Human ULBP4 Recombinant Protein – Cat# MBS140651

UL16 Binding Protein 4 (ULBP4) Human Recombinant Protein

Name: ULBP4 Recombinant Protein; UL16 Binding Protein 4; Human; MyBioSource
Brand: MyBioSource
SKU: MBS140651
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140651

Introduction: UL16 Binding Protein 4 (ULBP4) is a member of the RAET1 family, which is comprised of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. ULBP4 functions as a ligand for the NKG2D… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

UL16 Binding Protein 4 (ULBP4), Recombinant Protein

Full Product Name

Recombinant Human UL16 Binding Protein 4

Product Gene Name

ULBP4 recombinant protein

Product Synonym Names

ULBP4 Human; UL16 Binding Protein 4 Human Recombinant; Retinoic Acid Early Transcript 1E; Lymphocyte Effector Toxicity Activation Ligand; RAE-1-Like Transcript 4; NKG2DL4; N2DL-4; LETAL; ULBP4; RL-4; NKG2D Ligand 4; BA350J20.7; RAET1E2; N2DL4; RAET1E

Sequence

MKHHHHH HASHSL CFNFTIK SLSRPGQPWC EAQVFLNKNL FLQYNSDNNM VKPLGLLGKK VYATSTWGEL TQTLGEVGRD LRMLLCDIKP QIKTSDPSTL QVEMFCQREA ERCTGASWQF ATNGEKSLLF DAMNMTWTVI NHEASKIKET WKKDRGLEKY FRKLSKGDCD HWLREFLGHW EAMPEPTGRR ST.

Host

E Coli

Form/Format

ULBP4 was filtered (0.4 um) and lyophilized in 0.05M Acetate buffer pH 4.0, 1% (w/v) Sucrose and 4% (w/v) Mannitol.
Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Purity as determined by densitometric image analysis is greater than 85%.

Preparation and Storage

Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.

Molecular Weight

23,978 Da

OMIM

609243

3D Structure

ModBase 3D Structure for Q8TD07

Solubility

It is recommended to add 0.1M acetate buffer pH 4.0 to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10 ug/ml. In higher concentrations the solubility of this antigen is limited. ULBP4 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Product Categories/Family for ULBP4 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of ULBP4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ULBP4 purchase

MBS140651 is a recombinant protein targeting ULBP4. Also known as Recombinant Human UL16 Binding Protein 4. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ULBP4. It may not necessarily be applicable to this product.

NCBI GI #

343183381

NCBI GeneID

135250

NCBI Accession #

NP_001230254.1

UniProt Primary Accession #

Q8TD07

UniProt Secondary Accession #

Q5VYB7; Q5VYB8; Q8TEZ2; Q96L41; A6YF59

UniProt Related Accession #

Q8TD07

GenBank Nucleotide #

NM_001243325.1

NCBI Official Full Name

NKG2D ligand 4 isoform 2

NCBI Official Synonym Full Names

retinoic acid early transcript 1E

NCBI Official Symbol

RAET1E

NCBI Official Synonym Symbols

RL-4; LETAL; ULBP4; N2DL-4; NKG2DL4; RAET1E2; bA350J20.7

UniProt Protein Name

NKG2D ligand 4

UniProt Synonym Protein Names

Lymphocyte effector toxicity activation ligand; RAE-1-like transcript 4; RL-4; Retinoic acid early transcript 1E

UniProt Gene Name

RAET1E

UniProt Synonym Gene Names

LETAL; N2DL4; ULBP4; N2DL-4; NKG2DL4; RL-4

UniProt Entry Name

N2DL4_HUMAN

NCBI Protein Information

NKG2D ligand 4

UniProt Comments for ULBP4

RAET1E: Ligand for the NKG2D receptor. Delivers activating signals to NK cells and promotes tumor immune surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes. Belongs to the MHC class I family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q25.1

Cellular Component: plasma membrane

Molecular Function: antigen binding; natural killer cell lectin-like receptor binding

Biological Process: antigen processing and presentation; natural killer cell mediated cytotoxicity; regulation of immune response; T cell mediated cytotoxicity

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ULBP4 recombinant protein

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies	Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
Natural Killer Cell Mediated Cytotoxicity Pathway antibodies	Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
Natural Killer Cell Mediated Cytotoxicity Pathway antibodies	Natural Killer Cell Mediated Cytotoxicity Pathway Diagram

Diseases associated with ULBP4 recombinant protein

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>3 publications with ULBP4 and Disease Models, Animal
Atherosclerosis Antibodies	>2 publications with ULBP4 and Atherosclerosis
Cardiovascular Diseases Antibodies	>2 publications with ULBP4 and Cardiovascular Diseases
Arteriosclerosis Antibodies	>2 publications with ULBP4 and Arteriosclerosis
Carcinoma, Hepatocellular Antibodies	>1 publications with ULBP4 and Carcinoma, Hepatocellular
Nervous System Diseases Antibodies	>1 publications with ULBP4 and Nervous System Diseases
Liver Diseases Antibodies	>1 publications with ULBP4 and Liver Diseases
Liver Neoplasms Antibodies	>1 publications with ULBP4 and Liver Neoplasms
Necrosis Antibodies	>1 publications with ULBP4 and Necrosis

Organs/Tissues associated with ULBP4 recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>2 publications with ULBP4 and Liver
Brain Antibodies	>1 publications with ULBP4 and Brain
Skin Antibodies	>1 publications with ULBP4 and Skin
Cervix Antibodies	>1 publications with ULBP4 and Cervix