Human CRTAM Recombinant Protein – Cat# MBS141184

Cytotoxic and Regulatory T Cell Molecule (CRTAM) Human Recombinant Protein

Name: CRTAM Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS141184
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS141184

Introduction: Cytotoxic and Regulatory T Cell Molecule, also known as CRTAM belongs to the immunoglobulin superfamily which complies with the structural characteristics of the JAM family and is phylogenetically more closely related to nectin-like proteins.… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cytotoxic And Regulatory T Cell Molecule (CRTAM), Recombinant Protein

Full Product Name

Recombinant Human Cytotoxic And Regulatory T Cell Molecule

Product Gene Name

CRTAM recombinant protein

Product Synonym Names

CRTAM Human; Cytotoxic and Regulatory T Cell Molecule Human Recombinant; Cytotoxic and Regulatory T Cell Molecule; Class I MHC Restricted T Cell Associated Molecule; Class-I MHC-Restricted T-Cell-Associated Molecule; Class-I MHC-Restricted T Cell Associated Molecule; Cytotoxic and Regulatory T-Cell Molecule; CD355 Antigen; CD355

Sequence

SLTNHTETIT VEEGQTLTLK CVTSLRKNSS LQWLTPSGFT IFLNEYPALK NSKYQLLHHS ANQLSITVPN VTLQDEGVYK CLHYSDSVST KEVKVIVLAT PFKPILEASV IRKQNGEEHV VLMCSTMRSK PPPQITWLLG NSMEVSGGTL HEFETDGKKC NTTSTLIIHT YGKNSTVDCI IRHRGLQGRK LVAPFRFEDL VTDEETASDA LERNSLSSQD PQQPTSTVSV TEDSSTSEID KEEKEQTTQD PDLTTEANPQ YLGLARKKSG LEHHHHH H

Host

Sf9 Insect Cells

Form/Format

CRTAM protein solution (1mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.
Sterile filtered colorless solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Molecular Weight

22,256 Da

OMIM

612597

3D Structure

ModBase 3D Structure for O95727

Product Categories/Family for CRTAM recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of CRTAM recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRTAM purchase

MBS141184 is a recombinant protein targeting CRTAM. Also known as Recombinant Human Cytotoxic And Regulatory T Cell Molecule. Host: Sf9 Insect Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for CRTAM. It may not necessarily be applicable to this product.

NCBI GI #

755571554

NCBI GeneID

56253

NCBI Accession #

NP_001291711.1

UniProt Primary Accession #

O95727

UniProt Secondary Accession #

Q59EI1; Q6IRX2

UniProt Related Accession #

O95727

GenBank Nucleotide #

NM_001304782.1

NCBI Official Full Name

cytotoxic and regulatory T-cell molecule Isoform 2

NCBI Official Synonym Full Names

cytotoxic and regulatory T-cell molecule

NCBI Official Symbol

CRTAM

NCBI Official Synonym Symbols

CD355

UniProt Protein Name

Cytotoxic and regulatory T-cell molecule

UniProt Synonym Protein Names

Class-I MHC-restricted T-cell-associated molecule; CD_antigen: CD355

Protein Family

Cytotoxic and regulatory T-cell molecule

UniProt Gene Name

CRTAM

UniProt Entry Name

CRTAM_HUMAN

NCBI Protein Information

cytotoxic and regulatory T-cell molecule

UniProt Comments for CRTAM

CRTAM: Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. Belongs to the nectin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q24.1

Cellular Component: cell-cell adherens junction; integral to plasma membrane; plasma membrane

Molecular Function: cell adhesion molecule binding; protein homodimerization activity; receptor activity; receptor binding

Biological Process: activated T cell proliferation; cell recognition; detection of stimulus; detection of tumor cell; heterophilic cell adhesion; homophilic cell adhesion; positive regulation of cytokine secretion; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; regulation of immune response; T cell mediated cytotoxicity

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CRTAM recombinant protein

Reference Product	PubMed Publications
CADM1 recombinant protein	>9 publications with CRTAM and CADM1
TIGIT recombinant protein	>2 publications with CRTAM and TIGIT
SCRIB recombinant protein	>1 publications with CRTAM and SCRIB

Pathways associated with CRTAM recombinant protein

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies	Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram

Diseases associated with CRTAM recombinant protein

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>3 publications with CRTAM and Lung Diseases
Lung Neoplasms Antibodies	>2 publications with CRTAM and Lung Neoplasms
Necrosis Antibodies	>2 publications with CRTAM and Necrosis
Neoplasms, Experimental Antibodies	>1 publications with CRTAM and Neoplasms, Experimental
Cell Transformation, Neoplastic Antibodies	>1 publications with CRTAM and Cell Transformation, Neoplastic
Inflammation Antibodies	>1 publications with CRTAM and Inflammation

Organs/Tissues associated with CRTAM recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>28 publications with CRTAM and Blood
Thymus Antibodies	>4 publications with CRTAM and Thymus
Lung Antibodies	>4 publications with CRTAM and Lung
Brain Antibodies	>4 publications with CRTAM and Brain
Spleen Antibodies	>3 publications with CRTAM and Spleen
Muscle Antibodies	>1 publications with CRTAM and Muscle