Mouse REN Recombinant Protein – Cat# MBS140862

Renin (REN) Mouse Recombinant Protein

Name: REN Recombinant Protein; Renin; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS140862
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140862

Introduction: Renin is a highly specific endopeptidase which generates angiotensin I from angiotensinogen in the plasma. angiotensin I is an important regulator of blood pressure and electrolyte balance. Renin initiates a cascade of reactions that produce an… More details

$250 / 0.001 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Renin, Recombinant Protein

Full Product Name

Recombinant Mouse Renin

Product Gene Name

REN recombinant protein

Product Synonym Gene Name

mREN

Product Synonym Names

REN Mouse; Renin Mouse Recombinant; Renin-1; Angiotensinogenase; Kidney renin; Ren1; Ren; Ren-A; Ren1c; Ren1d; Rn-1; Rnr

Sequence

LPTRTATFER IPLKKMPSVR EILEERGVDM TRLSAEWGVF TKRPSLTNLT SPVVLTNYLN TQYYGEIGIG TPPQTFKVIF DTGSANLWVP STKCSRLYLA CGIHSLYESS DSSSYMENGS DFTIHYGSGR VKGFLSQDSV TVGGITVTQT FGEVTELPLI PFMLAKFDGV LGMGFPAQAV GGVTPVFDHI LSQGVLKEEV FSVYYNRGSH LLGGEVVLGG SDPQHYQGNF HYVSISKTDS WQITMKGVSV GSSTLLCEEG CAVVVDTGSS FISAPTSSLK LIMQALGAKE KRIEEYVVNC SQVPTLPDIS FDLGGRAYTL SSTDYVLQYP NRRDKLCTLA LHAMDIPPPT GPVWVLGATF IRKFYTEFDR HNNRIGFALA RHHHHHH

Host

Sf9 Baculovirus Cells

Form/Format

REN protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Molecular Weight

44,343 Da

3D Structure

ModBase 3D Structure for P06281

Product Categories/Family for REN recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of REN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for REN purchase

MBS140862 is a recombinant protein targeting REN. Also known as Recombinant Mouse Renin. Host: Sf9 Baculovirus Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for REN. It may not necessarily be applicable to this product.

NCBI GI #

13676837

NCBI GeneID

19701

NCBI Accession #

NP_112469.1

UniProt Primary Accession #

P06281

UniProt Secondary Accession #

P97911; Q543E5; Q62153; Q62154

UniProt Related Accession #

P06281

GenBank Nucleotide #

NM_031192.3

NCBI Official Full Name

renin-1

NCBI Official Synonym Full Names

renin 1 structural

NCBI Official Symbol

Ren1

NCBI Official Synonym Symbols

Ren; Rnr; Rn-1; Ren-1; Ren-A; Ren1c; Ren1d; D19352

UniProt Protein Name

Renin-1

UniProt Synonym Protein Names

Angiotensinogenase; Kidney renin

Protein Family

Protein

UniProt Gene Name

Ren1

UniProt Synonym Gene Names

Ren; Ren-1

UniProt Entry Name

RENI1_MOUSE

NCBI Protein Information

renin-1

UniProt Comments for REN

REN: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Interacts with ATP6AP2. Interaction with ATP6AP2 results in a 5-fold increased efficiency in angiotensinogen processing. Belongs to the peptidase A1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.23.15; Protease; Secreted; Secreted, signal peptide

Cellular Component: cytoplasm; extracellular space; intracellular; lysosome

Molecular Function: aspartic-type endopeptidase activity; endopeptidase activity; insulin-like growth factor receptor binding; peptidase activity; receptor binding

Biological Process: angiotensin maturation; cell maturation; drinking behavior; establishment of blood-nerve barrier; hormone-mediated signaling; kidney development; male gonad development; mesonephros development; proteolysis; regulation of blood pressure; regulation of MAPKKK cascade; renin-angiotensin regulation of aldosterone production; renin-angiotensin regulation of blood volume; response to cAMP; response to drug; response to organic substance

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with REN recombinant protein

Products by Pathway	Pathway Diagram
ACE Inhibitor Pathway antibodies	ACE Inhibitor Pathway Diagram
Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies	Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Peptide Hormone Metabolism Pathway antibodies	Peptide Hormone Metabolism Pathway Diagram
Renin Secretion Pathway antibodies	Renin Secretion Pathway Diagram
Renin Secretion Pathway antibodies	Renin Secretion Pathway Diagram
Renin-angiotensin System Pathway antibodies	Renin-angiotensin System Pathway Diagram
Renin-angiotensin System Pathway antibodies	Renin-angiotensin System Pathway Diagram

Diseases associated with REN recombinant protein

Disease Name	Pubmed Publications
Hypertension Antibodies	>6 publications with REN and Hypertension
Cardiovascular Diseases Antibodies	>4 publications with REN and Cardiovascular Diseases
Disease Models, Animal Antibodies	>4 publications with REN and Disease Models, Animal
Kidney Diseases Antibodies	>3 publications with REN and Kidney Diseases
Neoplasms, Experimental Antibodies	>1 publications with REN and Neoplasms, Experimental
Kidney Neoplasms Antibodies	>1 publications with REN and Kidney Neoplasms
Hemorrhage Antibodies	>1 publications with REN and Hemorrhage
Inflammation Antibodies	>1 publications with REN and Inflammation
Fibrosis Antibodies	>1 publications with REN and Fibrosis

Organs/Tissues associated with REN recombinant protein

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>17 publications with REN and Kidney
Brain Antibodies	>4 publications with REN and Brain
Salivary Gland Antibodies	>3 publications with REN and Salivary Gland
Liver Antibodies	>1 publications with REN and Liver
Testis Antibodies	>1 publications with REN and Testis