Human PTX3 Recombinant Protein – Cat# MBS140769

Pentraxin-3 (PTX3) Human Recombinant Protein

Name: PTX3 Recombinant Protein; Pentraxin-3; Human; MyBioSource
Brand: MyBioSource
SKU: MBS140769
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140769

Introduction: PTX3 is part of the pentraxin family sharing the C-terminal domain with short pentraxins and containing a unique N-terminal domain. PTX3 is produced and released at inflammatory sites by various cell types including monocytes/macrophages,… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Pentraxin-3 (PTX3), Recombinant Protein

Full Product Name

Recombinant Human Pentraxin-3, HEK

Product Gene Name

PTX3 recombinant protein

Product Synonym Names

PTX3 Human, HEK; Pentraxin-3 Human Recombinant, HEK; TSG-14; TNFAIP5; PTX3; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3; Tumor necrosis factor-inducible gene 14 protein; TSG14; pentraxin-related gene rapidly induced by IL-1 beta

Sequence

ENSDDYDLMY VNLDNEIDNG LHPTEDPTPC DCGQEHSEWD KLFIMLENSQ MRERMLLQAT DDVLRGELQR LREELGRLAE SLARPCAPGA PAEARLTSAL DELLQATRDA GRRLARMEGA EAQRPEEAGR ALAAVLEELR QTRADLHAVQ GWAARSWLPA GCETAILFPM RSKKIFGSVH PVRPMRLESF SACIWVKATD VLNKTILFSY GTKRNPYEIQ LYLSYQSIVF VVGGEENKLV AEAMVSLGRW THLCGTWNSE EGLTSLWVNG ELAATTVEMA TGHIVPEGGI LQIGQEKNGC CVGGGFDETL AFSGRLTGFN IWDSVLSNEE IRETGGAESC HIRGNIVGWG VTEIQPHGGA QYVSHHH HHH.

Host

HEK 293

Form/Format

PTX3 was filtered (0.4 um) and lyophilized from 0.5mg/ml solution in phosphate buffered saline.
Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Purity as determined by densitometric image analysis is greater than 95%.

Preparation and Storage

Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.

Molecular Weight

41,976 Da

OMIM

602492

3D Structure

ModBase 3D Structure for P26022

Solubility

It is recommended to add 200 ul deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. PTX3 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Product Categories/Family for PTX3 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of PTX3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTX3 purchase

MBS140769 is a recombinant protein targeting PTX3. Also known as Recombinant Human Pentraxin-3, HEK. Host: HEK 293.

Additional Details

NCBI/Uniprot data below describe general gene information for PTX3. It may not necessarily be applicable to this product.

NCBI GI #

167900484

NCBI GeneID

5806

NCBI Accession #

NP_002843.2

UniProt Primary Accession #

P26022

UniProt Secondary Accession #

Q38M82; B2R6T6

UniProt Related Accession #

P26022

GenBank Nucleotide #

NM_002852.3

NCBI Official Full Name

pentraxin-related protein PTX3

NCBI Official Synonym Full Names

pentraxin 3

NCBI Official Symbol

PTX3

NCBI Official Synonym Symbols

TSG-14; TNFAIP5

UniProt Protein Name

Pentraxin-related protein PTX3

UniProt Synonym Protein Names

Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14

Protein Family

Pentraxin-related protein

UniProt Gene Name

PTX3

UniProt Synonym Gene Names

TNFAIP5; TSG14; TNF alpha-induced protein 5; TSG-14

UniProt Entry Name

PTX3_HUMAN

NCBI Protein Information

pentraxin-related protein PTX3

UniProt Comments for PTX3

PTX3: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q25

Cellular Component: extracellular region; extracellular space

Molecular Function: complement component C1q binding; identical protein binding; protein binding; virion binding

Biological Process: inflammatory response; innate immune response; negative regulation of virion penetration into host cell

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PTX3 recombinant protein

Reference Product	PubMed Publications
TNFAIP6 recombinant protein	>30 publications with PTX3 and TNFAIP6
MYD88 recombinant protein	>6 publications with PTX3 and MYD88
CFH recombinant protein	>2 publications with PTX3 and CFH
C1QA recombinant protein	>1 publications with PTX3 and C1QA

Diseases associated with PTX3 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>421 publications with PTX3 and Inflammation
Cardiovascular Diseases Antibodies	>231 publications with PTX3 and Cardiovascular Diseases
Necrosis Antibodies	>114 publications with PTX3 and Necrosis
Heart Diseases Antibodies	>97 publications with PTX3 and Heart Diseases
Atherosclerosis Antibodies	>95 publications with PTX3 and Atherosclerosis
Nervous System Diseases Antibodies	>66 publications with PTX3 and Nervous System Diseases
Kidney Diseases Antibodies	>59 publications with PTX3 and Kidney Diseases
Lung Diseases Antibodies	>56 publications with PTX3 and Lung Diseases
Myocardial Infarction Antibodies	>47 publications with PTX3 and Myocardial Infarction
Skin Diseases Antibodies	>39 publications with PTX3 and Skin Diseases

Organs/Tissues associated with PTX3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>191 publications with PTX3 and Vascular
Heart Antibodies	>96 publications with PTX3 and Heart
Kidney Antibodies	>74 publications with PTX3 and Kidney
Brain Antibodies	>66 publications with PTX3 and Brain
Lung Antibodies	>65 publications with PTX3 and Lung
Liver Antibodies	>49 publications with PTX3 and Liver
Muscle Antibodies	>39 publications with PTX3 and Muscle
Bone Antibodies	>35 publications with PTX3 and Bone
Connective Tissue Antibodies	>24 publications with PTX3 and Connective Tissue
Embryonic Tissue Antibodies	>22 publications with PTX3 and Embryonic Tissue