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ARP3 Actin-Related Protein 3 (ACTR3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140901

Description: ACTR3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 441 amino acids (1-418 a.a) and having a molecular mass of 49.8kDa. ACTR3 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ARP3 Actin-Related Protein 3 (ACTR3), Recombinant Protein
Full Product Name
Recombinant Human ARP3 Actin-Related Protein 3
Product Gene Name
ACTR3 recombinant protein
Product Synonym Names
ARP3 Actin-Related Protein 3 Homolog (Yeast), ARP3, Actin-Like Protein 3, ARP3 (Actin-Related Protein 3, Yeast) Homolog, Actin-Related Protein 3.
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMAG RLPA CVVDCGTGYT KLGYAGNTEP QFIIPSCIAI KESAKVGDQA QRRVMKGVDD LDFFIGDEAI EKPTYATKWP IRHGIVEDWD LMERFMEQVI FKYLRAEPED HYFLLTEPPL NTPENREYTA EIMFESFNVP GLYIAVQAVL ALAASWTSRQ VGERTLTGTV IDSGDGVTHV IPVAEGYVIG SCIKHIPIAG RDITYFIQQL LRDREVGIPP EQSLETAKAV KERYSYVCPD LVKEFNKYDT DGSKWIKQYT GINAISKKEF SIDVGYERFL GPEIFFHPEF ANPDFTQPIS EVVDEVIQNC PIDVRRPLYK NIVLSGGSTM FRDFGRRLQR DLKRTVDARL KLSEELSGGR LKPKPIDVQV ITHHMQRYAV WFGGSMLAST PEFYQVCHTK KDYEEIGPSI CRHNPVFGVM S
Host
E Coli
Form/Format
Sterile Filtered colorless solution.
ACTR3 protein solution (0.25 mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Molecular Weight
49.8kDa
OMIM
604222
3D Structure
ModBase 3D Structure for P61158

Product Categories/Family for ACTR3 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of ACTR3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ACTR3 purchase

MBS140901 is a recombinant protein targeting ACTR3. Also known as Recombinant Human ARP3 Actin-Related Protein 3. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ACTR3. It may not necessarily be applicable to this product.

NCBI GI #
5031573
NCBI GeneID
10096
NCBI Accession #
NP_005712.1
UniProt Primary Accession #
P61158
UniProt Secondary Accession #
P32391; Q53QM2
UniProt Related Accession #
P61158
GenBank Nucleotide #
NM_005721.4
NCBI Official Full Name
actin-related protein 3 isoform 1
NCBI Official Synonym Full Names
ARP3 actin-related protein 3 homolog (yeast)
NCBI Official Symbol
ACTR3
NCBI Official Synonym Symbols
ARP3
UniProt Protein Name
Actin-related protein 3
UniProt Synonym Protein Names
Actin-like protein 3
UniProt Gene Name
ACTR3
UniProt Synonym Gene Names
ARP3
UniProt Entry Name
ARP3_HUMAN
NCBI Protein Information
actin-related protein 3

UniProt Comments for ACTR3

Arp3: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis. Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with WHDC1. Belongs to the actin family. ARP3 subfamily.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q14.1

Cellular Component: actin cytoskeleton; Arp2/3 protein complex; cytosol; focal adhesion; membrane

Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton

Biological Process: cell motility; ephrin receptor signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ACTR3 recombinant protein

 Reference Product  PubMed Publications
 ACTR2 recombinant protein  >157 publications with ACTR3 and ACTR2
 WASL recombinant protein  >45 publications with ACTR3 and WASL
 ARPC5 recombinant protein  >4 publications with ACTR3 and ARPC5
 ARPC1B recombinant protein  >3 publications with ACTR3 and ARPC1B
 ARPC5L recombinant protein  >2 publications with ACTR3 and ARPC5L
 ARPC1A recombinant protein  >2 publications with ACTR3 and ARPC1A
 ARPC2 recombinant protein  >2 publications with ACTR3 and ARPC2
 ARPC3 recombinant protein  >2 publications with ACTR3 and ARPC3
 ARPC4 recombinant protein  >1 publications with ACTR3 and ARPC4

Pathways associated with ACTR3 recombinant protein

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 CDC42 Signaling Events Pathway antibodies  CDC42 Signaling Events Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPHB-mediated Forward Signaling Pathway antibodies  EPHB-mediated Forward Signaling Pathway Diagram
 ErbB1 Downstream Signaling Pathway antibodies  ErbB1 Downstream Signaling Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram

Diseases associated with ACTR3 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >7 publications with ACTR3 and Neoplasm Metastasis
 Nervous System Diseases Antibodies  >2 publications with ACTR3 and Nervous System Diseases
 Abnormalities, Multiple Antibodies  >1 publications with ACTR3 and Abnormalities, Multiple
 Urogenital Abnormalities Antibodies  >1 publications with ACTR3 and Urogenital Abnormalities
 Neurobehavioral Manifestations Antibodies  >1 publications with ACTR3 and Neurobehavioral Manifestations
 Poisoning Antibodies  >1 publications with ACTR3 and Poisoning
 Proteinuria Antibodies  >1 publications with ACTR3 and Proteinuria
 Fibrosis Antibodies  >1 publications with ACTR3 and Fibrosis
 Neoplasms, Experimental Antibodies  >1 publications with ACTR3 and Neoplasms, Experimental
 Necrosis Antibodies  >1 publications with ACTR3 and Necrosis

Organs/Tissues associated with ACTR3 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >42 publications with ACTR3 and Nerve
 Blood Antibodies  >25 publications with ACTR3 and Blood
 Muscle Antibodies  >15 publications with ACTR3 and Muscle
 Brain Antibodies  >13 publications with ACTR3 and Brain
 Liver Antibodies  >4 publications with ACTR3 and Liver
 Stomach Antibodies  >4 publications with ACTR3 and Stomach
 Lung Antibodies  >3 publications with ACTR3 and Lung
 Kidney Antibodies  >3 publications with ACTR3 and Kidney
 Bone Antibodies  >3 publications with ACTR3 and Bone
 Heart Antibodies  >3 publications with ACTR3 and Heart
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