Candida Glabrata UBA4 Recombinant Protein – Cat# MBS1406623

Adenylyltransferase and Sulfurtransferase UBA4 (UBA4) Candida Glabrata Recombinant Protein

Name: UBA4 Recombinant Protein; Candida Glabrata; MyBioSource
Brand: MyBioSource
SKU: MBS1406623
Price: 1195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1406623

MBS1406623 is a recombinant protein targeting UBA4. Also known as Recombinant Candida glabrata Adenylyltransferase and sulfurtransferase UBA4 (UBA4). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1195 / 0.05 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Adenylyltransferase and sulfurtransferase UBA4 (UBA4), Recombinant Protein

Full Product Name

Recombinant Candida glabrata Adenylyltransferase and sulfurtransferase UBA4 (UBA4)

Product Gene Name

UBA4 recombinant protein

Product Synonym Gene Name

UBA4; CAGL0I01254g

Product Synonym Names

Adenylyltransferase and sulfurtransferase UBA4; Ubiquitin-like protein activator 4; Including the following 2 domains:; Adenylyltransferase UBA4; EC=2.7.7.-; Sulfurtransferase UBA4; EC=2.8.1.-

Sequence

MTDQDLLAQI ELLKKENAQL KEKLKSQDDE QLSLEEYSRY GRQMIVEGTG GVVGQLRLKK AKVLVVGAGG LGSPSLPYLV GAGVGTIGIV DNDIVDTSNL HRQTIHNTAK VGMLKCESAK QVLKDLNPHV NINTYPVRLG PENAFSIFAD YDIVMDCTDT PLTRYLISDV AVNLGKTVVS ASGLGTEGQL TILNFNNIGP CYRCFYPVSP NPYAVSSCQE GGVIGPCIGL VGTMMAVETL KIIMGVYNNE NFEPFLLSYS GFPIQSLRRF KMRGRQSKCQ TCGDAPVITK EAIESGIIDY NIFCGSRNYN VCAEGERLTA KEFDENYGPE FSGNNKVLLD VRPSHHFDIS HFNNAVNIPL KELRDMDGDI STLQSRIPNI NKNSEVVVLC RYGNDSQLAT RMLKDEFGIT NVKDVAGGFF KYIDDVDQSI PKY

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

47,669 Da

Sequence Positions

1-433aa; full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q6FR35

Species

Candida glabrata (strain 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of UBA4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UBA4. It may not necessarily be applicable to this product.

NCBI GI #

50289755

NCBI GeneID

2889117

NCBI Accession #

XP_447309.1

UniProt Primary Accession #

Q6FR35

UniProt Related Accession #

Q6FR35

GenBank Nucleotide #

XM_447309.1

NCBI Official Full Name

hypothetical protein

NCBI Official Symbol

CAGL0I01254g

UniProt Protein Name

Adenylyltransferase and sulfurtransferase UBA4

UniProt Synonym Protein Names

Ubiquitin-like protein activator 4; ;

Protein Family

Adenylyltransferase and sulfurtransferase

UniProt Gene Name

UBA4

UniProt Entry Name

UBA4_CANGA

NCBI Protein Information

hypothetical protein

UniProt Comments for UBA4

Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. Prior mcm5 tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with UBA4 recombinant protein

Products by Pathway	Pathway Diagram
Sulfur Relay System Pathway antibodies	Sulfur Relay System Pathway Diagram
Sulfur Relay System Pathway antibodies	Sulfur Relay System Pathway Diagram