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Glucosidase Beta Acid 3 (GBA3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140795

Introduction: Glucosidase Beta Acid 3, also known as GBA3, hydrolyzes various types of glycosides. GBA3 takes part in a nonlysosomal catabolic pathway of glycosylceramide. GBA3 is a protein coding gene which acts as beta-glycosylceramidase.Description: GBA3… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glucosidase Beta Acid 3 (GBA3), Recombinant Protein
Full Product Name
Recombinant Human Glucosidase Beta Acid 3
Product Gene Name
GBA3 recombinant protein
Product Synonym Names
GBA3 Human; Glucosidase Beta Acid 3 Human Recombinant; Cytosolic beta-glucosidase; Cytosolic beta-glucosidase-like protein 1; GBA3; CBG; CBGL1; Glucosidase Beta Acid 3; GH1; Glycoside Hydrolase Family 1; GLUC; KLRP
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMAF PAGF GWAAATAAYQ VEGGWDADGK GPCVWDTFTH QGGERVFKNQ TGDVACGSYT LWEEDLKCIK QLGLTHYRFS LSWSRLLPDG TTGFINQKGI DYYNKIIDDL LKNGVTPIVT LYHFDLPQTL EDQGGWLSEA IIESFDKYAQ FCFSTFGDRV KQWITINEAN VLSVMSYDLG MFPPGIPHFG TGGYQAAHNL IKAHARSWHS YDSLFRKKQK GMVSLSLFAV WLEPADPNSV SDQEAAKRAI TFHLDLFAKP IFIDGDYPEV VKSQIASMSQ KQGYPSSRLP EFTEEEKKMI KGTADFFAVQ YYTTRLIKYQ ENKKGELGIL QDAEIEFFPD PSWKNVDWIY VVPWGVCKLL KYIKDTYNNP VIYITENGFP QSDPAPLDDT QRWEYFRQTF QELFKAIQLD KVNLQVYCAW SLLDNFEWNQ GYSSRFGLFH VDFEDPARPR VPYTSAKEYA KIIRNNGLEA HL.
Host
E Coli
Form/Format
GBA3 protein solution (0.25mg/ml) containing Phosphate Buffered Saline (pH7.4), 20% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Molecular Weight
18,265 Da
OMIM
606619
3D Structure
ModBase 3D Structure for Q9H227

Product Categories/Family for GBA3 recombinant protein

Enzymes

Other Notes

Small volumes of GBA3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GBA3 purchase

MBS140795 is a recombinant protein targeting GBA3. Also known as Recombinant Human Glucosidase Beta Acid 3. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GBA3. It may not necessarily be applicable to this product.

NCBI GI #
190360571
NCBI GeneID
57733
NCBI Accession #
NP_001121904.1
UniProt Primary Accession #
Q9H227
UniProt Secondary Accession #
Q32LY7; Q3MIH4; Q53GG8; Q6NSF4; Q8NHT8; Q9H3T4; Q9H4C6
UniProt Related Accession #
Q9H227
GenBank Nucleotide #
NM_001128432.2
NCBI Official Full Name
cytosolic beta-glucosidase isoform b
NCBI Official Synonym Full Names
glucosylceramidase beta 3 (gene/pseudogene)
NCBI Official Symbol
GBA3
NCBI Official Synonym Symbols
CBG; GLUC; KLRP; CBGL1
UniProt Protein Name
Cytosolic beta-glucosidase
UniProt Synonym Protein Names
Cytosolic beta-glucosidase-like protein 1
Protein Family
Cytosolic beta-glucosidase
UniProt Gene Name
GBA3
UniProt Synonym Gene Names
CBG; CBGL1
UniProt Entry Name
GBA3_HUMAN
NCBI Protein Information
cytosolic beta-glucosidase

UniProt Comments for GBA3

GBA3: Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - starch and sucrose; EC 3.2.1.21; Hydrolase; Other Amino Acids Metabolism - cyanoamino acid

Chromosomal Location of Human Ortholog: 4p15.2

Cellular Component: cytosol

Molecular Function: beta-galactosidase activity; beta-glucosidase activity; glucosylceramidase activity; glycosylceramidase activity

Biological Process: glycoside catabolic process; glycosphingolipid metabolic process; glycosylceramide catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GBA3 recombinant protein

 Products by Pathway  Pathway Diagram
 Cyanoamino Acid Metabolism Pathway antibodies  Cyanoamino Acid Metabolism Pathway Diagram
 Cyanoamino Acid Metabolism Pathway antibodies  Cyanoamino Acid Metabolism Pathway Diagram
 Glycosphingolipid Metabolism Pathway antibodies  Glycosphingolipid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Starch And Sucrose Metabolism Pathway antibodies  Starch And Sucrose Metabolism Pathway Diagram
 Starch And Sucrose Metabolism Pathway antibodies  Starch And Sucrose Metabolism Pathway Diagram

Diseases associated with GBA3 recombinant protein

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >3 publications with GBA3 and Brain Diseases
 Congenital, Hereditary, and Neonatal Diseases and Abnormalities Antibodies  >3 publications with GBA3 and Congenital, Hereditary, and Neonatal Diseases and Abnormalities
 Hypertension Antibodies  >1 publications with GBA3 and Hypertension
 Death Antibodies  >1 publications with GBA3 and Death
 Insulin Resistance Antibodies  >1 publications with GBA3 and Insulin Resistance
 Kidney Diseases Antibodies  >1 publications with GBA3 and Kidney Diseases
 Diabetes Mellitus Antibodies  >1 publications with GBA3 and Diabetes Mellitus

Organs/Tissues associated with GBA3 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with GBA3 and Liver
 Spleen Antibodies  >3 publications with GBA3 and Spleen
 Kidney Antibodies  >3 publications with GBA3 and Kidney
 Intestine Antibodies  >2 publications with GBA3 and Intestine
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