

Dihydropyrimidinase-Related Protein 1 (CRMP1) Human Recombinant Protein

Name: CRMP1 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1403925
Price: 365 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1403925

Necessary for signaling by class 3 saphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May participate in cytokinesis. More details

$365 / 0.02 mg (Yeast) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Dihydropyrimidinase-related protein 1 (CRMP1), Recombinant Protein

Full Product Name

Recombinant Human Dihydropyrimidinase-related protein 1 (CRMP1)

Product Gene Name

CRMP1 recombinant protein

Product Synonym Names

Collapsin response mediator protein 1; CRMP-1; Unc-33-like phosphoprotein 3; ULIP-3

Sequence

MSYQGKKSIP HITSDRLLIK GGRIINDDQS LYADVYLEDG LIKQIGENLI VPGGVKTIEA NGRMVIPGGI DVNTYLQKPS QGMTAADDFF QGTRAALVGG TTMIIDHVVP EPGSSLLTSF EKWHEAADTK SCCDYSLHVD ITSWYDGVRE ELEVLVQDKG VNSFQVYMAY KDVYQMSDSQ LYEAFTFLKG LGAVILVHAE NGDLIAQEQK RILEMGITGP EGHALSRPEE LEAEAVFRAI TIAGRINCPV YITKVMSKSA ADIIALARKK GPLVFGEPIA ASLGTDGTHY WSKNWAKAAA FVTSPPLSPD PTTPDYLTSL LACGDLQVTG SGHCPYSTAQ KAVGKDNFTL IPEGVNGIEE RMTVVWDKAV ATGKMDENQF VAVTSTNAAK IFNLYPRKGR IAVGSDADVV IWDPDKLKTI TAKSHKSAVE YNIFEGMECH GSPLVVISQG KIVFEDGNIN VNKGMGRFIP RKAFPEHLYQ RVKIRNKVFG LQGVSRGMYD GPVYEVPATP KYATPAPSAK SSPSKHQPPP IRNLHQSNFS LSGAQIDDNN PRRTGHRIVA PPGGRSNITS LG

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Molecular Weight

64.2 kDa

Sequence Positions

1-572aa; Full Length Protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

602462

3D Structure

ModBase 3D Structure for Q14194

Production Note

Special Offer: The E. coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E. coli host-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E. coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E. coli host-expressed protein for the fastest delivery among all hosts. Please contact us or email to support@mybiosource.com for more details.

Product Categories/Family for CRMP1 recombinant protein

Neuroscience

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for CRMP1 recombinant protein

A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.Hamajima N., Matsuda K., Sakata S., Tamaki N., Sasaki M., Nonaka M.Gene 180:157-163(1996)

Other Notes

Small volumes of CRMP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRMP1 purchase

MBS1403925 is a recombinant protein targeting CRMP1. Also known as Recombinant Human Dihydropyrimidinase-related protein 1 (CRMP1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for CRMP1. It may not necessarily be applicable to this product.

NCBI GI #

62422571

NCBI GeneID

1400

NCBI Accession #

NP_001014809.1

UniProt Primary Accession #

Q14194

UniProt Secondary Accession #

Q13024; Q4W5F1; Q96TC8; A0EJG6

GenBank Nucleotide #

NM_001014809.2

NCBI Official Full Name

dihydropyrimidinase-related protein 1 isoform 1

NCBI Official Synonym Full Names

collapsin response mediator protein 1

NCBI Official Symbol

CRMP1

NCBI Official Synonym Symbols

DRP1; DRP-1; CRMP-1; DPYSL1; ULIP-3

UniProt Protein Name

Dihydropyrimidinase-related protein 1

UniProt Synonym Protein Names

Collapsin response mediator protein 1; CRMP-1; Unc-33-like phosphoprotein 3; ULIP-3

Protein Family

Dihydropyrimidinase-related protein

UniProt Gene Name

CRMP1

UniProt Synonym Gene Names

DPYSL1; ULIP3; DRP-1; CRMP-1; ULIP-3

UniProt Entry Name

DPYL1_HUMAN

NCBI Summary for CRMP1

This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

UniProt Comments for CRMP1

CRMP-1: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Hydrolase; Cytoskeletal

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: cell soma; cytoplasm; cytosol; dendrite; microtubule organizing center; spindle

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; protein binding

Biological Process: axon guidance; microtubule cytoskeleton organization and biogenesis; nervous system development; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CRMP1 recombinant protein

Reference Product	PubMed Publications
SEMA3A recombinant protein	>17 publications with CRMP1 and SEMA3A
DPYSL3 recombinant protein	>7 publications with CRMP1 and DPYSL3
CDK5 recombinant protein	>7 publications with CRMP1 and CDK5
FYN recombinant protein	>2 publications with CRMP1 and FYN
DPYSL2 recombinant protein	>1 publications with CRMP1 and DPYSL2

Pathways associated with CRMP1 recombinant protein

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
CRMPs In Sema3A Signaling Pathway antibodies	CRMPs In Sema3A Signaling Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Semaphorin Interactions Pathway antibodies	Semaphorin Interactions Pathway Diagram

Diseases associated with CRMP1 recombinant protein

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>7 publications with CRMP1 and Lung Neoplasms
Respiratory Tract Diseases Antibodies	>6 publications with CRMP1 and Respiratory Tract Diseases
Lung Diseases Antibodies	>6 publications with CRMP1 and Lung Diseases
Neoplasm Metastasis Antibodies	>4 publications with CRMP1 and Neoplasm Metastasis
Inflammation Antibodies	>3 publications with CRMP1 and Inflammation
Disease Models, Animal Antibodies	>2 publications with CRMP1 and Disease Models, Animal
Necrosis Antibodies	>2 publications with CRMP1 and Necrosis
Vascular Diseases Antibodies	>1 publications with CRMP1 and Vascular Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with CRMP1 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>1 publications with CRMP1 and Liver Neoplasms

Organs/Tissues associated with CRMP1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>55 publications with CRMP1 and Nerve
Brain Antibodies	>26 publications with CRMP1 and Brain
Lung Antibodies	>10 publications with CRMP1 and Lung
Embryonic Tissue Antibodies	>8 publications with CRMP1 and Embryonic Tissue
Muscle Antibodies	>6 publications with CRMP1 and Muscle
Heart Antibodies	>1 publications with CRMP1 and Heart
Intestine Antibodies	>1 publications with CRMP1 and Intestine
Mammary Gland Antibodies	>1 publications with CRMP1 and Mammary Gland
Testis Antibodies	>1 publications with CRMP1 and Testis
Uncharacterized Tissue Antibodies	>1 publications with CRMP1 and Uncharacterized Tissue