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PDZ and LIM Domain Protein 5 (PDLIM5) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1412368

This protein is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein… More details

$1385 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PDZ and LIM domain protein 5 (Pdlim5), Recombinant Protein
Full Product Name
Recombinant Rat PDZ and LIM domain protein 5 (Pdlim5)
Product Gene Name
Pdlim5 recombinant protein
Product Synonym Gene Name
Pdlim5
Sequence
SNYNVSLVGP APWGFRLQGG KDFNMPLTIS SLKDGGKASQ AHVRIGDVVL SIDGISAQGM THLEAQNKIK ACTGSLNMTL QRASAAAKSE PVAVQKGEPK EVVKPVPITS PAVSKVTSTT NMAYNKVPRP FGSVSSPKVT SIPSPSSAFT PAHAATSSHA SPPPVAAVTP PPLSASGLHA SANPSAAQCS SPPNTGKPAV HVPRQPTVTS VCSESAQELA EGQRRGSQGD IKQQNGPPRK HIVERNTEFY HIPTHSDASK KRLIEDTEDW RPRTGTTQSR SFRILAQITG TEHLKESEND NAKKANSTPE PSQQSASPLS AAESLESPGS NRPVVAGLRS AAAFKPVGST SVKSPSWQRP NQAAPSTGRI SNSASSSGTG APMKPAVGPP QPSDQDTLVQ RAEHIPAGKR TPMCAHCNQA IRGPFLVALG KSWHPEEFNC AHCKNTMAYI GFVEEKGALY CELCYEKFFA PECGRCQRKI LGEVINALKQ TWHVSCFVCV ACGKPIRNNV FHLEDGEPYC ETDYYALFGT ICRGCEFPIE AGDMFLEALG STWHDTCFVC SVCCESLEGQ TFFSKKDKPL CKKHAHSVNF
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
52,368 Da
Sequence Positions
2-591, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q62920
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Pdlim5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pdlim5 purchase

MBS1412368 is a recombinant protein targeting Pdlim5. Also known as Recombinant Rat PDZ and LIM domain protein 5 (Pdlim5). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Pdlim5. It may not necessarily be applicable to this product.

NCBI GI #
16758028
NCBI GeneID
64353
NCBI Accession #
NP_445778.1
UniProt Primary Accession #
Q62920
UniProt Related Accession #
Q62920
GenBank Nucleotide #
NM_053326.1
NCBI Official Full Name
PDZ and LIM domain protein 5
NCBI Official Synonym Full Names
PDZ and LIM domain 5
NCBI Official Symbol
Pdlim5
NCBI Official Synonym Symbols
Enh; Enh1
UniProt Protein Name
PDZ and LIM domain protein 5
UniProt Synonym Protein Names
Enigma homolog; Enigma-like PDZ and LIM domains protein
Protein Family
PDZ and LIM domain protein
UniProt Gene Name
Pdlim5
UniProt Synonym Gene Names
Enh
NCBI Protein Information
PDZ and LIM domain protein 5

NCBI Summary for Pdlim5

associates with protein kinase C; directs protein-protein interaction [RGD, Feb 2006]

UniProt Comments for Pdlim5

May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Isoforms lacking the LIM domains may negatively modulate the scaffolding activity of isoform 1. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons (PubMed:20097676). May be required to restrain postsynaptic growth of excitatory synapses. Isoform 1, but not isoform 2, expression favors spine thinning and elongation (PubMed:19900557).
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Research Articles on Pdlim5

1. results suggest that, in healthy conditions, RBM20 and RBM24 cooperate to promote the expression of short ENH isoforms.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Pdlim5 recombinant protein

 Reference Product  PubMed Publications
 Lmo7 recombinant protein  >1 publications with Pdlim5 and Lmo7

Diseases associated with Pdlim5 recombinant protein

 Disease Name  Pubmed Publications
 Depressive Disorder Antibodies  >4 publications with Pdlim5 and Depressive Disorder
 Neoplasms Antibodies  >4 publications with Pdlim5 and Neoplasms
 Carcinoma Antibodies  >2 publications with Pdlim5 and Carcinoma
 Cardiovascular Diseases Antibodies  >2 publications with Pdlim5 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >1 publications with Pdlim5 and Breast Neoplasms
 Fetal Death Antibodies  >1 publications with Pdlim5 and Fetal Death
 Carcinoma, Squamous Cell Antibodies  >1 publications with Pdlim5 and Carcinoma, Squamous Cell
 Heart Diseases Antibodies  >1 publications with Pdlim5 and Heart Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with Pdlim5 and Cell Transformation, Neoplastic
 Skin Diseases Antibodies  >1 publications with Pdlim5 and Skin Diseases

Organs/Tissues associated with Pdlim5 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with Pdlim5 and Brain
 Muscle Antibodies  >4 publications with Pdlim5 and Muscle
 Prostate Antibodies  >4 publications with Pdlim5 and Prostate
 Heart Antibodies  >3 publications with Pdlim5 and Heart
 Lung Antibodies  >1 publications with Pdlim5 and Lung
 Colon Antibodies  >1 publications with Pdlim5 and Colon
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