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TIAL1 Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140616

Introduction: TIAL1 belongs to a family of RNA-binding proteins, it has 3 RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a extensive range of genes. TIAL1 regulates a variety of activities including… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TIAL1, Recombinant Protein
Full Product Name
Recombinant Human TIAL1
Product Gene Name
Product Synonym Names
TIAL1 Human; TIAL1 Human Recombinant; TCBP; TIAR; TIA1 cytotoxic granule-associated RNA binding protein-like 1; TIA-1-related protein
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMME DDGQ PRTLYVGNLS RDVTEVLILQ LFSQIGPCKS CKMITEHTSN DPYCFVEFYE HRDAAAALAA MNGRKILGKE VKVNWATTPS SQKKDTSNHF HVFVGDLSPE ITTEDIKSAF APFGKISDAR VVKDMATGKS KGYGFVSFYN KLDAENAIVH MGGQWLGGRQ IRTNWATRKP PAPKSTQENN TKQLRFEDVV NQSSPKNCTV YCGGIASGLT DQLMRQTFSP FGQIMEIRVF PEKGYSFVRF STHESAAHAI VSVNGTTIEG HVVKCYWGKE SPDMTKNFQQ VDYSQWGQWS QVYGNPQQYG QYMANGWQVP PYGVYGQPWN QQGFGVDQSP SAAWMGGFGA QPPQGQAPPP VIPPPNQAGY GMASYQTQ
Form/Format
TIAL1 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 50% glycerol, 2mM DTT and 1mM EDTA
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
OMIM
603413
3D Structure
ModBase 3D Structure for Q01085
Source
E.Coli
Physical Appearance
Sterile Filtered clear solution.

Other Notes

Small volumes of TIAL1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TIAL1 purchase

MBS140616 is a recombinant protein targeting TIAL1. Also known as Recombinant Human TIAL1.

Additional Details

NCBI/Uniprot data below describe general gene information for TIAL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nucleolysin TIAR isoform 2
NCBI Official Synonym Full Names
TIA1 cytotoxic granule-associated RNA binding protein-like 1
NCBI Official Symbol
TIAL1
NCBI Official Synonym Symbols
TCBP; TIAR
UniProt Protein Name
Nucleolysin TIAR
UniProt Synonym Protein Names
TIA-1-related protein
Protein Family
UniProt Gene Name
TIAL1
UniProt Entry Name
TIAR_HUMAN
NCBI Protein Information
nucleolysin TIAR

UniProt Comments for TIAL1

TIAL1: a member of a family of RNA-binding proteins that possesses nucleolytic activity. A cytotoxic T cell granule-associated protein that has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. Members of this protein family may be involved in the induction of apoptosis. Two splice variant isoforms have been described.

Protein type: Apoptosis; RNA-binding

Chromosomal Location of Human Ortholog: 10q

Cellular Component: cytoplasm; lysosome; nucleoplasm; nucleus; stress granule

Molecular Function: RNA binding

Biological Process: defense response; fibroblast growth factor receptor signaling pathway; regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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