Human FUCA1 Recombinant Protein – Cat# MBS140720

Fucosidase Alpha-L- 1 Plasma (FUCA1) Human Recombinant Protein

Name: FUCA1 Recombinant Protein; Fucosidase Alpha-L- 1 Plasma; Human; MyBioSource
Brand: MyBioSource
SKU: MBS140720
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140720

Introduction: Fucosidase Alpha-L- 1 Plasma, also known as FUCA1 is a member of the glycosyl hydrolase 29 family which is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of… More details

$250 / 0.001 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fucosidase Alpha-L- 1 Plasma (FUCA1), Recombinant Protein

Full Product Name

Recombinant Human Fucosidase Alpha-L- 1 Plasma

Product Gene Name

FUCA1 recombinant protein

Product Synonym Names

FUCA1 Human; Fucosidase Alpha-L- 1 Plasma Human Recombinant; Fucosidase; Alpha-L- 1; Tissue; Alpha-L-Fucoside Fucohydrolase 1; Alpha-L-Fucosidase 1; Alpha-L-Fucosidase I; EC 3.2.1.51; Tissue Alpha-L-Fucosidase; EC 3.2.1; FUCA; Tissue alpha-L-fucosidase

Sequence

VRRAQPPRRY TPDWPSLDSR PLPAWFDEAK FGVFIHWGVF SVPAWGSEWF WWHWQGEGRP QYQRFMRDNY PPGFSYADFG PQFTARFFHP EEWADLFQAA GAKYVVLTTK HHEGFTNWPS PVSWNWNSKD VGPHRDLVGE LGTALRKRNI RYGLYHSLLE WFHPLYLLDK KNGFKTQHFV SAKTMPELYD LVNSYKPDLI WSDGEWECPD TYWNSTNFLS WLYNDSPVKD EVVVNDRWGQ NCSCHHGGYY NCEDKFKPQS LPDHKWEMCT SIDKFSWGYR RDMALSDVTE ESEIISELVQ TVSLGGNYLL NIGPTKDGLI VPIFQERLLA VGKWLSINGE AIYASKPWRV QWEKNTTSVW YTSKGSAVYA IFLHWPENGV LNLESPITTS TTKITMLGIQ GDLKWSTDPD KGLFISLPQL PPSAVPAEFA WTIKLTGVK< u>H HHHHH

Host

Sf9 Baculovirus Cells

Form/Format

FUCA1 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90% as determined by SDS-PAGE.

Molecular Weight

53,689 Da

OMIM

230000

3D Structure

ModBase 3D Structure for P04066

Product Categories/Family for FUCA1 recombinant protein

Enzymes

Other Notes

Small volumes of FUCA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FUCA1 purchase

MBS140720 is a recombinant protein targeting FUCA1. Also known as Recombinant Human Fucosidase Alpha-L- 1 Plasma. Host: Sf9 Baculovirus Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for FUCA1. It may not necessarily be applicable to this product.

NCBI GI #

119360348

NCBI GeneID

2517

NCBI Accession #

NP_000138.2

UniProt Primary Accession #

P04066

UniProt Secondary Accession #

Q14334; Q14335; Q3LID0; Q8NAC2; B2RBG3

UniProt Related Accession #

P04066

GenBank Nucleotide #

NM_000147.4

NCBI Official Full Name

tissue alpha-L-fucosidase

NCBI Official Synonym Full Names

fucosidase, alpha-L- 1, tissue

NCBI Official Symbol

FUCA1

NCBI Official Synonym Symbols

FUCA

UniProt Protein Name

Tissue alpha-L-fucosidase

UniProt Synonym Protein Names

Alpha-L-fucosidase I; Alpha-L-fucoside fucohydrolase 1; Alpha-L-fucosidase 1

Protein Family

Tissue alpha-L-fucosidase

UniProt Gene Name

FUCA1

UniProt Synonym Gene Names

Alpha-L-fucosidase 1

UniProt Entry Name

FUCO_HUMAN

NCBI Protein Information

tissue alpha-L-fucosidase

UniProt Comments for FUCA1

FUCA1: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins. Defects in FUCA1 are the cause of fucosidosis (FUCA1D). FUCA1D is an autosomal recessive lysosomal storage disease characterized by accumulation of fucose-containing glycolipids and glycoproteins in various tissues. Clinical signs include facial dysmorphism, dysostosis multiplex, moderate hepatomegaly, severe intellectual deficit, deafness, and according to age, angiokeratomas. Belongs to the glycosyl hydrolase 29 family.

Protein type: EC 3.2.1.51; Glycan Metabolism - other glycan degradation; Hydrolase

Chromosomal Location of Human Ortholog: 1p34

Cellular Component: cytoplasm; lysosomal lumen

Molecular Function: alpha-L-fucosidase activity

Biological Process: fucose metabolic process; glycoside catabolic process

Disease: Fucosidosis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FUCA1 recombinant protein

Products by Pathway	Pathway Diagram
Asparagine N-linked Glycosylation Pathway antibodies	Asparagine N-linked Glycosylation Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway antibodies	N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway Diagram
Other Glycan Degradation Pathway antibodies	Other Glycan Degradation Pathway Diagram
Other Glycan Degradation Pathway antibodies	Other Glycan Degradation Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram
Reactions Specific To The Complex N-glycan Synthesis Pathway antibodies	Reactions Specific To The Complex N-glycan Synthesis Pathway Diagram
Transport To The Golgi And Subsequent Modification Pathway antibodies	Transport To The Golgi And Subsequent Modification Pathway Diagram

Diseases associated with FUCA1 recombinant protein

Disease Name	Pubmed Publications
Fucosidosis Antibodies	>8 publications with FUCA1 and Fucosidosis
Carcinoma Antibodies	>5 publications with FUCA1 and Carcinoma
Adenocarcinoma Antibodies	>3 publications with FUCA1 and Adenocarcinoma
Neoplasm Metastasis Antibodies	>3 publications with FUCA1 and Neoplasm Metastasis
Liver Diseases Antibodies	>2 publications with FUCA1 and Liver Diseases
Liver Neoplasms Antibodies	>2 publications with FUCA1 and Liver Neoplasms
Disease Models, Animal Antibodies	>1 publications with FUCA1 and Disease Models, Animal
Cardiovascular Diseases Antibodies	>1 publications with FUCA1 and Cardiovascular Diseases
Hypertrophy Antibodies	>1 publications with FUCA1 and Hypertrophy
Breast Neoplasms Antibodies	>1 publications with FUCA1 and Breast Neoplasms

Organs/Tissues associated with FUCA1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>17 publications with FUCA1 and Blood
Liver Antibodies	>3 publications with FUCA1 and Liver
Intestine Antibodies	>3 publications with FUCA1 and Intestine
Lung Antibodies	>2 publications with FUCA1 and Lung
Lymph Antibodies	>2 publications with FUCA1 and Lymph
Lymph Node Antibodies	>2 publications with FUCA1 and Lymph Node
Brain Antibodies	>2 publications with FUCA1 and Brain
Skin Antibodies	>1 publications with FUCA1 and Skin
Bone Antibodies	>1 publications with FUCA1 and Bone
Stomach Antibodies	>1 publications with FUCA1 and Stomach