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C-Reactive Protein (mCRP) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS141615

C-Reactive Protein or CRP, is a protein, part of the pentraxin superfamily. Among the protein's activities, CRP can promote agglutination, swelling of the bacteria capsule, phagocytosis etc. this protein can also cause complement fixation via a… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C-Reactive Protein (mCRP), Recombinant Protein
Full Product Name
Recombinant Mouse C-Reactive Protein
Product Gene Name
mCRP recombinant protein
Product Synonym Names
mCRP; CRP Mouse; C-Reactive Protein Mouse Recombinant; C-reactive protein; pentraxin-related; Crp
Sequence
HEDMFKKAFV FPKESDTSYV SLEAESKKPL NTFTVCLHFY TALSTVRSFS VFSYATKKNS NDILIFWNKD KQYTFGVGGA EVRFMVSEIP EAPTHICASW ESATGIVEFW IDGKPKVRKS LHKGYTVGPD ASIILGQEQD SYGGDFDAKQ SLVGDIGDVN MWDFVLSPEQ ISTVYVGGTL SPNVLNWRAL NYKAQGDVFI KPQLWSLEHH HHHH
Host
Sf9, Baculovirus cells
Form/Format
Sterile filtered clear solution.
CRP solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH8.0), 1mM DTT, 0.1M PMSF and 40% glycerol.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks.
Store, frozen at -20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Molecular Weight
25,360 Da
3D Structure
ModBase 3D Structure for P14847

Product Categories/Family for mCRP recombinant protein

RECOMBINANT & NATURAL PROTEINS

Other Notes

Small volumes of mCRP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for mCRP purchase

MBS141615 is a recombinant protein targeting mCRP. Also known as Recombinant Mouse C-Reactive Protein. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for mCRP. It may not necessarily be applicable to this product.

NCBI GI #
408360035
NCBI GeneID
12944
NCBI Accession #
P14847.2
UniProt Primary Accession #
P14847
UniProt Secondary Accession #
E9PZ20
UniProt Related Accession #
P14847
NCBI Official Full Name
C-reactive protein
NCBI Official Synonym Full Names
C-reactive protein, pentraxin-related
NCBI Official Symbol
Crp
NCBI Official Synonym Symbols
AI255847
UniProt Protein Name
C-reactive protein
Protein Family
C-reactive protein
UniProt Gene Name
Crp
UniProt Synonym Gene Names
Ptx1
UniProt Entry Name
CRP_MOUSE
NCBI Protein Information
C-reactive protein; C-reactive protein, petaxin related

UniProt Comments for mCRP

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; growth cone; extracellular region; filopodium

Molecular Function: protein homodimerization activity; low-density lipoprotein receptor binding; metal ion binding; complement component C1q binding; low-density lipoprotein binding; cholesterol binding; calcium ion binding

Biological Process: protein polymerization; positive regulation of nitric oxide biosynthetic process; negative regulation of vasodilation; wound healing; positive regulation of superoxide release; acute-phase response; negative regulation of superoxide release; complement activation, classical pathway
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Research Articles on mCRP

1. The interactions of CRP and the BBB are a two-phase process, with increased paracellular permeability at a high dose that enables its entry into the CNS and serves to induce reactive gliosis and impair CNS function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with mCRP recombinant protein

 Reference Product  PubMed Publications
 Il6 recombinant protein  >454 publications with mCRP and Il6
 Serpine1 recombinant protein  >316 publications with mCRP and Serpine1
 Vegfa recombinant protein  >36 publications with mCRP and Vegfa
 Nos3 recombinant protein  >31 publications with mCRP and Nos3
 C4bp recombinant protein  >12 publications with mCRP and C4bp
 Lep recombinant protein  >9 publications with mCRP and Lep
 Selp recombinant protein  >8 publications with mCRP and Selp
 Vcam1 recombinant protein  >6 publications with mCRP and Vcam1
 Creb3l3 recombinant protein  >1 publications with mCRP and Creb3l3

Pathways associated with mCRP recombinant protein

 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram

Diseases associated with mCRP recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >11264 publications with mCRP and Inflammation
 Cardiovascular Diseases Antibodies  >8320 publications with mCRP and Cardiovascular Diseases
 Infection Antibodies  >4494 publications with mCRP and Infection
 Heart Diseases Antibodies  >3980 publications with mCRP and Heart Diseases
 Metabolic Diseases Antibodies  >3720 publications with mCRP and Metabolic Diseases
 Myocardial Ischemia Antibodies  >3197 publications with mCRP and Myocardial Ischemia
 Necrosis Antibodies  >3151 publications with mCRP and Necrosis
 Atherosclerosis Antibodies  >2829 publications with mCRP and Atherosclerosis
 Arthritis, Rheumatoid Antibodies  >1984 publications with mCRP and Arthritis, Rheumatoid
 Pain Antibodies  >1958 publications with mCRP and Pain

Organs/Tissues associated with mCRP recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1392 publications with mCRP and Liver
 Muscle Antibodies  >1142 publications with mCRP and Muscle
 Lung Antibodies  >1090 publications with mCRP and Lung
 Bone Marrow Antibodies  >286 publications with mCRP and Bone Marrow
 Uterus Antibodies  >59 publications with mCRP and Uterus
 Embryonic Tissue Antibodies  >57 publications with mCRP and Embryonic Tissue
 Thymus Antibodies  >32 publications with mCRP and Thymus
 Testis Antibodies  >8 publications with mCRP and Testis
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