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Platelet Endothelial Cell Adhesion Molecule 1 (PECAM1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140757

Introduction: Platelet endothelial cell adhesion molecule (PECAM1) induces susceptibility to atherosclerosis. PECAM1 averts phagocyte ingestion of closely apposed viable cells by transmitting detachment signals, and transforms function upon apoptosis, thus… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Platelet Endothelial Cell Adhesion Molecule 1 (PECAM1), Recombinant Protein
Full Product Name
Recombinant Human Platelet Endothelial Cell Adhesion Molecule 1
Product Gene Name
PECAM1 recombinant protein
Product Synonym Names
PECAM1 Human; Platelet Endothelial Cell Adhesion Molecule 1 Human Recombinant; Platelet endothelial cell adhesion molecule; PECAM1; CD31; CD31/EndoCAM; endoCAM; GPIIA'; PECA1; PECAM-1; Platelet Endothelial Cell Adhesion Molecule 1
Sequence
QENSFTINSV DMKSLPDWTV QNGKNLTLQC FADVSTTSHV KPQHQMLFYK DDVLFYNISS MKSTESYFIP EVRIYDSGTY KCTVIVNNKE KTTAEYQVLV EGVPSPRVTL DKKEAIQGGI VRVNCSVPEE KAPIHFTIEK LELNEKMVKL KREKNSRDQN FVILEFPVEE QDRVLSFRCQ ARIISGIHMQ TSESTKSELV TVTESFSTPK FHISPTGMIM EGAQLHIKCT IQVTHLAQEF PEIIIQKDKA IVAHNRHGNK AVYSVMAMVE HSGNYTCKVE SSRISKVSSI VVNITELFSK PELESSFTHL DQGERLNLSC SIPGAPPANF TIQKEDTIVS QTQDFTKIAS KSDSGTYICT AGIDKVVKKS NTVQIVVCEM LSQPRISYDA QFEVIKGQTI EVRCESISGT LPISYQLLKT SKVLENSTKN SNDPAVFKDN PTEDVEYQCV ADNCHSHAKM LSEVLRVKVI APVDEVQISI LSSKVVESGE DIVLQCAVNE GSGPITYKFY REKEGKPFYQ MTSNATQAFW TKQKASKEQE GEYYCTAFNR ANHASSVPRS KILTVRVILA PWKKVEH HHH HH.
Host
Sf9 Baculovirus Cells
Form/Format
PECAM1 protein solution (0.25mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Sterile filtered colorless solution.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Molecular Weight
81,378 Da
OMIM
173445
3D Structure
ModBase 3D Structure for P16284

Product Categories/Family for PECAM1 recombinant protein

Cytokines and Growth Factors

Other Notes

Small volumes of PECAM1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PECAM1 purchase

MBS140757 is a recombinant protein targeting PECAM1. Also known as Recombinant Human Platelet Endothelial Cell Adhesion Molecule 1. Host: Sf9 Baculovirus Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for PECAM1. It may not necessarily be applicable to this product.

NCBI GI #
313760624
NCBI GeneID
5175
NCBI Accession #
NP_000433.4
UniProt Primary Accession #
P16284
UniProt Secondary Accession #
Q6LDA9; Q8TBH1; Q96RF5; Q96RF6; Q9NP65; Q9NPB7; Q9NPG9; Q9NQS9; Q9NQT0; A8K3S7; D3DU31
UniProt Related Accession #
P16284
GenBank Nucleotide #
NM_000442.4
NCBI Official Full Name
platelet endothelial cell adhesion molecule
NCBI Official Synonym Full Names
platelet and endothelial cell adhesion molecule 1
NCBI Official Symbol
PECAM1
NCBI Official Synonym Symbols
CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM
UniProt Protein Name
Platelet endothelial cell adhesion molecule
UniProt Synonym Protein Names
EndoCAM; GPIIA'; PECA1; CD_antigen: CD31
Protein Family
Platelet endothelial cell adhesion molecule
UniProt Gene Name
PECAM1
UniProt Synonym Gene Names
PECAM-1
UniProt Entry Name
PECA1_HUMAN
NCBI Protein Information
platelet endothelial cell adhesion molecule

UniProt Comments for PECAM1

PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Protein type: Cell adhesion; Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q23.3

Cellular Component: extracellular space; plasma membrane; platelet alpha granule membrane

Molecular Function: protein binding

Biological Process: cell recognition; diapedesis; extracellular matrix organization and biogenesis; leukocyte migration; phagocytosis; platelet degranulation; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PECAM1 recombinant protein

 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram

Diseases associated with PECAM1 recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >565 publications with PECAM1 and Inflammation
 Necrosis Antibodies  >431 publications with PECAM1 and Necrosis
 Neoplasms, Experimental Antibodies  >274 publications with PECAM1 and Neoplasms, Experimental
 Neoplasm Metastasis Antibodies  >267 publications with PECAM1 and Neoplasm Metastasis
 Heart Diseases Antibodies  >261 publications with PECAM1 and Heart Diseases
 Lung Diseases Antibodies  >260 publications with PECAM1 and Lung Diseases
 Breast Neoplasms Antibodies  >216 publications with PECAM1 and Breast Neoplasms
 Liver Diseases Antibodies  >204 publications with PECAM1 and Liver Diseases
 Lung Neoplasms Antibodies  >197 publications with PECAM1 and Lung Neoplasms
 Liver Neoplasms Antibodies  >171 publications with PECAM1 and Liver Neoplasms

Organs/Tissues associated with PECAM1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >3694 publications with PECAM1 and Vascular
 Blood Antibodies  >3252 publications with PECAM1 and Blood
 Muscle Antibodies  >755 publications with PECAM1 and Muscle
 Embryonic Tissue Antibodies  >537 publications with PECAM1 and Embryonic Tissue
 Lung Antibodies  >467 publications with PECAM1 and Lung
 Heart Antibodies  >399 publications with PECAM1 and Heart
 Skin Antibodies  >379 publications with PECAM1 and Skin
 Brain Antibodies  >353 publications with PECAM1 and Brain
 Connective Tissue Antibodies  >280 publications with PECAM1 and Connective Tissue
 Kidney Antibodies  >250 publications with PECAM1 and Kidney
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