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Pachytene Checkpoint Protein 2 Homolog (TRIP13) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1409538

This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in… More details

$1185 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Pachytene checkpoint protein 2 homolog (Trip13), Recombinant Protein
Full Product Name
Recombinant Rat Pachytene checkpoint protein 2 homolog (Trip13)
Product Gene Name
Trip13 recombinant protein
Product Synonym Gene Name
Trip13
Sequence
MDDAVGDLKQ ALPCVAESPA VHVEVLQRSG STAKKEDIKQ SVYRLLKRHN IVFGDYVWTE FDEPFLTRNV QSVSIVDTEL KAKDPQPIDL SACTIALHIF QLNEEGPSSE NLDEETENII AASHWVLPAA EFHGLWDSLV YDVEVKSHLL DYVMTTLLFS DKNVDSNLIT WNRVVLLHGP PGTGKTSLCK ALAQKLTIRL SSRYRYGQLI EINSHSLFSK WFSESGKLVT KMFQKIQDLI DDKEALVFVL IDEVESLTAA RNACRAGAEP SDAIRVVNAV LTQIDQIKRH SNVVILTTSN ITEKIDVAFV DRADIKQYIG PPSAAAIFKI YLSCLEELMK CQIIYPRQQL LTLRELEMIG FIENNVSKLS LLLSEISRKS EGLSGRVLRK LPFLAHALYI QAPSVTIEGF LQALSLAVDK QFEEKKKLSA HV
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
48,434 Da
Sequence Positions
1-432, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q5XHZ9
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Trip13 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Trip13 purchase

MBS1409538 is a recombinant protein targeting Trip13. Also known as Recombinant Rat Pachytene checkpoint protein 2 homolog (Trip13). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Trip13. It may not necessarily be applicable to this product.

NCBI GI #
58865438
NCBI GeneID
292206
NCBI Accession #
NP_001011930.1
UniProt Primary Accession #
Q5XHZ9
UniProt Related Accession #
Q5XHZ9
GenBank Nucleotide #
NM_001011930.1
NCBI Official Full Name
pachytene checkpoint protein 2 homolog
NCBI Official Synonym Full Names
thyroid hormone receptor interactor 13
NCBI Official Symbol
Trip13
UniProt Protein Name
Pachytene checkpoint protein 2 homolog
UniProt Synonym Protein Names
Thyroid hormone receptor interactor 13; Thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP-13
UniProt Gene Name
Trip13
UniProt Synonym Gene Names
Pch2; TR-interacting protein 13; TRIP-13
NCBI Protein Information
pachytene checkpoint protein 2 homolog

UniProt Comments for Trip13

Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes. Plays a role in mitotic spindle assembly checkpoint (SAC) activation ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Trip13 recombinant protein

 Reference Product  PubMed Publications
 Hormad1 recombinant protein  >1 publications with Trip13 and Hormad1
 Spo11 recombinant protein  >1 publications with Trip13 and Spo11
 Rad51 recombinant protein  >1 publications with Trip13 and Rad51

Diseases associated with Trip13 recombinant protein

 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >1 publications with Trip13 and Prostatic Neoplasms
 Infertility, Male Antibodies  >1 publications with Trip13 and Infertility, Male
 Carcinoma, Squamous Cell Antibodies  >1 publications with Trip13 and Carcinoma, Squamous Cell
 Infertility, Female Antibodies  >1 publications with Trip13 and Infertility, Female
 Lung Neoplasms Antibodies  >1 publications with Trip13 and Lung Neoplasms

Organs/Tissues associated with Trip13 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with Trip13 and Lung
 Ovary Antibodies  >1 publications with Trip13 and Ovary
 Prostate Antibodies  >1 publications with Trip13 and Prostate
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