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MIG (bMIG) Bovine Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS141393

Introduction: Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belongs to the CXC chemokine family that is also known as Monokine induced by gamma INF (MIG). CXCL9 is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MIG (bMIG), Active Protein
Full Product Name
Recombinant Bovine MIG (CXCL9)
Product Gene Name
bMIG active protein
Product Synonym Names
Small inducible cytokine B9; CXCL9; Gamma INF-induced monokine; MIG; chemokine (C-X-C motif) ligand 9; CMK; Humig; SCYB9; crg-10; monokine induced by gamma-INF; MIG Bovine; MIG (CXCL9) Bovine Recombinant
Sequence
Amino acid: VPAIRNGRCS CINTSQGMIH PKSLKDLKQF APSPSCEKTE IIATMKNGNE ACLNPDLPEV KELIKEWEKQ VNQKKKQRKG KKYKKTKKVP KVKRSQRPSQ KKTT.
Host
E Coli
Form/Format
Sterile filtered white lyophilized (freeze-dried) powder.
Lyophilized from a 0.2um filtered concentrated solution in 20 mM PB and 500mM NaCl, pH 7.0.
Purity/Purification
>96.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Preparation and Storage
Lyophilized MIG although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C.
Upon reconstitution MIG (CXCL9) should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.
Please prevent freeze-thaw cycles.
3D Structure
ModBase 3D Structure for A9QWP9
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Solubility
It is recommended to reconstitute the lyophilized MIG (CXCL9) in sterile 18Momega-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
The biological activity determined by a chemotaxis bioassay using human lymphocytes is 0.1-1.0ng/ml.

Product Categories/Family for bMIG active protein

CHEMOKINES

Other Notes

Small volumes of bMIG active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for bMIG purchase

MBS141393 is an active protein targeting bMIG. Also known as Recombinant Bovine MIG (CXCL9). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for bMIG. It may not necessarily be applicable to this product.

NCBI GI #
172048423
NCBI GeneID
513990
NCBI Accession #
A9QWP9.1
UniProt Primary Accession #
A9QWP9
UniProt Related Accession #
A9QWP9
NCBI Official Full Name
C-X-C motif chemokine 9
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 9
NCBI Official Symbol
CXCL9
UniProt Protein Name
C-X-C motif chemokine 9
UniProt Synonym Protein Names
Small-inducible cytokine B9
Protein Family
Migration and invasion enhancer
UniProt Gene Name
CXCL9
UniProt Entry Name
CXCL9_BOVIN
NCBI Protein Information
C-X-C motif chemokine 9

UniProt Comments for bMIG

Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3 ().

Research Articles on bMIG

1. CXCK9 and CXCL10 chemokines displayed a trend of decreasing mRNA expression as lesion progressed, suggesting a higher level of importance during the early stages of the immune response to mycobacterial infection.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with bMIG active protein

 Reference Product  PubMed Publications
 CXCL10 active protein  >1091 publications with bMIG and CXCL10
 CXCR3 active protein  >545 publications with bMIG and CXCR3
 CXCL11 active protein  >436 publications with bMIG and CXCL11
 CCL5 active protein  >282 publications with bMIG and CCL5
 CCL20 active protein  >68 publications with bMIG and CCL20
 CCL19 active protein  >42 publications with bMIG and CCL19
 CXCR5 active protein  >8 publications with bMIG and CXCR5
 PPBP active protein  >1 publications with bMIG and PPBP
 GNB1 active protein  >1 publications with bMIG and GNB1

Pathways associated with bMIG active protein

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with bMIG active protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >483 publications with bMIG and Inflammation
 Necrosis Antibodies  >241 publications with bMIG and Necrosis
 Disease Models, Animal Antibodies  >182 publications with bMIG and Disease Models, Animal
 Nervous System Diseases Antibodies  >139 publications with bMIG and Nervous System Diseases
 Lung Diseases Antibodies  >138 publications with bMIG and Lung Diseases
 Liver Diseases Antibodies  >102 publications with bMIG and Liver Diseases
 Cardiovascular Diseases Antibodies  >72 publications with bMIG and Cardiovascular Diseases
 Fibrosis Antibodies  >70 publications with bMIG and Fibrosis
 Hypersensitivity Antibodies  >65 publications with bMIG and Hypersensitivity
 Neoplasms, Experimental Antibodies  >54 publications with bMIG and Neoplasms, Experimental

Organs/Tissues associated with bMIG active protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >85 publications with bMIG and Kidney
 Muscle Antibodies  >49 publications with bMIG and Muscle
 Intestine Antibodies  >43 publications with bMIG and Intestine
 Mammary Gland Antibodies  >4 publications with bMIG and Mammary Gland
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