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Pr Domain Zinc Finger Protein 5 (PRDM5) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1415633

This protein is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. More details

$1440 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PR domain zinc finger protein 5 (PRDM5), Recombinant Protein
Full Product Name
Recombinant Human PR domain zinc finger protein 5 (PRDM5)
Product Gene Name
PRDM5 recombinant protein
Product Synonym Gene Name
PRDM5
Sequence
MLGMYVPDRF SLKSSRVQDG MGLYTARRVR KGEKFGPFAG EKRMPEDLDE NMDYRLMWEV RGSKGEVLYI LDATNPRHSN WLRFVHEAPS QEQKNLAAIQ EGENIFYLAV EDIETDTELL IGYLDSDMEA EEEEQQIMTV IKEGEVENSR RQSTAGRKDR LGCKEDYACP QCESSFTSED ILAEHLQTLH QKPTEEKEFK CKNCGKKFPV KQALQRHVLQ CTAKSSLKES SRSFQCSVCN SSFSSASSFE QHQETCRGDA RFVCKADSCG KRLKSKDALK RHQENVHTGD PKKKLICSVC NKKCSSASSL QEHRKIHEIF DCQECMKKFI SANQLKRHMI THSEKRPYNC EICNKSFKRL DQVGAHKVIH SEDKPYKCKL CGKGFAHRNV YKNHKKTHSE ERPFQCEECK ALFRTPFSLQ RHLLIHNSER TFKCHHCDAT FKRKDTLNVH VQVVHERHKK YRCELCNKAF VTPSVLRSHK KTHTGEKEKI CPYCGQKFAS SGTLRVHIRS HTGERPYQCP YCEKGFSKND GLKMHIRTHT REKPYKCSEC SKAFSQKRGL DEHKRTHTGE KPFQCDVCDL AFSLKKMLIR HKMTHNPNRP LAECQFCHKK FTRNDYLKVH MDNIHGVADS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
58,124 Da
Sequence Positions
1-630, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
614161
3D Structure
ModBase 3D Structure for Q9NQX1
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PRDM5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRDM5 purchase

MBS1415633 is a recombinant protein targeting PRDM5. Also known as Recombinant Human PR domain zinc finger protein 5 (PRDM5). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for PRDM5. It may not necessarily be applicable to this product.

NCBI GI #
664806054
NCBI GeneID
11107
NCBI Accession #
NP_001287752.1
UniProt Primary Accession #
Q9NQX1
UniProt Secondary Accession #
Q0VAI9; Q0VAJ0; Q6NXQ7
UniProt Related Accession #
Q9NQX1
GenBank Nucleotide #
NM_001300823.1
NCBI Official Full Name
PR domain zinc finger protein 5 isoform 2
NCBI Official Synonym Full Names
PR/SET domain 5
NCBI Official Symbol
PRDM5
NCBI Official Synonym Symbols
BCS2; PFM2
UniProt Protein Name
PR domain zinc finger protein 5
UniProt Synonym Protein Names
PR domain-containing protein 5
Protein Family
PR domain zinc finger protein
UniProt Gene Name
PRDM5
UniProt Synonym Gene Names
PFM2
NCBI Protein Information
PR domain zinc finger protein 5

NCBI Summary for PRDM5

The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. [provided by RefSeq, Jul 2008]

UniProt Comments for PRDM5

Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells.
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Research Articles on PRDM5

1. Both Prdm 4 and Prdm 5 are expressed in human corneal endothelium, primary hCECs and in HCECs-12 cells, characterised by expression of the Na(+)/K(+)-ATPase.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PRDM5 recombinant protein

 Reference Product  PubMed Publications
 G9A recombinant protein  >1 publications with PRDM5 and G9A
 GFI1 recombinant protein  >1 publications with PRDM5 and GFI1
 HDAC1 recombinant protein  >1 publications with PRDM5 and HDAC1

Diseases associated with PRDM5 recombinant protein

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >6 publications with PRDM5 and Congenital Abnormalities
 Carcinoma, Hepatocellular Antibodies  >3 publications with PRDM5 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >2 publications with PRDM5 and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with PRDM5 and Liver Diseases
 Hepatitis Antibodies  >1 publications with PRDM5 and Hepatitis
 Breast Neoplasms Antibodies  >1 publications with PRDM5 and Breast Neoplasms
 Gonadal Disorders Antibodies  >1 publications with PRDM5 and Gonadal Disorders
 Hearing Loss Antibodies  >1 publications with PRDM5 and Hearing Loss
 Uterine Cervical Neoplasms Antibodies  >1 publications with PRDM5 and Uterine Cervical Neoplasms
 Eye Abnormalities Antibodies  >1 publications with PRDM5 and Eye Abnormalities

Organs/Tissues associated with PRDM5 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with PRDM5 and Lung
 Embryonic Tissue Antibodies  >2 publications with PRDM5 and Embryonic Tissue
 Liver Antibodies  >2 publications with PRDM5 and Liver
 Eye Antibodies  >1 publications with PRDM5 and Eye
 Vascular Antibodies  >1 publications with PRDM5 and Vascular
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