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Neutrophil-Activating Protein A (HP-NAP) Helicobacter Pylori Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140954

Introduction: HP-NAP protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, thus preventing hydroxyl radical production by the Fenton… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Neutrophil-activating protein A (HP-NAP), Recombinant Protein
Full Product Name
Recombinant Helicobacter Pylori Neutrophil-activating protein A
Product Gene Name
HP-NAP recombinant protein
Product Synonym Names
HP-NAP; Neutrophil-activating protein A Helicobacter Pylori Recombinant; DNA protection during starvation protein; Bacterioferritin; HP-NAP; Neutrophil-activating protein A; NAP A; dps; napA
Sequence
MKHHHHH HASMKT FEILKHL QADAIVLFMK VHNFHWNVKG TDFFNVHKAT EEIYEEFADM FDDLAERIVQ LGHHPLVTLS EAIKLTRVKE ETKTSFHSKD IFKEILEDYK YLEKEFKELS NTAEKEGDKV TVTYADDQLA KLQKSIWMLQ AHLA.
Host
E Coli
Form/Format
HP-NAP was filtered (0.4 um) and lyophilized in 20mM Tris buffer and 50mM NaCl, pH 7.5.
Filtered White lyophilized (freeze-dried) powder.
Purity/Purification
Purity as determined by densitometric image analysis is greater than 95%.
Preparation and Storage
Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
Molecular Weight
16,933 Da
3D Structure
ModBase 3D Structure for P43313
Solubility
It is recommended to add 200 ul of deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. HP-NAP is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Product Categories/Family for HP-NAP recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of HP-NAP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HP-NAP purchase

MBS140954 is a recombinant protein targeting HP-NAP. Also known as Recombinant Helicobacter Pylori Neutrophil-activating protein A. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for HP-NAP. It may not necessarily be applicable to this product.

NCBI GI #
15644871
NCBI GeneID
898765
NCBI Accession #
NP_207041.1
UniProt Primary Accession #
P43313
UniProt Secondary Accession #
Q64EY0; Q932V4; Q9F7B4; Q9F7B5; Q9F7B6; Q9F7B7; Q9F7B8; Q9F7B9; Q9K2M7; Q9K2U7; Q9KW50
UniProt Related Accession #
P43313
GenBank Nucleotide #
NC_000915.1
NCBI Official Full Name
DNA protection during starvation protein
NCBI Official Symbol
HP0243
UniProt Protein Name
DNA protection during starvation protein
UniProt Synonym Protein Names
Bacterioferritin; HP-NAP; Neutrophil-activating protein A; NAP A
UniProt Gene Name
dps
UniProt Synonym Gene Names
napA; NAP A
UniProt Entry Name
DPS_HELPY
NCBI Protein Information
DNA protection during starvation protein

UniProt Comments for HP-NAP

Protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, which prevents hydroxyl radical production by the Fenton reaction (). Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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