Cercopithecine Herpesvirus 1 US12 Recombinant Protein – Cat# MBS1416765

ICP47 Protein (US12) Cercopithecine Herpesvirus 1 Recombinant Protein

Name: US12 Recombinant Protein; Cercopithecine Herpesvirus 1; MyBioSource
Brand: MyBioSource
SKU: MBS1416765
Price: 700 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1416765

MBS1416765 is a recombinant protein targeting US12. Also known as Recombinant Cercopithecine herpesvirus 1 ICP47 protein (US12). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$700 / 0.05 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ICP47 protein (US12), Recombinant Protein

Full Product Name

Recombinant Cercopithecine herpesvirus 1 ICP47 protein (US12)

Product Gene Name

US12 recombinant protein

Product Synonym Names

ICP47 protein; Immediate-early protein IE12; Immediate-early-5; Infected cell protein 47; US12 protein; Vmw12

Sequence

MSSRYLAAVD DYLHHPSPRY QAHVDLRREL RAYADEERRE AARAIAHPER PLLPPPATQA APPQPSTREA AHPSAPTAAS S

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

8,946 Da

Sequence Positions

1-81aa; full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q8JP02

Species

Cercopithecine herpesvirus 1 (strain E2490) (CeHV-1) (Simian herpes B virus)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of US12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for US12. It may not necessarily be applicable to this product.

NCBI GI #

30984500

NCBI GeneID

1487466

NCBI Accession #

NP_851932.1

UniProt Primary Accession #

Q8JP02

UniProt Secondary Accession #

Q8V717

GenBank Nucleotide #

NC_004812.1

NCBI Official Full Name

TAP transporter inhibitor ICP47

NCBI Official Symbol

US12

UniProt Protein Name

ICP47 protein

UniProt Synonym Protein Names

Immediate-early protein IE12; Immediate-early-5; Infected cell protein 47; US12 protein; Vmw12

Protein Family

ICP47 protein

UniProt Gene Name

US12

UniProt Entry Name

ICP47_CHV1E

NCBI Protein Information

inhibits antigen presentation; TAP transporter inhibitor ICP47

UniProt Comments for US12

Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.