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Intercellular Adhesion Molecule-5 (ICAM5) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS141627

Intercellular Adhesion Molecule-5 or ICAM-5 is a glycoprotein, part of the immunoglobulin family and located in the cell membrane. We can find ICAM-5 in telencephalic neurons, in a couple of adhesion activity, firstly heterophilic binding amid neurons and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Intercellular Adhesion Molecule-5 (ICAM5), Recombinant Protein
Full Product Name
Recombinant Human Intercellular Adhesion Molecule-5
Product Gene Name
ICAM5 recombinant protein
Product Synonym Names
ICAM5; ICAM5 Human; Intercellular Adhesion Molecule-5 Human Recombinant; Intercellular adhesion molecule 5; ICAM5; ICAM-5; Telencephalin; telencephalin; TLN; TLCN; TLNtelencephalin; TLCNTelencephalin
Sequence
LFGLSAVSQE PFWADLQPRV AFVERGGSLW LNCSTNCPRP ERGGLETSLR RNGTQRGLRW LARQLVDIRE PETQPVCFFR CARRTLQARG LIRTFQRPDR VELMPLPPWQ PVGENFTLSC RVPGAGPRAS LTLTLLRGAQ ELIRRSFAGE PPRARGAVLT ATVLARREDH GANFSCRAEL DLRPHGLGLF ENSSAPRELR TFSLSPDAPR LAAPRLLEVG SERPVSCTLD GLFPASEARV YLALGDQNLS PDVTLEGDAF VATATATASA EQEGARQLVC NVTLGGENRE TRENVTIYSF PAPLLTLSEP SVSEGQMVTV TCAAGAQALV TLEGVPAAVP GQPAQLQLNA TENDDRRSFF CDATLDVDGE TLIKNRSAEL RVLYAPRLDD SDCPRSWTWP EGPEQTLRCE ARGNPEPSVH CARSDGGAVL ALGLLGPVTR ALSGTYRCKA ANDQGEAVKD VTLTVEYAPA LDSVGCPERI TWLEGTEASL SCVAHGVPPP DVICVRSGEL GAVIEGLLRV AREHAGTYRC EATNPRGSAA KNVAVTVEYG PRFEEPSCPS NWTWVEGSGR LFSCEVDGKP QPSVKCVGSG GATEGVLLPL APPDPSPRAP RIPRVLAPGI YVCNATNRHG SVAKTVVVSA ESPPEMDEST CPSHQTWLEG AEASALACAA RGRPSPGVRC SREGIPWPEQ QRVSREDAGT YHCVATNAHG TDSRTVTVGV EYRPVVAELA ASPPGGVRPG GNFTLTCRAE AWPPAQISWR APPGALNIGL SSNNSTLSVA GAMGSHGGEY ECAATNAHGR HARRITVRVA GPWLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH
Host
HEK293 cells
Form/Format
Sterile filtered colorless solution
ICAM5 protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH7.4) and 10% glycerol.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks.
Store, frozen at -20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Molecular Weight
924
OMIM
601852
3D Structure
ModBase 3D Structure for Q9UMF0

Product Categories/Family for ICAM5 recombinant protein

RECOMBINANT & NATURAL PROTEINS

Other Notes

Small volumes of ICAM5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ICAM5 purchase

MBS141627 is a recombinant protein targeting ICAM5. Also known as Recombinant Human Intercellular Adhesion Molecule-5. Host: HEK293 cells.

Additional Details

NCBI/Uniprot data below describe general gene information for ICAM5. It may not necessarily be applicable to this product.

NCBI GI #
296439327
NCBI GeneID
7087
NCBI Accession #
Q9UMF0.3
UniProt Primary Accession #
Q9UMF0
UniProt Secondary Accession #
Q9Y6F3
UniProt Related Accession #
Q9UMF0
NCBI Official Full Name
Intercellular adhesion molecule 5
NCBI Official Synonym Full Names
intercellular adhesion molecule 5, telencephalin
NCBI Official Symbol
ICAM5
NCBI Official Synonym Symbols
TLN; TLCN
UniProt Protein Name
Intercellular adhesion molecule 5
UniProt Synonym Protein Names
Telencephalin
Protein Family
Intercellular adhesion molecule
UniProt Gene Name
ICAM5
UniProt Synonym Gene Names
TLCN; TLN; ICAM-5
UniProt Entry Name
ICAM5_HUMAN
NCBI Protein Information
intercellular adhesion molecule 5; ICAM-5; telencephalin

NCBI Summary for ICAM5

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008]
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UniProt Comments for ICAM5

ICAM5: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). Belongs to the immunoglobulin superfamily. ICAM family.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: integrin binding; protein binding

Biological Process: cell-cell adhesion; cell adhesion; phagocytosis
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Research Articles on ICAM5

1. ICAM5 V301I and rs281439 variants may contribute to the susceptibility of breast cancer. [Meta-analysis]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ICAM5 recombinant protein

 Reference Product  PubMed Publications
 ITGB2 recombinant protein  >4 publications with ICAM5 and ITGB2
 PSEN1 recombinant protein  >2 publications with ICAM5 and PSEN1
 ITGAL recombinant protein  >2 publications with ICAM5 and ITGAL

Diseases associated with ICAM5 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >9 publications with ICAM5 and Nervous System Diseases
 Brain Diseases Antibodies  >7 publications with ICAM5 and Brain Diseases
 Skin Diseases Antibodies  >7 publications with ICAM5 and Skin Diseases
 Breast Neoplasms Antibodies  >6 publications with ICAM5 and Breast Neoplasms
 Epilepsy Antibodies  >5 publications with ICAM5 and Epilepsy
 Seizures Antibodies  >3 publications with ICAM5 and Seizures
 Inflammation Antibodies  >2 publications with ICAM5 and Inflammation
 Skin Neoplasms Antibodies  >2 publications with ICAM5 and Skin Neoplasms
 Colorectal Neoplasms Antibodies  >2 publications with ICAM5 and Colorectal Neoplasms
 Cardiovascular Diseases Antibodies  >1 publications with ICAM5 and Cardiovascular Diseases

Organs/Tissues associated with ICAM5 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >43 publications with ICAM5 and Brain
 Embryonic Tissue Antibodies  >3 publications with ICAM5 and Embryonic Tissue
 Thyroid Antibodies  >1 publications with ICAM5 and Thyroid
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