• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Interleukin-18 (IL18) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140573

IL 18 Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 158 amino acids (36-192 a.a.) and having a molecular mass of 18.2kDa. The IL 18 is purified by proprietary chromatographic techniques. More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interleukin-18 (IL18), Recombinant Protein
Full Product Name
Recombinant Mouse Interleukin-18
Product Gene Name
IL18 recombinant protein
Product Synonym Gene Name
mIL18
Product Synonym Names
IL 18 Mouse; Interleukin-18 Mouse Recombinant; Interleukin-18; IL-18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma
Sequence
MNFGRLHCTT AVIRNINDQV LFVDKRQPVF EDMTDIDQSA SEPQTRLIIY MYKDSEVRGL AVTLSVKDSK MSTLSCKNKI ISFEEMDPPE NIDDIQSDLI FFQKRVPGHN KMEFESSLYE GHFLACQKED DAFKLILKKK DENGDKSVMF TLTNLHQS
Host
E Coli
Form/Format
The IL 18 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH7.4).
Sterile Filtered clear solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.
Molecular Weight
22,135 Da
3D Structure
ModBase 3D Structure for P70380

Product Categories/Family for IL18 recombinant protein

Cytokines and Growth Factors

Other Notes

Small volumes of IL18 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL18 purchase

MBS140573 is a recombinant protein targeting IL18. Also known as Recombinant Mouse Interleukin-18. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for IL18. It may not necessarily be applicable to this product.

NCBI GI #
6680413
NCBI GeneID
16173
NCBI Accession #
NP_032386.1
UniProt Primary Accession #
P70380
UniProt Related Accession #
P70380
GenBank Nucleotide #
NM_008360.1
NCBI Official Full Name
interleukin-18
NCBI Official Synonym Full Names
interleukin 18
NCBI Official Symbol
Il18
NCBI Official Synonym Symbols
Igif; Il-18
UniProt Protein Name
Interleukin-18
UniProt Synonym Protein Names
Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma
Protein Family
Interleukin
UniProt Gene Name
Il18
UniProt Synonym Gene Names
Igif; IL-18; IFN-gamma-inducing factor; IL-1 gamma
UniProt Entry Name
IL18_MOUSE
NCBI Protein Information
interleukin-18

UniProt Comments for IL18

IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family.

Protein type: Cytokine

Cellular Component: apical plasma membrane; cytoplasm; extracellular space

Molecular Function: cytokine activity

Biological Process: activation of protein kinase B; angiogenesis; cholesterol homeostasis; detection of mechanical stimulus involved in sensory perception of pain; immune response; induction of apoptosis via death domain receptors; inflammatory response; interferon-gamma biosynthetic process; interleukin-13 biosynthetic process; lipopolysaccharide-mediated signaling pathway; MAPKKK cascade; natural killer cell activation; negative regulation of myoblast differentiation; negative regulation of neutrophil apoptosis; negative regulation of peptidyl-tyrosine phosphorylation; positive regulation of activated T cell proliferation; positive regulation of apoptosis; positive regulation of chemokine production; positive regulation of collagen biosynthetic process; positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of interferon-gamma production; positive regulation of interleukin-17 production; positive regulation of interleukin-8 production; positive regulation of natural killer cell proliferation; positive regulation of neuron apoptosis; positive regulation of NF-kappaB import into nucleus; positive regulation of NK T cell proliferation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; positive regulation of superoxide release; positive regulation of T-helper 2 cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of vascular permeability; regulation of cell adhesion; response to hypoxia; sleep; T-helper 1 type immune response
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL18 recombinant protein

 Reference Product  PubMed Publications
 Casp1 recombinant protein  >658 publications with IL18 and Casp1
 Il18r1 recombinant protein  >235 publications with IL18 and Il18r1
 Il1b recombinant protein  >89 publications with IL18 and Il1b
 Il18rap recombinant protein  >44 publications with IL18 and Il18rap
 Cd69 recombinant protein  >28 publications with IL18 and Cd69
 Stat3 recombinant protein  >25 publications with IL18 and Stat3
 Il18bp recombinant protein  >21 publications with IL18 and Il18bp
 Rela recombinant protein  >13 publications with IL18 and Rela
 Nfkb1 recombinant protein  >6 publications with IL18 and Nfkb1

Pathways associated with IL18 recombinant protein

 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Hypertrophy Model Pathway antibodies  Hypertrophy Model Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram

Diseases associated with IL18 recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1395 publications with IL18 and Inflammation
 Necrosis Antibodies  >869 publications with IL18 and Necrosis
 Cardiovascular Diseases Antibodies  >501 publications with IL18 and Cardiovascular Diseases
 Lung Diseases Antibodies  >368 publications with IL18 and Lung Diseases
 Kidney Diseases Antibodies  >366 publications with IL18 and Kidney Diseases
 Hypersensitivity Antibodies  >293 publications with IL18 and Hypersensitivity
 Heart Diseases Antibodies  >242 publications with IL18 and Heart Diseases
 Arthritis, Rheumatoid Antibodies  >234 publications with IL18 and Arthritis, Rheumatoid
 Hypersensitivity, Immediate Antibodies  >207 publications with IL18 and Hypersensitivity, Immediate
 Atherosclerosis Antibodies  >175 publications with IL18 and Atherosclerosis

Organs/Tissues associated with IL18 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >456 publications with IL18 and Liver
 Spleen Antibodies  >297 publications with IL18 and Spleen
 Brain Antibodies  >247 publications with IL18 and Brain
 Skin Antibodies  >239 publications with IL18 and Skin
 Intestine Antibodies  >192 publications with IL18 and Intestine
 Eye Antibodies  >54 publications with IL18 and Eye
 Stomach Antibodies  >43 publications with IL18 and Stomach
 Embryonic Tissue Antibodies  >39 publications with IL18 and Embryonic Tissue
 Thymus Antibodies  >30 publications with IL18 and Thymus
 Ovary Antibodies  >29 publications with IL18 and Ovary
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000