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CDGSH Iron Sulfur Domain 1 (CISD1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140453

Introduction: CISD1 protein holds a CDGSH iron-sulfur domain and is known to bind a redox-active [2Fe-2S] cluster. CISD1 is restricted to the outer membrane of mitochondria and takes part in oxidation regulation. More details

$250 / 0.005 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CDGSH Iron Sulfur Domain 1 (CISD1), Monoclonal Antibody
Full Product Name
Mouse Anti Human CDGSH Iron Sulfur Domain 1
Product Gene Name
Product Synonym Names
CISD1 Antibody; CDGSH Iron Sulfur Domain 1, Mouse Anti Human; CDGSH Iron Sulfur Domain 1; Chromosome 10 Open Reading Frame 70; CDGSH Iron Sulfur Domain-Containing Protein 1; Zinc Finger CDGSH-Type Domain 1; C10orf70; ZCD1; MitoNEET; MDS029
Clonality
Monoclonal
Isotype
IgG1 heavy chain and Kappa light chain
Clone Number
PAT1A8A
Host
Mouse
Form/Format
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Sterile Filtered colorless solution.
Purity/Purification
CISD1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
Molecular Weight
12,199 Da
OMIM
611932
Immunogen
Anti-human CISD1 mAb, clone PAT1A8A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CISD1 protein 32-108 amino acids purified from E Coli.
Applications Tested/Suitable for anti-CISD1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-CISD1 antibody
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Other Notes

Small volumes of anti-CISD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CISD1 purchase

MBS140453 is an antibody targeting CISD1. Also known as Mouse Anti Human CDGSH Iron Sulfur Domain 1. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CISD1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CDGSH iron sulfur domain 1
NCBI Official Synonym Full Names
CDGSH iron sulfur domain 1
NCBI Official Symbol
CISD1
NCBI Official Synonym Symbols
ZCD1; MDS029; C10orf70; mitoNEET
UniProt Protein Name
CDGSH iron-sulfur domain-containing protein 1
UniProt Synonym Protein Names
MitoNEET
UniProt Gene Name
CISD1
UniProt Synonym Gene Names
C10orf70; ZCD1
UniProt Entry Name
CISD1_HUMAN
NCBI Protein Information
CDGSH iron-sulfur domain-containing protein 1; CDGSH iron sulfur domain-containing protein 1; zinc finger CDGSH-type domain 1; zinc finger, CDGSH-type domain 1

NCBI Summary for CISD1

This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012]
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UniProt Comments for CISD1

ZCD1: Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family.

Protein type: Membrane protein, integral; Mitochondrial

Chromosomal Location of Human Ortholog: 10q21.1

Cellular Component: mitochondrial outer membrane; mitochondrion; integral to membrane

Molecular Function: 2 iron, 2 sulfur cluster binding; metal ion binding

Biological Process: regulation of cellular respiration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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