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Pyruvate Dehydrogenase Complex (PDHX) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140567

Introduction: Pyruvate Dehydrogenase Complex, Component X, also known as PDHX, encodes the E3 binding protein subunit of the PDH complex which contains 3 catalytic subunits. PDHX tethers E3 dimers to the E2 core of the pyruvate dehydrogenase complexes of… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Pyruvate Dehydrogenase Complex (PDHX), Recombinant Protein
Full Product Name
Recombinant Human Pyruvate Dehydrogenase Complex, Component X
Product Gene Name
Product Synonym Names
PDHX Human; Pyruvate Dehydrogenase Complex, Component X Human Recombinant; DLDBP; E3BP; OPDX; PDX1; proX; Pyruvate Dehydrogenase Complex; Component X; Dihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase Complex; Lipoyl-Containing Pyruvate Dehydrogenase Complex Component X; Pyruvate Dehydrogenase Complex; Lipoyl-Containing Component X; Pyruvate Dehydrogenase Complex; E3-Binding Protein Subunit; Pyruvate Dehydrogenase Protein X Component; Mitochondrial; E3-Binding Protein
Sequence
MGSSHHH HHH SSGLVPRGSH MGSGDP IKIL MPSLSPTMEE GNIVKWLKKE GEAVSAGDAL CEIETDKAVV TLDASDDGIL AKIVVEEGSK NIRLGSLIGL IVEEGEDWKH VEIPKDVGPP PPVSKPSEPR PSPEPQISIP VKKEHIPGTL RFRLSPAARN ILEKHSLDAS QGTATGPRGI FTKEDALKLV QLKQTGKITE SRPTPAPTAT PTAPSPLQAT AGPSYPRPVI PPVSTPGQPN AVGTFTEIPA SNIRRVIAKR LTESKSTVPH AYATADCDLG AVLKVRQDLV KDDIKVSVND FIIKAAAVTL KQMPDVNVSW DGEGPKQLPF IDISVAVATD KGLLTPIIKD AAAKGIQEIA DSVKALSKKA RDGKLLPEEY QGGSFSISNL GMFGIDEFTA VINPPQACIL AVGRFRPVLK LTEDEEGNAK LQQRQLITVT MSSDSRVVDD ELATRFLKSF KANLENPIRL A.
Host
E Coli
Form/Format
PDHX protein solution (0.25mg/ml) containing Phosphate buffer saline (pH 7.4) and 20% glycerol, 1mM DTT.
Sterile Filtered clear solution.
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Molecular Weight
51,460 Da
OMIM
245349
3D Structure
ModBase 3D Structure for O00330

Product Categories/Family for PDHX recombinant protein

Other Notes

Small volumes of PDHX recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDHX purchase

MBS140567 is a recombinant protein targeting PDHX. Also known as Recombinant Human Pyruvate Dehydrogenase Complex, Component X. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PDHX. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pyruvate dehydrogenase protein X component, mitochondrial isoform 2
NCBI Official Synonym Full Names
pyruvate dehydrogenase complex component X
NCBI Official Symbol
PDHX
NCBI Official Synonym Symbols
E3BP; OPDX; PDX1; proX; DLDBP
UniProt Protein Name
Pyruvate dehydrogenase protein X component, mitochondrial
UniProt Synonym Protein Names
Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex; E3-binding protein; E3BP; Lipoyl-containing pyruvate dehydrogenase complex component X; proX
UniProt Gene Name
PDHX
UniProt Synonym Gene Names
PDX1; E3BP
UniProt Entry Name
ODPX_HUMAN
NCBI Protein Information
pyruvate dehydrogenase protein X component, mitochondrial

UniProt Comments for PDHX

Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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