Haptoglobin Related (HPR) ELISA Kit for Cavy

Name: Cavy HPR ELISA Kit; Haptoglobin Related; MyBioSource
Brand: MyBioSource
SKU: MBS014108
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS014108

MBS014108 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Haptoglobin Related Protein (HPR) ELISA Kit target analytes in biological samples. The concentration gradients of the… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Haptoglobin Related Protein (HPR), ELISA Kit

Full Product Name

Cavy Haptoglobin Related Protein ELISA Kit

Product Gene Name

HPR elisa kit

Species Reactivity

Cavy

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

39,030 Da

Chromosome Location

Chromosome: 16; NC_000016.9 (72097125..72111145). Location: 16q22.1

OMIM

140210

3D Structure

ModBase 3D Structure for P00739

Other Notes

Small volumes of HPR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HPR. It may not necessarily be applicable to this product.

NCBI GI #

45580723

NCBI GeneID

3250

NCBI Accession #

NP_066275.3

UniProt Primary Accession #

P00739

UniProt Secondary Accession #

Q7LE20; Q92658; Q92659; Q9ULB0

UniProt Related Accession #

P00739

GenBank Nucleotide #

NM_020995.3

NCBI Official Full Name

haptoglobin-related protein

NCBI Official Synonym Full Names

haptoglobin-related protein

NCBI Official Symbol

HPR

NCBI Official Synonym Symbols

HP; A-259H10.2

UniProt Protein Name

Haptoglobin-related protein

Protein Family

Glycerate dehydrogenase

UniProt Gene Name

HPR

UniProt Entry Name

HPTR_HUMAN

NCBI Protein Information

haptoglobin-related protein; Haptoglobin-related locus

NCBI Summary for HPR

This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]

UniProt Comments for HPR

HPR: a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: extracellular region

Molecular Function: hemoglobin binding; catalytic activity

Biological Process: receptor-mediated endocytosis; metabolic process

Research Articles on HPR

1. Our analysis illustrates the complex interplay between functions and haplotypes of adjacent genes, environmental context and natural selection, and offers insights into potential use of haptoglobin or haptoglobin-related protein as therapeutic agents.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HPR elisa kit

Reference Product	PubMed Publications
HBD elisa kit	>4 publications with HPR and HBD
APOA1 elisa kit	>3 publications with HPR and APOA1
ASGR1 elisa kit	>1 publications with HPR and ASGR1

Pathways associated with HPR elisa kit

Products by Pathway	Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies	Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
Scavenging Of Heme From Plasma Pathway antibodies	Scavenging Of Heme From Plasma Pathway Diagram

Diseases associated with HPR elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>406 publications with HPR and Neoplasms
Breast Neoplasms Antibodies	>121 publications with HPR and Breast Neoplasms
Neoplasms, Experimental Antibodies	>92 publications with HPR and Neoplasms, Experimental
Drug Toxicity Antibodies	>77 publications with HPR and Drug Toxicity
Mammary Neoplasms, Animal Antibodies	>44 publications with HPR and Mammary Neoplasms, Animal
Ovarian Neoplasms Antibodies	>37 publications with HPR and Ovarian Neoplasms
Kidney Diseases Antibodies	>34 publications with HPR and Kidney Diseases
Immune System Diseases Antibodies	>28 publications with HPR and Immune System Diseases
Liver Neoplasms Antibodies	>24 publications with HPR and Liver Neoplasms
Lymphoma Antibodies	>22 publications with HPR and Lymphoma

Organs/Tissues associated with HPR elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>77 publications with HPR and Liver
Brain Antibodies	>52 publications with HPR and Brain
Lung Antibodies	>49 publications with HPR and Lung
Heart Antibodies	>42 publications with HPR and Heart