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Elongator Acetyltransferase Complex Subunit 4 (ELP4) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS141053

Introduction: Elongator Acetyltransferase Complex Subunit 4, also known as ELP4 is a protein coding gene which is a subunit of the RNA polymerase II elongator complex. ELP4 complements phenotypes of yeast ELP4 deletion mutants and is related to Rolandic… More details

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Product Overview

Online Datasheet in PDF
Product Name
Elongator Acetyltransferase Complex Subunit 4 (ELP4), Recombinant Protein
Full Product Name
Recombinant Human Elongator Acetyltransferase Complex Subunit 4
Product Gene Name
ELP4 recombinant protein
Product Synonym Names
ELP4 Human; Elongator Acetyltransferase Complex Subunit 4 Human Recombinant; Elongator complex protein 4; ELP4; Elongator Acetyltransferase Complex Subunit 4; hELP4; PAX6 neighbor gene protein; C11orf19; PAXNEB; dJ68P15A.1; PAX6NEB
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMAA VATC GSVAASTGSA VATASKSNVT SFQRRGPRAS VTNDSGPRLV SIAGTRPSVR NGQLLVSTGL PALDQLLGGG LAVGTVLLIE EDKYNIYSPL LFKYFLAEGI VNGHTLLVAS AKEDPANILQ ELPAPLLDDK CKKEFDEDVY NHKTPESNIK MKIAWRYQLL PKMEIGPVSS SRFGHYYDAS KRMPQELIEA SNWHGFFLPE KISSTLKVEP CSLTPGYTKL LQFIQNIIYE EGFDGSNPQK KQRNILRIGI QNLGSPLWGD DICCAENGGN SHSLTKFLYV LRGLLRTSLS ACIITMPTHL IQNKAIIARV TTLSDVVVGL ESFIGSERET NPLYKDYHGL IHIRQIPRLN NLICDESDVK DLAFKLKRKL FTIERLHLPP DLSDTVSRSS KMDLAESAKR LGPGCGMMAG GKKHLDF.
Host
E Coli
Form/Format
ELP4 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 80.0% as determined by SDS-PAGE.
Molecular Weight
52,765 Da
OMIM
606985
3D Structure
ModBase 3D Structure for Q96EB1

Product Categories/Family for ELP4 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of ELP4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ELP4 purchase

MBS141053 is a recombinant protein targeting ELP4. Also known as Recombinant Human Elongator Acetyltransferase Complex Subunit 4. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ELP4. It may not necessarily be applicable to this product.

NCBI GI #
570359562
NCBI GeneID
26610
NCBI Accession #
NP_001275654.1
UniProt Primary Accession #
Q96EB1
UniProt Secondary Accession #
Q9H4E8; Q9NX11; B4E3W0; E7EPZ6
UniProt Related Accession #
Q96EB1
GenBank Nucleotide #
NM_001288725.1
NCBI Official Full Name
elongator complex protein 4 isoform 2
NCBI Official Synonym Full Names
elongator acetyltransferase complex subunit 4
NCBI Official Symbol
ELP4
NCBI Official Synonym Symbols
AN; hELP4; PAXNEB; PAX6NEB; C11orf19; dJ68P15A.1
UniProt Protein Name
Elongator complex protein 4
UniProt Synonym Protein Names
PAX6 neighbor gene protein
Protein Family
Elongator complex protein
UniProt Gene Name
ELP4
UniProt Synonym Gene Names
C11orf19; PAXNEB; hELP4
UniProt Entry Name
ELP4_HUMAN
NCBI Protein Information
elongator complex protein 4

UniProt Comments for ELP4

ELP4: Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Belongs to the ELP4 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytoplasm; Elongator holoenzyme complex; histone acetyltransferase complex; nucleoplasm; transcription elongation factor complex

Molecular Function: histone acetyltransferase activity; phosphorylase kinase regulator activity; protein binding

Biological Process: regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter

Disease: Aniridia; Aniridia 2
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ELP4 recombinant protein

 Reference Product  PubMed Publications
 ELP6 recombinant protein  >12 publications with ELP4 and ELP6
 ELP3 recombinant protein  >10 publications with ELP4 and ELP3
 ELP5 recombinant protein  >9 publications with ELP4 and ELP5
 ELP2 recombinant protein  >9 publications with ELP4 and ELP2

Pathways associated with ELP4 recombinant protein

 Products by Pathway  Pathway Diagram
 Chromatin Modifying Enzymes Pathway antibodies  Chromatin Modifying Enzymes Pathway Diagram
 Chromatin Organization Pathway antibodies  Chromatin Organization Pathway Diagram
 HATs Acetylate Histones Pathway antibodies  HATs Acetylate Histones Pathway Diagram

Diseases associated with ELP4 recombinant protein

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >7 publications with ELP4 and Congenital Abnormalities
 Epilepsy, Temporal Lobe Antibodies  >1 publications with ELP4 and Epilepsy, Temporal Lobe
 Kidney Diseases Antibodies  >1 publications with ELP4 and Kidney Diseases
 Abnormalities, Multiple Antibodies  >1 publications with ELP4 and Abnormalities, Multiple
 Neurobehavioral Manifestations Antibodies  >1 publications with ELP4 and Neurobehavioral Manifestations

Organs/Tissues associated with ELP4 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >9 publications with ELP4 and Eye
 Brain Antibodies  >8 publications with ELP4 and Brain
 Blood Antibodies  >6 publications with ELP4 and Blood
 Skin Antibodies  >1 publications with ELP4 and Skin
 Pancreas Antibodies  >1 publications with ELP4 and Pancreas
 Embryonic Tissue Antibodies  >1 publications with ELP4 and Embryonic Tissue
 Kidney Antibodies  >1 publications with ELP4 and Kidney
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