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Bone Morphogenetic Protein Receptor-1b (BMPR1B) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140763

Introduction: Bone Morphogenetic protein Receptor-1B, also known as BMPR1B belongs toDescription: BMPR1B Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 136 amino acids (14-126 a.a) and having a molecular mass… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Bone Morphogenetic protein Receptor-1B (BMPR1B), Recombinant Protein
Full Product Name
Recombinant Human Bone Morphogenetic protein Receptor-1B
Product Gene Name
BMPR1B recombinant protein
Product Synonym Names
BMPR1B Human; Bone Morphogenetic protein Receptor-1B Human Recombinant; Bone Morphogenetic Protein Receptor; Type IB; BMP Type-1B Receptor; EC 2.7.11.30; BMPR-1B; ALK6; Bone Morphogenetic Protein Receptor Type-1B; Serine/Threonine Receptor Kinase; Activin Receptor-Like Kinase 6; CDw293 Antigen; EC 2.7.11; CDw293; ALK-6; Bone morphogenetic protein receptor type-1B
Sequence
MGSSHHH HHH SSGLVPRGSH MGSKKE DGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED DSGLPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD GPIHHR
Host
E Coli
Form/Format
BMPR1B protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 20% glycerol, 1mM DTT and 0.1mM PMSF.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 80.0% as determined by SDS-PAGE.
Molecular Weight
60,582 Da
OMIM
112600
3D Structure
ModBase 3D Structure for O00238

Product Categories/Family for BMPR1B recombinant protein

Cytokines and Growth Factors

Other Notes

Small volumes of BMPR1B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMPR1B purchase

MBS140763 is a recombinant protein targeting BMPR1B. Also known as Recombinant Human Bone Morphogenetic protein Receptor-1B. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for BMPR1B. It may not necessarily be applicable to this product.

NCBI GI #
4502431
NCBI GeneID
658
NCBI Accession #
NP_001194.1
UniProt Primary Accession #
O00238
UniProt Secondary Accession #
P78366; B2R953; B4DSV1
UniProt Related Accession #
O00238
GenBank Nucleotide #
NM_001203.2
NCBI Official Full Name
bone morphogenetic protein receptor type-1B isoform b
NCBI Official Synonym Full Names
bone morphogenetic protein receptor type 1B
NCBI Official Symbol
BMPR1B
NCBI Official Synonym Symbols
ALK6; AMDD; BDA2; ALK-6; BDA1D; CDw293
UniProt Protein Name
Bone morphogenetic protein receptor type-1B
UniProt Synonym Protein Names
CD_antigen: CDw293
Protein Family
Bone morphogenetic protein receptor
UniProt Gene Name
BMPR1B
UniProt Synonym Gene Names
BMP type-1B receptor; BMPR-1B
UniProt Entry Name
BMR1B_HUMAN
NCBI Protein Information
bone morphogenetic protein receptor type-1B

UniProt Comments for BMPR1B

BMPR1B: a kinase of the STKR family. A type I cell-surface receptor for bone morphogenetic protein. Expressed at ighest level in the prostate. May be upregulated by androgen stimulation in cells which expresses the androgen receptor.

Protein type: EC 2.7.11.30; Kinase, protein; Membrane protein, integral; Protein kinase, Ser/Thr (receptor); Protein kinase, TKL; STKR family; TKL group; Type1 subfamily

Chromosomal Location of Human Ortholog: 4q22-q24

Cellular Component: integral to plasma membrane; plasma membrane; receptor complex

Molecular Function: ATP binding; glycoprotein binding; protein binding; protein serine/threonine kinase activity; SMAD binding; transmembrane receptor protein serine/threonine kinase activity

Biological Process: BMP signaling pathway; chondrocyte development; eye development; limb morphogenesis; ovarian cumulus expansion; ovulation cycle; positive regulation of bone mineralization; positive regulation of cell differentiation; positive regulation of chondrocyte differentiation; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; proteoglycan biosynthetic process; skeletal development

Disease: Brachydactyly, Type A1, D; Brachydactyly, Type A2; Chondrodysplasia, Acromesomelic, With Genital Anomalies
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with BMPR1B recombinant protein

 Reference Product  PubMed Publications
 BMPR2 recombinant protein  >113 publications with BMPR1B and BMPR2
 BMP2 recombinant protein  >71 publications with BMPR1B and BMP2
 SMAD1 recombinant protein  >51 publications with BMPR1B and SMAD1
 BMP4 recombinant protein  >49 publications with BMPR1B and BMP4
 BMP7 recombinant protein  >33 publications with BMPR1B and BMP7
 GDF5 recombinant protein  >25 publications with BMPR1B and GDF5
 SMAD5 recombinant protein  >22 publications with BMPR1B and SMAD5
 BMP6 recombinant protein  >21 publications with BMPR1B and BMP6
 SMAD9 recombinant protein  >8 publications with BMPR1B and SMAD9
 SMAD6 recombinant protein  >6 publications with BMPR1B and SMAD6

Pathways associated with BMPR1B recombinant protein

 Products by Pathway  Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signalling And Regulation Pathway antibodies  BMP Signalling And Regulation Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Ovarian Infertility Genes Pathway antibodies  Ovarian Infertility Genes Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By BMP Pathway antibodies  Signaling By BMP Pathway Diagram

Diseases associated with BMPR1B recombinant protein

 Disease Name  Pubmed Publications
 Bone Diseases, Developmental Antibodies  >11 publications with BMPR1B and Bone Diseases, Developmental
 Brachydactyly type A2 Antibodies  >9 publications with BMPR1B and Brachydactyly type A2
 Breast Neoplasms Antibodies  >9 publications with BMPR1B and Breast Neoplasms
 Lung Diseases Antibodies  >8 publications with BMPR1B and Lung Diseases
 Disease Models, Animal Antibodies  >7 publications with BMPR1B and Disease Models, Animal
 Craniofacial Abnormalities Antibodies  >5 publications with BMPR1B and Craniofacial Abnormalities
 Ovarian Diseases Antibodies  >5 publications with BMPR1B and Ovarian Diseases
 Prostatic Diseases Antibodies  >5 publications with BMPR1B and Prostatic Diseases
 Inflammation Antibodies  >5 publications with BMPR1B and Inflammation
 Prostatic Neoplasms Antibodies  >5 publications with BMPR1B and Prostatic Neoplasms

Organs/Tissues associated with BMPR1B recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >238 publications with BMPR1B and Bone
 Ovary Antibodies  >35 publications with BMPR1B and Ovary
 Brain Antibodies  >19 publications with BMPR1B and Brain
 Embryonic Tissue Antibodies  >18 publications with BMPR1B and Embryonic Tissue
 Muscle Antibodies  >15 publications with BMPR1B and Muscle
 Connective Tissue Antibodies  >13 publications with BMPR1B and Connective Tissue
 Nerve Antibodies  >12 publications with BMPR1B and Nerve
 Eye Antibodies  >10 publications with BMPR1B and Eye
 Vascular Antibodies  >10 publications with BMPR1B and Vascular
 Lung Antibodies  >10 publications with BMPR1B and Lung
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