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Calcyclin Binding Protein (CACYBP) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140487

CACYBP (calcyclin binding protein) participates in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. CACYBP acts as a molecular bridge in ubiquitin E3 complexes. CACYBP is involved in the ubiquitin-mediated… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Calcyclin Binding Protein (CACYBP), Monoclonal Antibody
Full Product Name
Mouse Anti Human Calcyclin Binding Protein
Product Gene Name
anti-CACYBP antibody
Product Synonym Names
CACYBP Antibody; Calcyclin Binding Protein, Mouse Anti Human; S100A6BP; S100A6 Binding Protein; GIG5; PNAS-107; RP1-102G20.6; SIP; CACYBP; hCacyBP; Siah-interacting protein; MGC87971
Clonality
Monoclonal
Clone Number
PAT3G8AT
Host
Mouse
Species Reactivity
Human
Form/Format
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Sterile filtered colorless solution.
Purity/Purification
Purified from mouse ascitic fluids by protein-A affinity chromatography
Preparation and Storage
Storage: For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
Stability: 12 months at -20 degree C. 1 month at 4 degree C.
Molecular Weight
21,228 Da
OMIM
606186
Ig Subclass
Mouse IgG2a heavy chain and k light chain.
Immunogen
Anti-human CACYBP mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CACYBP protein 1-185 amino acids purified from E Coli.

Product Categories/Family for anti-CACYBP antibody

Monoclonal/Polyclonal Antibodies
Applications Tested/Suitable for anti-CACYBP antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-CACYBP antibody
CACYBP antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity.

Other Notes

Small volumes of anti-CACYBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CACYBP purchase

MBS140487 is an antibody targeting CACYBP. Also known as Mouse Anti Human Calcyclin Binding Protein. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CACYBP. It may not necessarily be applicable to this product.

NCBI GI #
3063653
NCBI GeneID
27101
NCBI Accession #
AAC21458.1
UniProt Secondary Accession #
O60666; Q5R370; Q5R371; B2ZWH2; B3KSF1
UniProt Related Accession #
Q9HB71
NCBI Official Full Name
calcyclin binding protein
NCBI Official Synonym Full Names
calcyclin binding protein
NCBI Official Symbol
CACYBP
NCBI Official Synonym Symbols
SIP; GIG5; PNAS-107; S100A6BP
UniProt Protein Name
Calcyclin-binding protein
UniProt Synonym Protein Names
S100A6-binding protein; Siah-interacting protein
Protein Family
Calcyclin-binding protein
UniProt Gene Name
CACYBP
UniProt Synonym Gene Names
S100A6BP; SIP; CacyBP; hCacyBP
UniProt Entry Name
CYBP_HUMAN
NCBI Protein Information
calcyclin-binding protein

UniProt Comments for CACYBP

CACYBP: a nuclear/cytoplasmic protein involved in calcium-dependent ubiquitination and proteosomal degradation of target proteins. A possible molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). Interacts with proteins of the S100 family at physiological calcium concentrations. Component of some large E3 complexes and interacts directly with SIAH1, SIAH2 and SKP1A. Cytoplasmic at low calcium concentrations. In neuroblastoma cells, after a retinoic acid (RA) induction and calcium increase, it localizes in both the nucleus and cytoplasm. The nuclear fraction may be phosphorylated. Two alternatively spliced isoforms have been described.

Protein type: Adaptor/scaffold; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 1q24-q25

Cellular Component: beta-catenin destruction complex; cytoplasm; nucleoplasm

Molecular Function: protein binding; protein homodimerization activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CACYBP antibody

 Reference Product  PubMed Publications
 CTNNB1 antibody  >30 publications with CACYBP and CTNNB1
 S100A6 antibody  >24 publications with CACYBP and S100A6
 SKP1 antibody  >18 publications with CACYBP and SKP1
 SIAH1 antibody  >4 publications with CACYBP and SIAH1
 APC antibody  >2 publications with CACYBP and APC
 TBL1X antibody  >2 publications with CACYBP and TBL1X
 GSK3B antibody  >1 publications with CACYBP and GSK3B

Pathways associated with anti-CACYBP antibody

 Products by Pathway  Pathway Diagram
 Gastric Cancer Network 2 Pathway antibodies  Gastric Cancer Network 2 Pathway Diagram
 Wnt Signaling Pathway antibodies  Wnt Signaling Pathway Diagram
 Wnt Signaling Pathway antibodies  Wnt Signaling Pathway Diagram

Diseases associated with anti-CACYBP antibody

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >6 publications with CACYBP and Neoplasm Metastasis
 Nervous System Diseases Antibodies  >6 publications with CACYBP and Nervous System Diseases
 Carcinoma Antibodies  >6 publications with CACYBP and Carcinoma
 Adenocarcinoma Antibodies  >4 publications with CACYBP and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >4 publications with CACYBP and Neoplasms, Experimental
 Kidney Diseases Antibodies  >3 publications with CACYBP and Kidney Diseases
 Disease Models, Animal Antibodies  >3 publications with CACYBP and Disease Models, Animal
 Breast Neoplasms Antibodies  >3 publications with CACYBP and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with CACYBP and Cell Transformation, Neoplastic
 Acute Kidney Injury Antibodies  >1 publications with CACYBP and Acute Kidney Injury

Organs/Tissues associated with anti-CACYBP antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >18 publications with CACYBP and Brain
 Stomach Antibodies  >10 publications with CACYBP and Stomach
 Blood Antibodies  >8 publications with CACYBP and Blood
 Ascites Antibodies  >5 publications with CACYBP and Ascites
 Kidney Antibodies  >4 publications with CACYBP and Kidney
 Lymph Node Antibodies  >4 publications with CACYBP and Lymph Node
 Lymph Antibodies  >4 publications with CACYBP and Lymph
 Nerve Antibodies  >3 publications with CACYBP and Nerve
 Muscle Antibodies  >3 publications with CACYBP and Muscle
 Uterus Antibodies  >2 publications with CACYBP and Uterus
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