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Inhibitor of Growth Family (ING2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140511

Inhibitor of Growth Family, Member 2 (ING2) belongs to the inhibitor of growth (ING) family. ING family members associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and serve in DNA repair and… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Inhibitor of Growth Family (ING2), Monoclonal Antibody
Full Product Name
Mouse Anti Human Inhibitor of Growth Family, Member 2
Product Gene Name
Product Synonym Names
ING2 Antibody; Inhibitor of Growth Family Member 2, Mouse Anti Human; Inhibitor Of Growth Family Member 2; ING1L; Inhibitor Of Growth 1-Like Protein; P33ING2; ING1Lp; P32; Inhibitor Of Growth Family Member 1-Like; Inhibitor Of Growth Protein 2; ING2
Clonality
Monoclonal
Clone Number
PAT39E5AT
Host
Mouse
Species Reactivity
Human
Form/Format
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Sterile filtered colorless solution.
Purity/Purification
Purified from mouse ascitic fluids by protein-A affinity chromatography
Preparation and Storage
Storage: For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
Stability: 12 months at -20 degree C. 1 month at 4 degree C.
Molecular Weight
20,482 Da
OMIM
608524
Ig Subclass
Mouse IgG1 heavy chain and k light chain.
Immunogen
Anti-human ING2 mAb, clone PAT39E5AT, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ING2 protein 1-280 amino acids purified from E Coli.
Applications Tested/Suitable for anti-ING2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-ING2 antibody
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity.

Other Notes

Small volumes of anti-ING2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ING2 purchase

MBS140511 is an antibody targeting ING2. Also known as Mouse Anti Human Inhibitor of Growth Family, Member 2. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ING2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
inhibitor of growth family member 4 variant deltaEx2
NCBI Official Synonym Full Names
inhibitor of growth family member 4
NCBI Official Symbol
ING4
NCBI Official Synonym Symbols
my036; p29ING4
UniProt Protein Name
Inhibitor of growth protein 4
UniProt Synonym Protein Names
p29ING4
UniProt Gene Name
ING4
UniProt Entry Name
ING4_HUMAN
NCBI Protein Information
inhibitor of growth protein 4

UniProt Comments for ING2

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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