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Pentraxin-2 (mPTX2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS141471

Introduction: PTX-2 or Pentraxin-2 is a phylogenetically conserved protein, commonly moving with homopentameric blood protein or with a protein that recognizes receptors of the innate immune system. The protein’s specific binding abilities may show that… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Pentraxin-2 (mPTX2), Recombinant Protein
Full Product Name
Recombinant Mouse Pentraxin-2
Product Gene Name
mPTX2 recombinant protein
Product Synonym Names
Serum amyloid P-component; SAP; Apcs; Sap; Ptx2; PTX2 Mouse; Pentraxin-2 Mouse Recombinant
Sequence
Amino acid: QTDLKRKVFV FPRESETDHV KLIPHLEKPL QNFTLCFRTY SDLSRSQSLF SYSVKGRDNE LLIYKEKVGE YSLYIGQSKV TVRGMEEYLS PVHLCTTWES SSGIVEFWVN GKPWVKKSLQ REYTVKAPPS IVLGQEQDNY GGGFQRSQSF VGEFSDLYMW DYVLTPQDIL FVYRDSPVNP NILNWQALNY EINGYVVIRP RVWDHHHHHH .
Host
HEK293
Form/Format
Sterile filtered clear solution.
PTX2 protein solution (0.25mg/ml) contains 10% glycerol in Phosphate Buffered Saline (pH 7.4).
Purity/Purification
>90.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks.
Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
3D Structure
ModBase 3D Structure for P12246

Product Categories/Family for mPTX2 recombinant protein

RECOMBINANT & NATURAL PROTEINS

Other Notes

Small volumes of mPTX2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for mPTX2 purchase

MBS141471 is a recombinant protein targeting mPTX2. Also known as Recombinant Mouse Pentraxin-2. Host: HEK293.

Additional Details

NCBI/Uniprot data below describe general gene information for mPTX2. It may not necessarily be applicable to this product.

NCBI GI #
134198
NCBI Accession #
P12246.2
UniProt Primary Accession #
P12246
NCBI Official Full Name
Serum amyloid P-component
UniProt Protein Name
Serum amyloid P-component
Protein Family
Neuronal pentraxin
UniProt Gene Name
Apcs
UniProt Synonym Gene Names
Ptx2; Sap; SAP
UniProt Entry Name
SAMP_MOUSE

UniProt Comments for mPTX2

APCS: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. Belongs to the pentaxin family.

Protein type: Secreted; Secreted, signal peptide; Chaperone

Cellular Component: extracellular matrix; extracellular space; protein complex; extracellular region; nucleus

Molecular Function: metal ion binding; complement component C1q binding; virion binding; calcium ion binding; carbohydrate binding

Biological Process: negative regulation of virion penetration into host cell; innate immune response; protein complex assembly; negative regulation of monocyte differentiation; negative regulation of viral reproduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with mPTX2 recombinant protein

 Reference Product  PubMed Publications
 Gsn recombinant protein  >2 publications with mPTX2 and Gsn
 App recombinant protein  >2 publications with mPTX2 and App
 Ttr recombinant protein  >2 publications with mPTX2 and Ttr
 Mfge8 recombinant protein  >1 publications with mPTX2 and Mfge8
 Fga recombinant protein  >1 publications with mPTX2 and Fga

Pathways associated with mPTX2 recombinant protein

 Products by Pathway  Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram

Diseases associated with mPTX2 recombinant protein

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1803 publications with mPTX2 and Cardiovascular Diseases
 Heart Diseases Antibodies  >1758 publications with mPTX2 and Heart Diseases
 Immune System Diseases Antibodies  >969 publications with mPTX2 and Immune System Diseases
 Inflammation Antibodies  >487 publications with mPTX2 and Inflammation
 Necrosis Antibodies  >272 publications with mPTX2 and Necrosis
 Brain Diseases Antibodies  >211 publications with mPTX2 and Brain Diseases
 Congenital Abnormalities Antibodies  >183 publications with mPTX2 and Congenital Abnormalities
 Heart Failure Antibodies  >154 publications with mPTX2 and Heart Failure
 Lung Diseases Antibodies  >141 publications with mPTX2 and Lung Diseases
 Hepatitis Antibodies  >89 publications with mPTX2 and Hepatitis

Organs/Tissues associated with mPTX2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >473 publications with mPTX2 and Bone Marrow
 Lymph Node Antibodies  >443 publications with mPTX2 and Lymph Node
 Mixed Antibodies  >209 publications with mPTX2 and Mixed
 Liver Antibodies  >166 publications with mPTX2 and Liver
 Muscle Antibodies  >116 publications with mPTX2 and Muscle
 Embryonic Tissue Antibodies  >35 publications with mPTX2 and Embryonic Tissue
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