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Synapsin-2 (SYN2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1415692

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in… More details

$1375 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Synapsin-2 (SYN2), Recombinant Protein
Full Product Name
Recombinant Human Synapsin-2 (SYN2)
Product Gene Name
SYN2 recombinant protein
Product Synonym Gene Name
SYN2
Sequence
MMNFLRRRLS DSSFIANLPN GYMTDLQRPE PQQAPTPPPP GPGAASASAA PPTASPGPER TPPAASAPAP PPARTPSVGS SLFSSLSQAV KQTAASAGLV DAPGAAPAAA RKAKVLLVVD EPHADWAKCF RGKKVLGDYD IKVEQAEFSE LNLVAHADGT YAVDMQVLRN GTKVVRSFRP DFVLIRQHAF GMAENEDFRH LIIGMQYAGL PSINSLESIY NFCDKPWVFA QLVAIYKTLG GEKFPLIEQT YYPNHKEMLT LPTFPVVVKI GHAHSGMGKV KVENHYDFQD IASVVALTQT YATAEPFIDS KYDIRVQKIG NNYKAYMRTS ISGNWKTNTG SAMLEQIAMS DRYKLWVDTC SEMFGGLDIC AVKAVHGKDG KDYIFEVMDC SMPLIGEHQV EDRQLITELV ISKMNQLLSR TPALSPQRPL TTQQPQSGTL KDPDSSKTPP QRPPPQGGPG QPQGMQPPGK VLPPRRLPPG PSLPPSSSSS SSSSSSAPQR PGGPTTHGDA PSSSSSLAEA QPPLAAPPQK PQPHPQLNKS QSLTNAFSFS ESSFFRSSAN EDEAKAETIR SLRKSFASLF SD
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
52,162 Da
Sequence Positions
1-582, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
181500
3D Structure
ModBase 3D Structure for Q92777
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SYN2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SYN2 purchase

MBS1415692 is a recombinant protein targeting SYN2. Also known as Recombinant Human Synapsin-2 (SYN2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for SYN2. It may not necessarily be applicable to this product.

NCBI GI #
19924101
NCBI GeneID
6854
NCBI Accession #
NP_003169.2
UniProt Primary Accession #
Q92777
UniProt Secondary Accession #
A8MY98
UniProt Related Accession #
Q92777
GenBank Nucleotide #
NM_003178.5
NCBI Official Full Name
synapsin-2 isoform IIb
NCBI Official Synonym Full Names
synapsin II
NCBI Official Symbol
SYN2
NCBI Official Synonym Symbols
SYNII
UniProt Protein Name
Synapsin-2
UniProt Synonym Protein Names
Synapsin II
Protein Family
Sister chromatid cohesion 1 protein
UniProt Gene Name
SYN2
NCBI Protein Information
synapsin-2

NCBI Summary for SYN2

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite direction. [provided by RefSeq, Feb 2014]
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UniProt Comments for SYN2

Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons ().

Research Articles on SYN2

1. These findings contribute to previous work showing dysregulation of Synapsins, particularly SYN2, in mood disorders and improve our understanding of the regulatory mechanisms that precipitate these changes likely leading to the BD or MDD phenotype.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SYN2 recombinant protein

 Reference Product  PubMed Publications
 SYN1 recombinant protein  >10 publications with SYN2 and SYN1
 SYN3 recombinant protein  >6 publications with SYN2 and SYN3

Pathways associated with SYN2 recombinant protein

 Products by Pathway  Pathway Diagram
 Dopamine Neurotransmitter Release Cycle Pathway antibodies  Dopamine Neurotransmitter Release Cycle Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Neurotransmitter Release Cycle Pathway antibodies  Neurotransmitter Release Cycle Pathway Diagram
 Serotonin Neurotransmitter Release Cycle Pathway antibodies  Serotonin Neurotransmitter Release Cycle Pathway Diagram
 Transmission Across Chemical Synapses Pathway antibodies  Transmission Across Chemical Synapses Pathway Diagram

Diseases associated with SYN2 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >8 publications with SYN2 and Nervous System Diseases
 Schizophrenia Antibodies  >8 publications with SYN2 and Schizophrenia
 Epilepsy Antibodies  >7 publications with SYN2 and Epilepsy
 Disease Models, Animal Antibodies  >5 publications with SYN2 and Disease Models, Animal
 Seizures Antibodies  >3 publications with SYN2 and Seizures
 Memory Disorders Antibodies  >1 publications with SYN2 and Memory Disorders
 Cognition Disorders Antibodies  >1 publications with SYN2 and Cognition Disorders
 Prenatal Injuries Antibodies  >1 publications with SYN2 and Prenatal Injuries
 Nerve Degeneration Antibodies  >1 publications with SYN2 and Nerve Degeneration
 Inflammation Antibodies  >1 publications with SYN2 and Inflammation

Organs/Tissues associated with SYN2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with SYN2 and Brain
 Muscle Antibodies  >4 publications with SYN2 and Muscle
 Nerve Antibodies  >2 publications with SYN2 and Nerve
 Intestine Antibodies  >1 publications with SYN2 and Intestine
 Eye Antibodies  >1 publications with SYN2 and Eye
 Heart Antibodies  >1 publications with SYN2 and Heart
 Skin Antibodies  >1 publications with SYN2 and Skin
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