Human TPD52L1 Recombinant Protein – Cat# MBS1414077

Tumor Protein D53 (TPD52L1) Human Recombinant Protein

Name: TPD52L1 Recombinant Protein; Tumor Protein D53; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1414077
Price: 500 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1414077

MBS1414077 is a recombinant protein targeting TPD52L1. Also known as Recombinant Human Tumor protein D53 (TPD52L1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$500 / 0.02 mg (Yeast) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Tumor protein D53 (TPD52L1), Recombinant Protein

Full Product Name

Recombinant Human Tumor protein D53 (TPD52L1)

Product Gene Name

TPD52L1 recombinant protein

Product Synonym Names

Tumor protein D53; hD53; Tumor protein D52-like 1

Sequence

MEAQAQGLLE TEPLQGTDED AVASADFSSM LSEEEKEELK AELVQLEDEI TTLRQVLSAK ERHLVEIKQK LGMNLMNELK QNFSKSWHDM QTTTAYKKTH ETLSHAGQKA TAAFSNVGTA ISKKFGDMSY SIRHSISMPA MRNSPTFKSF EERVETTVTS LKTKVGGTNP NGGSFEEVLS STAHASAQSL AGGSRRTKEE ELQC

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

49.4 kDa

Sequence Positions

1-144aa; Full Length

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

604069

3D Structure

ModBase 3D Structure for Q16890

Species

Homo sapiens (Human)

Product Categories/Family for TPD52L1 recombinant protein

Cell Biology

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TPD52L1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TPD52L1. It may not necessarily be applicable to this product.

NCBI GI #

51173744

NCBI GeneID

7164

NCBI Accession #

NP_001003395.1

UniProt Primary Accession #

Q16890

UniProt Secondary Accession #

O43397; Q5TC99; Q5TDQ0; Q9BUQ6; Q9C054; A8K757; A8K772; A8MUD2; A8MUJ7; A8MW70; F6V707

UniProt Related Accession #

Q16890

GenBank Nucleotide #

NM_001003395.1

NCBI Official Full Name

tumor protein D53 isoform 2

NCBI Official Synonym Full Names

tumor protein D52-like 1

NCBI Official Symbol

TPD52L1

NCBI Official Synonym Symbols

D53; hD53

UniProt Protein Name

Tumor protein D53

UniProt Synonym Protein Names

Tumor protein D52-like 1

Protein Family

Tumor protein

UniProt Gene Name

TPD52L1

UniProt Synonym Gene Names

hD53

UniProt Entry Name

TPD53_HUMAN

NCBI Protein Information

tumor protein D53

NCBI Summary for TPD52L1

This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined. [provided by RefSeq, Jul 2008]

UniProt Comments for TPD52L1

TPD52L1: a member of the tumor protein D52 (TPD52) family. Contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. Interacts with the apoptosis signal-regulating kinase 1 (ASK1) and positively regulates ASK1-induced apoptosis. Multiple alternatively spliced transcript variants have been observed.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 6q22-q23

Cellular Component: perinuclear region of cytoplasm; cytoplasm

Molecular Function: identical protein binding; protein binding; protein homodimerization activity; protein heterodimerization activity

Biological Process: positive regulation of MAP kinase activity; positive regulation of JNK cascade; regulation of caspase activity; G2/M transition of mitotic cell cycle

Research Articles on TPD52L1

1. The results indicate that tumor protein D52-like 1 genes are not ubiquitously expressed in leukemic bone marrow in children, and that RNA sample parameters may influence measures of gene expression more than commonly appreciated.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TPD52L1 recombinant protein

Reference Product	PubMed Publications
TPD52 recombinant protein	>7 publications with TPD52L1 and TPD52
TPD52L2 recombinant protein	>4 publications with TPD52L1 and TPD52L2
MAL2 recombinant protein	>2 publications with TPD52L1 and MAL2
YWHAB recombinant protein	>1 publications with TPD52L1 and YWHAB

Pathways associated with TPD52L1 recombinant protein

Products by Pathway	Pathway Diagram
Clathrin Derived Vesicle Budding Pathway antibodies	Clathrin Derived Vesicle Budding Pathway Diagram
Golgi Associated Vesicle Biogenesis Pathway antibodies	Golgi Associated Vesicle Biogenesis Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Trans-Golgi Network Vesicle Budding Pathway antibodies	Trans-Golgi Network Vesicle Budding Pathway Diagram

Diseases associated with TPD52L1 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>9 publications with TPD52L1 and Neoplasms
Breast Neoplasms Antibodies	>7 publications with TPD52L1 and Breast Neoplasms
Neoplasm Metastasis Antibodies	>1 publications with TPD52L1 and Neoplasm Metastasis
Ovarian Neoplasms Antibodies	>1 publications with TPD52L1 and Ovarian Neoplasms
Neoplasms, Experimental Antibodies	>1 publications with TPD52L1 and Neoplasms, Experimental
Inflammation Antibodies	>1 publications with TPD52L1 and Inflammation

Organs/Tissues associated with TPD52L1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>2 publications with TPD52L1 and Testis
Bone Antibodies	>1 publications with TPD52L1 and Bone
Skin Antibodies	>1 publications with TPD52L1 and Skin