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TIR Domain-Containing Adapter Molecule 2 (TICAM2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1406808

MBS1406808 is a recombinant protein targeting Ticam2. Also known as Recombinant Mouse TIR domain-containing adapter molecule 2 (Ticam2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$895 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TIR domain-containing adapter molecule 2 (Ticam2), Recombinant Protein
Full Product Name
Recombinant Mouse TIR domain-containing adapter molecule 2 (Ticam2)
Product Synonym Gene Name
Ticam2
Sequence
GVGKSKLDKC PLSWHKKDSV DADQDGHESD SKNSEEACLR GFVEQSSGSE PPTGEQDQPE AKGAGPEEQD EEEFLKFVIL HAEDDTDEAL RVQDLLQNDF GIRPGIVFAE MPCGRLHLQN LDDAVNGSAW TILLLTENFL RDTWCNFQFY TSLMNSVSRQ HKYNSVIPMR PLNSPLPRER TPLALQTINA LEEESQGFST QVERIFRESV FERQQSIWKE TRSVSQKQFI A
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
26,362 Da
Sequence Positions
2-232, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8BJQ4
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ticam2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ticam2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TIR domain-containing adapter molecule 2
NCBI Official Synonym Full Names
toll-like receptor adaptor molecule 2
NCBI Official Symbol
Ticam2
NCBI Official Synonym Symbols
TRAM; Tirp; Trif; TICAM-2; B430113A10
UniProt Protein Name
TIR domain-containing adapter molecule 2
UniProt Synonym Protein Names
TRIF-related adapter molecule; Toll/interleukin-1 receptor domain-containing protein
UniProt Gene Name
Ticam2
UniProt Synonym Gene Names
Tirp; Tram; TICAM-2
NCBI Protein Information
TIR domain-containing adapter molecule 2

UniProt Comments for Ticam2

Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. May also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial. Involved in IL-18 signaling and is proposed to function as a sorting adaptor for MYD88 in IL-18 signaling during adaptive immune response.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with Ticam2 recombinant protein

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