Rat XCL1 Active Protein – Cat# MBS141481

Lymphotactin (XCL1) Rat Active Protein

Name: XCL1 Active Protein; Lymphotactin; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS141481
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS141481

Introduction: XCL1 is a small cytokine belongs to the XC chemokine family that is also known as lymphotactin. XCL1 is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary.… More details

$580 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lymphotactin (XCL1), Active Protein

Full Product Name

Recombinant Rat Lymphotactin (XCL1)

Product Gene Name

XCL1 active protein

Product Synonym Names

XCL1; Cytokine SCM-1; ATAC; Lymphotaxin; SCM-1-alpha; Small inducible cytokine C1; XC chemokine ligand 1; LTN; LPTN; SCM1; SCM-1; SCYC1; SCM-1a; Lymphotactin Rat; rLymphotactin; Lymphotactin (XCL1) Rat Recombinant

Sequence

Amino acid: VGTEVLQESI CVSLRTQRLP VQKIKTYTIK EGAMRAVIFV TKRGLRICAD PQAKWVKTAI KTVDGRASAS KSKAETIPTQ AQRSASTAVT LTG.

Host

E Coli

Form/Format

Sterile filtered white lyophilized (freeze-dried) powder.
Lyophilized from a 0.2um filtered concentrated solution in PBS, pH 7.4.

Purity/Purification

>97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Preparation and Storage

Lyophilized XCL1 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C.
Upon reconstitution Lymphotactin should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.
Please prevent freeze-thaw cycles.

3D Structure

ModBase 3D Structure for P51672

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Solubility

It is recommended to reconstitute the lyophilized Lymphotactin in sterile 18Momega-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Biological Activity

The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells < 100ng/ml, corresponding to a specific activity of > 1.0 × 104 IU/mg.

Product Categories/Family for XCL1 active protein

CHEMOKINES

Other Notes

Small volumes of XCL1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for XCL1 purchase

MBS141481 is an active protein targeting XCL1. Also known as Recombinant Rat Lymphotactin (XCL1). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for XCL1. It may not necessarily be applicable to this product.

NCBI GI #

19705461

NCBI GeneID

171371

NCBI Accession #

NP_599188.1

UniProt Primary Accession #

P51672

UniProt Related Accession #

P51672

GenBank Nucleotide #

NP_599188.1

NCBI Official Full Name

lymphotactin

NCBI Official Synonym Full Names

X-C motif chemokine ligand 1

NCBI Official Symbol

Xcl1

NCBI Official Synonym Symbols

Ltn; Scyc1

UniProt Protein Name

Lymphotactin

UniProt Synonym Protein Names

C motif chemokine 1; Cytokine SCM-1; Small-inducible cytokine C1

Protein Family

Lymphotactin

UniProt Gene Name

Xcl1

UniProt Synonym Gene Names

Ltn; Scyc1

NCBI Protein Information

lymphotactin

NCBI Summary for XCL1

mouse homolog is a cytokine with chemotactic activity for lymphocytes but not for monocytes or neutrophils [RGD, Feb 2006]

UniProt Comments for XCL1

Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.

Research Articles on XCL1

1. XCR1 is upregulated at sites of trigeminal nerve injury with a time course that correlates with the development of spontaneous activity at these sites. Exposure of trigeminal brainstem tissue to XCL1 induces expression of c-Fos, pERK and pp38 immunolabeling in trigeminal subnucleus caudalis, and induces increased spontaneous low-threshold activity indicative of hyperexcitability within nociceptive circuitry.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with XCL1 active protein

Reference Product	PubMed Publications
Xcr1 active protein	>38 publications with XCL1 and Xcr1
Ccl9 active protein	>3 publications with XCL1 and Ccl9
Ccl6 active protein	>1 publications with XCL1 and Ccl6

Pathways associated with XCL1 active protein

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Diseases associated with XCL1 active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>28 publications with XCL1 and Inflammation
Disease Models, Animal Antibodies	>19 publications with XCL1 and Disease Models, Animal
Necrosis Antibodies	>18 publications with XCL1 and Necrosis
Neoplasms, Experimental Antibodies	>16 publications with XCL1 and Neoplasms, Experimental
Lung Diseases Antibodies	>13 publications with XCL1 and Lung Diseases
Hypersensitivity Antibodies	>11 publications with XCL1 and Hypersensitivity
Cardiovascular Diseases Antibodies	>8 publications with XCL1 and Cardiovascular Diseases
Nervous System Diseases Antibodies	>7 publications with XCL1 and Nervous System Diseases
Ovarian Neoplasms Antibodies	>4 publications with XCL1 and Ovarian Neoplasms
Lung Neoplasms Antibodies	>3 publications with XCL1 and Lung Neoplasms

Organs/Tissues associated with XCL1 active protein

Organ/Tissue Name	Pubmed Publications
Ovary Antibodies	>1 publications with XCL1 and Ovary