Human VNN1 Recombinant Protein – Cat# MBS140997

Vanin-1 (VNN1) Human Recombinant Protein

Name: VNN1 Recombinant Protein; Vanin-1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS140997
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140997

Introduction: Vanin 1 (VNN1) belongs to the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. This family includes secreted and membrane-associated proteins, a few of which have been described to… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Vanin-1 (VNN1), Recombinant Protein

Full Product Name

Recombinant Human Vanin-1

Product Gene Name

VNN1 recombinant protein

Product Synonym Names

VNN1 Human; Vanin 1 Human Recombinant; Vanin 1; Vascular Non-Inflammatory Molecule 1; Pantetheine Hydrolase; EC 3.5.1.92; Vanin-1; HDLCQ8; Tiff66; Pantetheinase; Vannin 1; EC 3.5.1; VNN1

Sequence

MKHHHHH HASQDT FTAAVYE HAAILPNATL TPVSREEALA LMNRNLDILE GAITSAADQG AHIIVTPEDA IYGWNFNRDS LYPYLEDIPD PEVNWIPCNN RNRFGQTPVQ ERLSCLAKNN SIYVVANIGD KKPCDTSDPQ CPPDGRYQYN TDVVFDSQGK LVARYHKQNL FMGENQFNVP KEPEIVTFNT TFGSFGIFTC FDILFHDPAV TLVKDFHVDT IVFPTAWMNV LPHLSAVEFH SAWAMGMRVN FLASNIHYPS KKMTGSGIYA PNSSRAFHYD MKTEEGKLLL SQLDSHPSHS AVVNWTSYAS SIEALSSGNK EFKGTVFFDE FTFVKLTGVA GNYTVCQKDL CCHLSYKMSE NIPNEVYALG AFDGLHTVEG RYYLQICTLL KCKTTNLNTC GDSAETASTR FEMFSLSGTF GTQYVFPEVL LSENQLAPGE FQVSTDGRLF SLKPTSGPVL TVTLFGRLYE KDWASNASSG .

Host

E Coli

Form/Format

VNN1 was filtered (0.4 um) and lyophilized in 20mM Tris buffer, 50mM NaCl and 0.1% amisoft CS-22, pH 7.5.
Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Purity as determined by densitometric image analysis is greater than 95%.

Preparation and Storage

Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.

Molecular Weight

57,012 Da

OMIM

603570

3D Structure

ModBase 3D Structure for O95497

Solubility

It is recommended to add 200 ul of deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. VNN1 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Product Categories/Family for VNN1 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of VNN1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VNN1 purchase

MBS140997 is a recombinant protein targeting VNN1. Also known as Recombinant Human Vanin-1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for VNN1. It may not necessarily be applicable to this product.

NCBI GI #

223633991

NCBI GeneID

8876

NCBI Accession #

NP_004657.2

UniProt Primary Accession #

O95497

UniProt Secondary Accession #

Q4JFW6; Q4VAS7; Q4VAS8; Q4VAS9; Q9UF16; Q9UJF4; A8K310

UniProt Related Accession #

O95497

GenBank Nucleotide #

NM_004666.2

NCBI Official Full Name

pantetheinase

NCBI Official Synonym Full Names

vanin 1

NCBI Official Symbol

VNN1

NCBI Official Synonym Symbols

HDLCQ8; Tiff66

UniProt Protein Name

Pantetheinase

UniProt Synonym Protein Names

Pantetheine hydrolase; Tiff66; Vascular non-inflammatory molecule 1; Vanin-1

Protein Family

Pantetheinase

UniProt Gene Name

VNN1

UniProt Synonym Gene Names

Vanin-1

UniProt Entry Name

VNN1_HUMAN

NCBI Protein Information

pantetheinase

UniProt Comments for VNN1

VNN1: Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Belongs to the CN hydrolase family. BTD/VNN subfamily.

Protein type: Cell adhesion; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 3.5.1.92; Hydrolase; Membrane protein, GPI anchor; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 6q23-q24

Cellular Component: integral to membrane

Molecular Function: pantetheine hydrolase activity

Biological Process: acute inflammatory response; biotin metabolic process; cell motility; cell-cell adhesion; central nervous system development; chronic inflammatory response; inflammatory response; innate immune response; pantothenate metabolic process; positive regulation of T cell differentiation in the thymus; response to oxidative stress

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with VNN1 recombinant protein

Products by Pathway	Pathway Diagram
Pantothenate And CoA Biosynthesis Pathway antibodies	Pantothenate And CoA Biosynthesis Pathway Diagram
Pantothenate And CoA Biosynthesis Pathway antibodies	Pantothenate And CoA Biosynthesis Pathway Diagram

Diseases associated with VNN1 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>8 publications with VNN1 and Inflammation
Liver Diseases Antibodies	>5 publications with VNN1 and Liver Diseases
Cardiovascular Diseases Antibodies	>5 publications with VNN1 and Cardiovascular Diseases
Fatty Liver Antibodies	>4 publications with VNN1 and Fatty Liver
Hypertension Antibodies	>3 publications with VNN1 and Hypertension
Blood Coagulation Disorders Antibodies	>2 publications with VNN1 and Blood Coagulation Disorders
Poisoning Antibodies	>2 publications with VNN1 and Poisoning
Hyperplasia Antibodies	>2 publications with VNN1 and Hyperplasia
Hemorrhage Antibodies	>2 publications with VNN1 and Hemorrhage
Fibrosis Antibodies	>1 publications with VNN1 and Fibrosis

Organs/Tissues associated with VNN1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>20 publications with VNN1 and Blood
Liver Antibodies	>12 publications with VNN1 and Liver
Ovary Antibodies	>5 publications with VNN1 and Ovary
Bone Antibodies	>4 publications with VNN1 and Bone
Bone Marrow Antibodies	>4 publications with VNN1 and Bone Marrow
Muscle Antibodies	>2 publications with VNN1 and Muscle
Intestine Antibodies	>1 publications with VNN1 and Intestine
Kidney Antibodies	>1 publications with VNN1 and Kidney