Mouse SERPINF2 Recombinant Protein – Cat# MBS140794

Serpin Peptidase Inhibitor (SERPINF2) Mouse Recombinant Protein

Name: SERPINF2 Recombinant Protein; Serpin Peptidase Inhibitor; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS140794
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140794

Introduction: Alpha-2-antiplasmin (SERPINF2) is a serine protease inhibitor. The main targets of SERPINF2 are plasmin and trypsin; however SERPINF2 also inactivates matriptase-3/TMPRSS7 and chymotrypsin.Description: SERPINF2 produced in Sf9 Baculovirus cells… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Serpin Peptidase Inhibitor (SERPINF2), Recombinant Protein

Full Product Name

Recombinant Mouse Serpin Peptidase Inhibitor, Clade F Member 2

Product Gene Name

SERPINF2 recombinant protein

Product Synonym Gene Name

mSERPINF2

Product Synonym Names

SERPINF2 Mouse; Serpin Peptidase Inhibitor, Clade F Member 2 Mouse Recombinant; Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-plasmin inhibitor; Alpha-2-PI; Serpin F2

Sequence

VDLPGQQPVS EQAQQKLPLP ALFKLDNQDF GDHATLKRSP GHCKSVPTAE ETRRLAQAMM AFTTDLFSLV AQTSTSSNLV LSPLSVALAL SHLALGAQNQ TLHSLHRVLH MNTGSCLPHL LSHFYQNLGP GTIRLAARIY LQKGFPIKDD FLEQSERLFG AKPVKLTGKQ EEDLANINQW VKEATEGKIE DFLSELPDST VLLLLNAIHF HGFWRTKFDP SLTQKDFFHL DERFTVSVDM MHAVSYPLRW FLLEQPEIQV AHFPFKNNMS FVVVMPTYFE WNVSEVLANL TWDTLYHPSL QERPTKVWLP KLHLQQQLDL VATLSQLGLQ ELFQGPDLRG ISEQNLVVSS VQHQSTMELS EAGVEAAAAT SVAMNRMSLS SFTVNRPFLF FIMEDTIGVP LFVGSVRNPN PSALPQLQEQ RDSPDNRLIG QNDKADFHGG KTFGPDLKLA PRMEEDYPQF SSPKHHH HHH.

Host

Sf9 Baculovirus Cells

Form/Format

SERPINF2 protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Molecular Weight

54,972 Da

3D Structure

ModBase 3D Structure for Q61247

Product Categories/Family for SERPINF2 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of SERPINF2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SERPINF2 purchase

MBS140794 is a recombinant protein targeting SERPINF2. Also known as Recombinant Mouse Serpin Peptidase Inhibitor, Clade F Member 2. Host: Sf9 Baculovirus Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for SERPINF2. It may not necessarily be applicable to this product.

NCBI GI #

6679383

NCBI GeneID

18816

NCBI Accession #

NP_032904.1

UniProt Primary Accession #

Q61247

UniProt Related Accession #

Q61247

GenBank Nucleotide #

NM_008878.2

NCBI Official Full Name

alpha-2-antiplasmin

NCBI Official Synonym Full Names

serine (or cysteine) peptidase inhibitor, clade F, member 2

NCBI Official Symbol

Serpinf2

NCBI Official Synonym Symbols

Pli; AI747498; Serpimf2

UniProt Protein Name

Alpha-2-antiplasmin

UniProt Synonym Protein Names

Alpha-2-plasmin inhibitor; Alpha-2-PI; Serpin F2

Protein Family

Alpha-2-antiplasmin

UniProt Gene Name

Serpinf2

UniProt Synonym Gene Names

Pli; Alpha-2-AP; Alpha-2-PI

UniProt Entry Name

A2AP_MOUSE

NCBI Protein Information

alpha-2-antiplasmin

UniProt Comments for SERPINF2

SERPINF2: Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. Defects in SERPINF2 are the cause of alpha-2-plasmin inhibitor deficiency (APLID). APLID is an autosomal recessive disorder resulting in severe hemorrhagic diathesis. Belongs to the serpin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: cell surface; extracellular space; fibrinogen complex

Molecular Function: protease binding; protein homodimerization activity; serine-type endopeptidase inhibitor activity

Biological Process: blood vessel morphogenesis; collagen fibril organization; negative regulation of fibrinolysis; positive regulation of cell differentiation; positive regulation of collagen biosynthetic process; positive regulation of JNK cascade; positive regulation of smooth muscle cell proliferation; positive regulation of stress fiber formation; positive regulation of transcription from RNA polymerase II promoter; renin-angiotensin regulation of blood vessel size

Disease: Alpha-2-plasmin Inhibitor Deficiency

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SERPINF2 recombinant protein

Products by Pathway	Pathway Diagram
Blood Clotting Cascade Pathway antibodies	Blood Clotting Cascade Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Dissolution Of Fibrin Clot Pathway antibodies	Dissolution Of Fibrin Clot Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Platelet Activation, Signaling And Aggregation Pathway antibodies	Platelet Activation, Signaling And Aggregation Pathway Diagram
Platelet Degranulation Pathway antibodies	Platelet Degranulation Pathway Diagram
Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies	Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram

Diseases associated with SERPINF2 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>5 publications with SERPINF2 and Inflammation
Cardiovascular Diseases Antibodies	>3 publications with SERPINF2 and Cardiovascular Diseases
Fibrosis Antibodies	>3 publications with SERPINF2 and Fibrosis
Liver Diseases Antibodies	>3 publications with SERPINF2 and Liver Diseases
Kidney Diseases Antibodies	>2 publications with SERPINF2 and Kidney Diseases
Blood Coagulation Disorders Antibodies	>2 publications with SERPINF2 and Blood Coagulation Disorders
Hyperglycemia Antibodies	>1 publications with SERPINF2 and Hyperglycemia
Hepatitis Antibodies	>1 publications with SERPINF2 and Hepatitis
Carcinoma, Hepatocellular Antibodies	>1 publications with SERPINF2 and Carcinoma, Hepatocellular
Immune System Diseases Antibodies	>1 publications with SERPINF2 and Immune System Diseases

Organs/Tissues associated with SERPINF2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>4 publications with SERPINF2 and Liver
Heart Antibodies	>2 publications with SERPINF2 and Heart
Kidney Antibodies	>2 publications with SERPINF2 and Kidney
Brain Antibodies	>1 publications with SERPINF2 and Brain
Lymph Node Antibodies	>1 publications with SERPINF2 and Lymph Node