Human B9D1 Recombinant Protein – Cat# MBS140722

B9 Protein Domain 1 (B9D1) Human Recombinant Protein

Name: B9D1 Recombinant Protein; B9 Protein Domain 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS140722
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140722

Introduction: B9 domain-containing protein (B9D1) is one of the numerous proteins which take part in ciliogenesis. Alterations in expression of B9D1 have been found in a family with Meckel syndrome. The Meckel syndrome has been associated with at least six… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

B9 Protein Domain 1 (B9D1), Recombinant Protein

Full Product Name

Recombinant Human B9 Protein Domain 1

Product Gene Name

B9D1 recombinant protein

Product Synonym Names

B9D1 Human; B9 Protein Domain 1 Human Recombinant; B9 Protein Domain 1; MKSR1; Endothelial Precursor Protein B9; MKS1-Related Protein 1; MKS9; B9 Domain-Containing Protein 1; EPPB9; B9; B9 domain-containing protein 1

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMAT ASPS VFLLMVNGQV ESAQFPEYDD LYCKYCFVYG QDWAPTAGLE EGISQITSKS QDVRQALVWN FPIDVTFKST NPYGWPQIVL SVYGPDVFGN DVVRGYGAVH VPFSPGRHKR TIPMFVPEST SKLQKFTSWF MGRRPEYTDP KVVAQGEGRE VTRVRSQGFV TLLFNVVTKD MRKLGYDTGP SDTQGVLGPS PPQSFPQ

Host

E Coli

Form/Format

B9D1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 85% as determined by SDS-PAGE.

Molecular Weight

16,919 Da

OMIM

614144

3D Structure

ModBase 3D Structure for Q9UPM9

Product Categories/Family for B9D1 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of B9D1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for B9D1 purchase

MBS140722 is a recombinant protein targeting B9D1. Also known as Recombinant Human B9 Protein Domain 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for B9D1. It may not necessarily be applicable to this product.

NCBI GI #

7661536

NCBI GeneID

27077

NCBI Accession #

NP_056496.1

UniProt Primary Accession #

Q9UPM9

UniProt Secondary Accession #

Q9BU22

UniProt Related Accession #

Q9UPM9

GenBank Nucleotide #

NM_015681.4

NCBI Official Full Name

B9 domain-containing protein 1 isoform b

NCBI Official Synonym Full Names

B9 protein domain 1

NCBI Official Symbol

B9D1

NCBI Official Synonym Symbols

B9; MKS9; EPPB9; MKSR1

UniProt Protein Name

B9 domain-containing protein 1

UniProt Synonym Protein Names

MKS1-related protein 1

Protein Family

B9 domain-containing protein

UniProt Gene Name

B9D1

UniProt Synonym Gene Names

MKSR1

UniProt Entry Name

B9D1_HUMAN

NCBI Protein Information

B9 domain-containing protein 1

UniProt Comments for B9D1

B9D1: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling. Defects in B9D1 are the cause of Meckel syndrome type 9 (MKS9). A disorder characterized by a combination of renal cysts and variably associated features including developmental anomalies of the central nervous system (typically encephalocele), hepatic ductal dysplasia and cysts, and polydactyly. Belongs to the B9D family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: centrosome; cytosol

Molecular Function: hedgehog receptor activity

Biological Process: smoothened signaling pathway

Disease: Joubert Syndrome 27; Meckel Syndrome, Type 9

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with B9D1 recombinant protein

Products by Pathway	Pathway Diagram
Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies	Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
Assembly Of The Primary Cilium Pathway antibodies	Assembly Of The Primary Cilium Pathway Diagram
Organelle Biogenesis And Maintenance Pathway antibodies	Organelle Biogenesis And Maintenance Pathway Diagram

Diseases associated with B9D1 recombinant protein

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>7 publications with B9D1 and Kidney Diseases
Nervous System Diseases Antibodies	>6 publications with B9D1 and Nervous System Diseases
Liver Diseases Antibodies	>3 publications with B9D1 and Liver Diseases
Cardiovascular Diseases Antibodies	>2 publications with B9D1 and Cardiovascular Diseases
Hypertension Antibodies	>1 publications with B9D1 and Hypertension
Fibrosis Antibodies	>1 publications with B9D1 and Fibrosis

Organs/Tissues associated with B9D1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>7 publications with B9D1 and Kidney
Liver Antibodies	>3 publications with B9D1 and Liver
Brain Antibodies	>3 publications with B9D1 and Brain
Eye Antibodies	>3 publications with B9D1 and Eye
Embryonic Tissue Antibodies	>1 publications with B9D1 and Embryonic Tissue