• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

N-Terminal Xaa-Pro-Lys N-Methyltransferase 1 (NTMT1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140638

Introduction: N-terminal Xaa-Pro-Lys N-methyltrasferase1, also known as NTMT1 belongsDescription: NTMT1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 248 amino acids (1-223 a.a) and having a molecular mass of… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
N-Terminal Xaa-Pro-Lys N-Methyltransferase 1 (NTMT1), Recombinant Protein
Full Product Name
Recombinant Human N-Terminal Xaa-Pro-Lys N-Methyltransferase 1
Product Gene Name
NTMT1 recombinant protein
Product Synonym Names
NTMT1 Human; N-Terminal Xaa-Pro-Lys N-Methyltransferase 1 Human Recombinant; NTMT1; N-Terminal Xaa-Pro-Lys N-Methyltransferase 1; X-Pro-Lys N-Terminal Protein Methyltransferase 1A; Alpha N-Terminal Protein Methyltransferase 1A; Methyltransferase-Like Protein 11A; N-Terminal RCC1 Methyltransferase; METTL11A; C9orf32; NTM1A; NRMT; Chromosome 9 Open Reading Frame 32; Methyltransferase Like 11A; EC 2.1.1.244; AD-003; HOMT1A; NRMT1
Sequence
MGSSHHH HHH SSGLVPRGSH MGSEFM TSEV IEDEKQFYSK AKTYWKQIPP TVDGMLGGYG HISSIDINSS RKFLQRFLRE GPNKTGTSCA LDCGAGIGRI TKRLLLPLFR EVDMVDITED FLVQAKTYLG EEGKRVRNYF CCGLQDFTPE PDSYDVIWIQ WVIGHLTDQH LAEFLRRCKG SLRPNGIIVI KDNMAQEGVI LDDVDSSVCR DLDVVRRIIC SAGLSLLAEE RQENLPDEIY HVYSFALR
Host
E Coli
Form/Format
NTMT1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Molecular Weight
15,896 Da
OMIM
613560
3D Structure
ModBase 3D Structure for Q9BV86

Product Categories/Family for NTMT1 recombinant protein

Enzymes

Other Notes

Small volumes of NTMT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NTMT1 purchase

MBS140638 is a recombinant protein targeting NTMT1. Also known as Recombinant Human N-Terminal Xaa-Pro-Lys N-Methyltransferase 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NTMT1. It may not necessarily be applicable to this product.

NCBI GI #
557948057
NCBI GeneID
28989
NCBI Accession #
NP_001273725.1
UniProt Primary Accession #
Q9BV86
UniProt Secondary Accession #
Q5SZB9; Q9UI28; A8K4J2; A8K8G7
UniProt Related Accession #
Q9BV86
GenBank Nucleotide #
NM_001286796.1
NCBI Official Full Name
N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform a
NCBI Official Synonym Full Names
N-terminal Xaa-Pro-Lys N-methyltransferase 1
NCBI Official Symbol
NTMT1
NCBI Official Synonym Symbols
NRMT; NTM1A; AD-003; HOMT1A; C9orf32; METTL11A
UniProt Protein Name
N-terminal Xaa-Pro-Lys N-methyltransferase 1
UniProt Synonym Protein Names
Alpha N-terminal protein methyltransferase 1A; Methyltransferase-like protein 11A; N-terminal RCC1 methyltransferase; X-Pro-Lys N-terminal protein methyltransferase 1A; NTM1A
Protein Family
N-terminal Xaa-Pro-Lys N-methyltransferase
UniProt Gene Name
NTMT1
UniProt Synonym Gene Names
C9orf32; METTL11A; NRMT; NRMT1; NTM1A
UniProt Entry Name
NTM1A_HUMAN
NCBI Protein Information
N-terminal Xaa-Pro-Lys N-methyltransferase 1

UniProt Comments for NTMT1

METTL11A: Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]- Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di- methylation of Pro in the Pro-Pro-Lys motif. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1. Belongs to the methyltransferase superfamily. NTM1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.1.1.244; Methyltransferase; Methyltransferase, protein N-term

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: histone methyltransferase activity; protein methyltransferase activity

Biological Process: chromosome segregation; histone methylation; N-terminal peptidyl-alanine methylation; N-terminal peptidyl-glycine methylation; N-terminal peptidyl-proline di-methylation; spindle organization and biogenesis
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with NTMT1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >1 publications with NTMT1 and Heart
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000