Human MX1 Recombinant Protein – Cat# MBS140625

Myxovirus Resistance 1 (MX1) Human Recombinant Protein

Name: MX1 Recombinant Protein; Myxovirus Resistance 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS140625
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140625

Introduction: Myxovirus Resistance 1, also known as MX1 is a guanosine triphosphate (GTP)-metabolizing protein which takes part in the cellular antiviral response. MX1 is induced by type I and type II interferons, and also antagonizes the replication process… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Myxovirus Resistance 1 (MX1), Recombinant Protein

Full Product Name

Recombinant Human Myxovirus Resistance 1

Product Gene Name

MX1 recombinant protein

Product Synonym Names

MX1 Human; Myxovirus Resistance 1 Human Recombinant; MX Dynamin-Like GTPase 1; Interferon-Regulated Resistance GTP-Binding Protein MxA; Interferon-Inducible Protein P78; Interferon-Induced Protein P78; Myxoma Resistance Protein 1; IFI-78K; IFI78; MX; Myxovirus (Influenza) Resistance 1; Homolog Of Murine (Interferon-Inducible Protein P78); Myxovirus (Influenza Virus) Resistance 1; Interferon-Inducible Protein P78 (Mouse); Myxovirus (Influenza Virus) Resistance 1; Interferon-Inducible Protein P78; Interferon-Induced GTP-Binding Protein Mx1; Myxovirus Resistance Protein 1; MxA; Interferon-induced GTP-binding protein Mx1

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMVV SEVD IAKADPAAAS HPLLLNGDAT VAQKNPGSVA ENNLCSQYEE KVRPCIDLID SLRALGVEQD LALPAIAVIG DQSSGKSSVL EALSGVALPR GSGIVTRCPL VLKLKKLVNE DKWRGKVSYQ DYEIEISDAS EVEKEINKAQ NAIAGEGMGI SHELITLEIS SRDVPDLTLI DLPGITRVAV GNQPADIGYK IKTLIKKYIQ RQETISLVVV PSNVDIATTE ALSMAQEVDP EGDRTIGILT KPDLVDKGTE DKVVDVVRNL VFHLKKGYMI VKCRGQQEIQ DQLSLSEALQ REKIFFENHP YFRDLLEEGK ATVPCLAEKL TSELITHICK SLPLLENQIK ETHQRITEEL QKYGVDIPED ENEKMFFLID KVNAFNQDIT ALMQGEETVG EEDIRLFTRL RHEFHKWSTI IENNFQEGHK ILSRKIQKFE NQYRGRELPG FVNYRTFETI VKQQIKALEE PAVDMLHTVT DMVRLAFTDV SIKNFEEFFN LHRTAKSKIE DIRAEQEREG EKLIRLHFQM EQIVYCQDQV YRGALQKVRE KELEEEKKKK SWDFGAFQSS SATDSSMEEI FQHLMAYHQE ASKRISSHIP LIIQFFMLQT YGQQLQKAML QLLQDKDTYS WLLKERSDTS DKRKFLKERL ARLTQARRRL AQFPG

Host

E Coli

Form/Format

MX1 protein solution (0.25mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT.
Sterile Filtered clear solution.

Purity/Purification

Greater than 85% as determined by SDS-PAGE.

Molecular Weight

55,661 Da

OMIM

147150

3D Structure

ModBase 3D Structure for P20591

Product Categories/Family for MX1 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of MX1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MX1 purchase

MBS140625 is a recombinant protein targeting MX1. Also known as Recombinant Human Myxovirus Resistance 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MX1. It may not necessarily be applicable to this product.

