Human PSMD5 Recombinant Protein – Cat# MBS141108

Proteasome 26s Subunit (PSMD5) Human Recombinant Protein

Name: PSMD5 Recombinant Protein; Proteasome 26s Subunit; Human; MyBioSource
Brand: MyBioSource
SKU: MBS141108
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS141108

Introduction: Proteasome 26S Subunit, Non-ATPase 5, also known as PSMD5 is a member of the proteasome subunit S5B/HSM3 family. The 26S proteasome is an enzymatic complex which degrades ubiquitinated proteins in eukaryotic cells. Furthermore, PSMD5 acts as a… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Proteasome 26S Subunit (PSMD5), Recombinant Protein

Full Product Name

Recombinant Human Proteasome 26S Subunit, Non-ATPase 5

Product Gene Name

PSMD5 recombinant protein

Product Synonym Names

PSMD5 Human; Proteasome 26S Subunit, Non-ATPase 5 Human Recombinant; PSMD5; Proteasome (Prosome; Macropain) 26S Subunit; Non-ATPase; 526S Protease Subunit S5 Basic;26S Proteasome Subunit S5B;S5B;26S Proteasome Non-ATPase Regulatory Subunit 5;KIAA0072

Sequence

MGSSHHH HHH SSGLVPRGSH MGSEFM AAQA LALLREVARL EAPLEELRAL HSVLQAVPLN ELRQQAAELR LGPLFSLLNE NHREKTTLCV SILERLLQAM EPVHVARNLR VDLQRGLIHP DDSVKILTLS QIGRIVENSD AVTEILNNAE LLKQIVYCIG GENLSVAKAA IKSLSRISLT QAGLEALFES NLLDDLKSVM KTNDIVRYRV YELIIEISSV SPESLNYCTT SGLVTQLLRE LTGEDVLVRA TCIEMVTSLA YTHHGRQYLA QEGVIDQISN IIVGADSDPF SSFYLPGFVK FFGNLAVMDS PQQICERYPI FVEKVFEMIE SQDPTMIGVA VDTVGILGSN VEGKQVLQKT GTRFERLLMR IGHQSKNAPV ELKIRCLDAI SSLLYLPPEQ QTDDLLRMTE SWFSSLSRDP LELFRGISSQ PFPELHCAAL KVFTAIANQP WAQKLMFNSP GFVEYVVDRS VEHDKASKDA KYELVKALAN SKTIAEIFGN PNYLRLRTYL SEGPYYVKPV STTAVEGAE

Host

E Coli

Form/Format

PSMD5 protein solution (1mg/ml) containing Phosphate Buffered Saline (pH7.4) and 10% glycerol.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Molecular Weight

51,312 Da

OMIM

604452

3D Structure

ModBase 3D Structure for Q16401

Product Categories/Family for PSMD5 recombinant protein

Enzymes

Other Notes

Small volumes of PSMD5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSMD5 purchase

MBS141108 is a recombinant protein targeting PSMD5. Also known as Recombinant Human Proteasome 26S Subunit, Non-ATPase 5. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PSMD5. It may not necessarily be applicable to this product.

NCBI GI #

394025672

NCBI GeneID

5711

NCBI Accession #

NP_001257356.1

UniProt Primary Accession #

Q16401

UniProt Secondary Accession #

Q15045; Q4VXG8; B4DZM8

UniProt Related Accession #

Q16401

GenBank Nucleotide #

NM_001270427.1

NCBI Official Full Name

26S proteasome non-ATPase regulatory subunit 5 isoform 2

NCBI Official Synonym Full Names

proteasome 26S subunit, non-ATPase 5

NCBI Official Symbol

PSMD5

NCBI Official Synonym Symbols

S5B

UniProt Protein Name

26S proteasome non-ATPase regulatory subunit 5

UniProt Synonym Protein Names

26S protease subunit S5 basic; 26S proteasome subunit S5B

Protein Family

26S proteasome non-ATPase regulatory

UniProt Gene Name

PSMD5

UniProt Synonym Gene Names

KIAA0072

UniProt Entry Name

PSMD5_HUMAN

NCBI Protein Information

26S proteasome non-ATPase regulatory subunit 5

UniProt Comments for PSMD5

PSMD5: Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5. Belongs to the proteasome subunit S5B/HSM3 family.

Protein type: Protease; Proteasome complex

Chromosomal Location of Human Ortholog: 9q33.2

Cellular Component: cytosol; nucleoplasm; proteasome complex

Molecular Function: protein binding

Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; MAPKKK cascade; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of amino acid metabolic process; regulation of mRNA stability; stimulatory C-type lectin receptor signaling pathway; T cell receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; Wnt receptor signaling pathway, planar cell polarity pathway

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PSMD5 recombinant protein

Products by Pathway	Pathway Diagram
APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies	APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies	APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies	APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies	APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway antibodies	APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway Diagram
ARMS-mediated Activation Pathway antibodies	ARMS-mediated Activation Pathway Diagram
AUF1 (hnRNP D0) Binds And Destabilizes MRNA Pathway antibodies	AUF1 (hnRNP D0) Binds And Destabilizes MRNA Pathway Diagram
Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies	Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
Activation Of NF-kappaB In B Cells Pathway antibodies	Activation Of NF-kappaB In B Cells Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram

Diseases associated with PSMD5 recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>1 publications with PSMD5 and Necrosis

Organs/Tissues associated with PSMD5 recombinant protein

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>1 publications with PSMD5 and Eye