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Nudix Type Motif 1 (NUDT1) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140538

MBS140538 is an antibody targeting NUDT1. Also known as Mouse Anti Human Nudix Type Motif 1. More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nudix Type Motif 1 (NUDT1), Antibody
Full Product Name
Mouse Anti Human Nudix Type Motif 1
Product Gene Name
anti-NUDT1 antibody
Molecular Weight
17,952 Da
OMIM
600312

Product Categories/Family for anti-NUDT1 antibody

Monoclonal Antibodies; Anti-Human Enzymes

Other Notes

Small volumes of anti-NUDT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NUDT1. It may not necessarily be applicable to this product.

NCBI GI #
133777025
NCBI GeneID
4521
NCBI Accession #
AAH40144.2
UniProt Secondary Accession #
Q6LES7; Q6P0Y6; Q7Z7N6; Q8IV95; Q9UBM0; Q9UBM9; A4D205
UniProt Related Accession #
P36639
NCBI Official Full Name
Nudix (nucleoside diphosphate linked moiety X)-type motif 1
NCBI Official Synonym Full Names
nudix hydrolase 1
NCBI Official Symbol
NUDT1
NCBI Official Synonym Symbols
MTH1
UniProt Protein Name
7,8-dihydro-8-oxoguanine triphosphatase
UniProt Synonym Protein Names
2-hydroxy-dATP diphosphatase (EC:3.6.1.56); 8-oxo-dGTPase; Nucleoside diphosphate-linked moiety X motif 1; Nudix motif 1
Protein Family
7,8-dihydro-8-oxoguanine triphosphatase
UniProt Gene Name
NUDT1
UniProt Synonym Gene Names
MTH1; Nudix motif 1
UniProt Entry Name
8ODP_HUMAN
NCBI Protein Information
7,8-dihydro-8-oxoguanine triphosphatase

UniProt Comments for NUDT1

NUDT1: Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Belongs to the Nudix hydrolase family. 4 isoforms of the human protein are produced by alternative initiation.

Protein type: EC 3.6.1.55; EC 3.6.1.56; Hydrolase

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: cytoplasm; cytosol; mitochondrial matrix; mitochondrion; nucleus

Molecular Function: 8-oxo-7,8-dihydroguanine triphosphatase activity; ATP diphosphatase activity; GTPase activity; m7G(5')pppN diphosphatase activity; protein binding; snoRNA binding

Biological Process: dATP catabolic process; dGTP catabolic process; DNA protection; DNA repair; purine nucleotide catabolic process; response to oxidative stress
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NUDT1 antibody

 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Phosphate Bond Hydrolysis By NUDT Proteins Pathway antibodies  Phosphate Bond Hydrolysis By NUDT Proteins Pathway Diagram
 Oxidized GTP And DGTP Detoxification Pathway antibodies  Oxidized GTP And DGTP Detoxification Pathway Diagram
 Oxidized GTP And DGTP Detoxification Pathway antibodies  Oxidized GTP And DGTP Detoxification Pathway Diagram

Diseases associated with anti-NUDT1 antibody

 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >4 publications with NUDT1 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >2 publications with NUDT1 and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >1 publications with NUDT1 and Cardiovascular Diseases
 Hemorrhage Antibodies  >1 publications with NUDT1 and Hemorrhage
 Heart Diseases Antibodies  >1 publications with NUDT1 and Heart Diseases
 Disease Models, Animal Antibodies  >1 publications with NUDT1 and Disease Models, Animal
 Liver Neoplasms Antibodies  >1 publications with NUDT1 and Liver Neoplasms
 Inflammation Antibodies  >1 publications with NUDT1 and Inflammation
 Necrosis Antibodies  >1 publications with NUDT1 and Necrosis

Organs/Tissues associated with anti-NUDT1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with NUDT1 and Blood
 Lung Antibodies  >5 publications with NUDT1 and Lung
 Brain Antibodies  >3 publications with NUDT1 and Brain
 Heart Antibodies  >2 publications with NUDT1 and Heart
 Liver Antibodies  >2 publications with NUDT1 and Liver
 Placenta Antibodies  >1 publications with NUDT1 and Placenta
 Skin Antibodies  >1 publications with NUDT1 and Skin
 Prostate Antibodies  >1 publications with NUDT1 and Prostate
 Intestine Antibodies  >1 publications with NUDT1 and Intestine
 Muscle Antibodies  >1 publications with NUDT1 and Muscle
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