NCBI GI #

222136619

NCBI GeneID

4599

NCBI Accession #

NP_001138397.1

UniProt Primary Accession #

P20591

UniProt Secondary Accession #

Q86YP5; Q96CI3; B2RDA5; B3KU10; C9IYV7; C9J8D6; C9JN19; C9JN88; C9JUL1; C9JZS6; D3DSI8

UniProt Related Accession #

P20591

GenBank Nucleotide #

NM_001144925.2

NCBI Official Full Name

interferon-induced GTP-binding protein Mx1 isoform a

NCBI Official Synonym Full Names

MX dynamin like GTPase 1

NCBI Official Symbol

MX1

NCBI Official Synonym Symbols

MX; MxA; IFI78; IFI-78K

UniProt Protein Name

Interferon-induced GTP-binding protein Mx1

UniProt Synonym Protein Names

Interferon-induced protein p78; IFI-78K

Protein Family

Interferon-induced GTP-binding protein

UniProt Gene Name

MX1

UniProt Synonym Gene Names

IFI-78K

UniProt Entry Name

MX1_HUMAN

NCBI Protein Information

interferon-induced GTP-binding protein Mx1

UniProt Comments for MX1

MX1: Dynamin-like GTPase acting as a cell-autonomous host restriction factor against many viral pathogens. Shows activity against influenza viruses, rhabdovirus VSV, bunyavirus LACV, Thogoto virus, measles virus, Hantaan virus, Coxsackie virus CVB, Rift Valley fever virus RVFV, hepatitis B virus HBV, and Crimean- Congo hemorrhagic fever virus CCHFV. Belongs to the dynamin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Hydrolase

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: cytoplasm; cytosol; nuclear membrane; nucleus; perinuclear region of cytoplasm

Molecular Function: GTPase activity; microtubule binding; protein binding

Biological Process: apoptosis; defense response; defense response to virus; innate immune response; negative regulation of viral genome replication; organelle fission; response to virus; signal transduction

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MX1 recombinant protein

Reference Product	PubMed Publications
ISG15 recombinant protein	>78 publications with MX1 and ISG15
OAS1 recombinant protein	>53 publications with MX1 and OAS1
IFIT1 recombinant protein	>32 publications with MX1 and IFIT1
STAT2 recombinant protein	>24 publications with MX1 and STAT2
OAS2 recombinant protein	>17 publications with MX1 and OAS2
OASL recombinant protein	>13 publications with MX1 and OASL
IFIT2 recombinant protein	>11 publications with MX1 and IFIT2
ISG20 recombinant protein	>4 publications with MX1 and ISG20
RNASEL recombinant protein	>3 publications with MX1 and RNASEL
OAS3 recombinant protein	>2 publications with MX1 and OAS3

Pathways associated with MX1 recombinant protein

Products by Pathway	Pathway Diagram
Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies	Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
ISG15 Antiviral Mechanism Pathway antibodies	ISG15 Antiviral Mechanism Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Interferon Signaling Pathway antibodies	Interferon Signaling Pathway Diagram
Interferon Alpha/beta Signaling Pathway antibodies	Interferon Alpha/beta Signaling Pathway Diagram
Measles Pathway antibodies	Measles Pathway Diagram
Measles Pathway antibodies	Measles Pathway Diagram

Diseases associated with MX1 recombinant protein

Disease Name	Pubmed Publications
Influenza, Human Antibodies	>137 publications with MX1 and Influenza, Human
Nervous System Diseases Antibodies	>108 publications with MX1 and Nervous System Diseases
Liver Diseases Antibodies	>97 publications with MX1 and Liver Diseases
Inflammation Antibodies	>59 publications with MX1 and Inflammation
Necrosis Antibodies	>51 publications with MX1 and Necrosis
Fever Antibodies	>38 publications with MX1 and Fever
Cardiovascular Diseases Antibodies	>20 publications with MX1 and Cardiovascular Diseases
Influenza in Birds Antibodies	>19 publications with MX1 and Influenza in Birds
Adenocarcinoma Antibodies	>18 publications with MX1 and Adenocarcinoma
Breast Neoplasms Antibodies	>17 publications with MX1 and Breast Neoplasms

Organs/Tissues associated with MX1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>292 publications with MX1 and Blood
Liver Antibodies	>115 publications with MX1 and Liver
Lung Antibodies	>58 publications with MX1 and Lung
Bone Antibodies	>57 publications with MX1 and Bone
Skin Antibodies	>47 publications with MX1 and Skin
Kidney Antibodies	>44 publications with MX1 and Kidney
Brain Antibodies	>43 publications with MX1 and Brain
Vascular Antibodies	>33 publications with MX1 and Vascular
Spleen Antibodies	>29 publications with MX1 and Spleen
Heart Antibodies	>24 publications with MX1 and Heart